0638/10 | Tocris Bioscience 0638/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

0638/10

catalog :

0638/10

quantity :

10 mg (also 50 mg)

price :

112 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Gadgaard C, Jensen A. Functional characterization of 5-HT1A and 5-HT1B serotonin receptor signaling through G-protein-activated inwardly rectifying K+ channels in a fluorescence-based membrane potential assay. Biochem Pharmacol. 2020;175:113870 pubmed publisher
Khatri N, Simpson K, Lin R, Paul I. Lasting neurobehavioral abnormalities in rats after neonatal activation of serotonin 1A and 1B receptors: possible mechanisms for serotonin dysfunction in autistic spectrum disorders. Psychopharmacology (Berl). 2014;231:1191-200 pubmed publisher
Tung S, Hardy A, Wheeler M, Belsham D. Serotonin (5-HT) activation of immortalized hypothalamic neuronal cells through the 5-HT1B serotonin receptor. Endocrinology. 2012;153:4862-73 pubmed
Maciag D, Coppinger D, Paul I. Evidence that the deficit in sexual behavior in adult rats neonatally exposed to citalopram is a consequence of 5-HT1 receptor stimulation during development. Brain Res. 2006;1125:171-5 pubmed

product information

master code :

638

SKU :

0638/10

product name :

CGS 12066B dimaleate

unit size :

10 mg (also 50 mg)

description :

5-HT1B agonist

target :

5-HT1B Receptor Agonists

category :

Small Molecules

purity :

98%

observed molecular weight :

566.49

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

CGS 12066B dimaleate is a 5-HT1B full agonist, 10-fold selective over 5-HT1A and 1000-fold selective over 5-HT2C receptors. Centrally active following systemic administration.

top caption :

5-HT1B agonist

extended description :

5-HT1B agonist

chemical name text :

7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo[1,2-a]-quinoxaline dimaleate

formula :

C17H17F3N4.2C4H4O4

formula text :

C17H17F3N4.2C4H4O4

cas num :

109028-10-6

USD :

112 USD

product details :

5-HT1B agonist

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage