product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
0624/100
catalog :
0624/100
quantity :
100 mg
price :
109 USD
more info or order :
citations: 15
Reference
Sofia Beas B, Gu X, Leng Y, Koita O, Rodriguez Gonzalez S, Kindel M, et al. A ventrolateral medulla-midline thalamic circuit for hypoglycemic feeding. Nat Commun. 2020;11:6218 pubmed publisher
Kilpatrick L, Alcobia D, White C, Peach C, Glenn J, Zimmerman K, et al. Complex Formation between VEGFR2 and the β2-Adrenoceptor. Cell Chem Biol. 2019;26:830-841.e9 pubmed publisher
Gungor N, Yamamoto R, PARE D. Glutamatergic and gabaergic ventral BNST neurons differ in their physiological properties and responsiveness to noradrenaline. Neuropsychopharmacology. 2018;43:2126-2133 pubmed publisher
McKeithan W, Savchenko A, YU M, Cerignoli F, Bruyneel A, Price J, et al. An Automated Platform for Assessment of Congenital and Drug-Induced Arrhythmia with hiPSC-Derived Cardiomyocytes. Front Physiol. 2017;8:766 pubmed publisher
Patsouris D, Qi P, Abdullahi A, Stanojcic M, Chen P, Parousis A, et al. Burn Induces Browning of the Subcutaneous White Adipose Tissue in Mice and Humans. Cell Rep. 2015;13:1538-44 pubmed publisher
Stoddart L, Johnstone E, Wheal A, Goulding J, Robers M, Machleidt T, et al. Application of BRET to monitor ligand binding to GPCRs. Nat Methods. 2015;12:661-663 pubmed publisher
Gherbi K, May L, Baker J, Briddon S, Hill S. Negative cooperativity across β1-adrenoceptor homodimers provides insights into the nature of the secondary low-affinity CGP 12177 β1-adrenoceptor binding conformation. FASEB J. 2015;29:2859-71 pubmed publisher
Skelly M, Weiner J. Chronic treatment with prazosin or duloxetine lessens concurrent anxiety-like behavior and alcohol intake: evidence of disrupted noradrenergic signaling in anxiety-related alcohol use. Brain Behav. 2014;4:468-83 pubmed publisher
Gherbi K, Briddon S, Hill S. Detection of the secondary, low-affinity ?1 -adrenoceptor site in living cells using the fluorescent CGP 12177 derivative BODIPY-TMR-CGP. Br J Pharmacol. 2014;171:5431-45 pubmed publisher
Bucher E, Fox M, Kim L, Kirkpatrick D, Rodeberg N, Belle A, et al. Medullary norepinephrine neurons modulate local oxygen concentrations in the bed nucleus of the stria terminalis. J Cereb Blood Flow Metab. 2014;34:1128-37 pubmed publisher
Hansen N, Manahan Vaughan D. Locus Coeruleus Stimulation Facilitates Long-Term Depression in the Dentate Gyrus That Requires Activation of ?-Adrenergic Receptors. Cereb Cortex. 2015;25:1889-96 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Rankovic V, Landgraf P, Kanyshkova T, Ehling P, Meuth S, Kreutz M, et al. Modulation of calcium-dependent inactivation of L-type Ca2+ channels via ?-adrenergic signaling in thalamocortical relay neurons. PLoS ONE. 2011;6:e27474 pubmed publisher
Meitzen J, Luoma J, Stern C, Mermelstein P. ?1-Adrenergic receptors activate two distinct signaling pathways in striatal neurons. J Neurochem. 2011;116:984-95 pubmed publisher
Shi M, Liu D, Duan H, Han C, Wei B, Qian L, et al. Catecholamine up-regulates MMP-7 expression by activating AP-1 and STAT3 in gastric cancer. Mol Cancer. 2010;9:269 pubmed publisher
product information
master code :
624
SKU :
0624/100
product name :
Propranolol hydrochloride
unit size :
100 mg
description :
antagonist
target :
Non-selective Adrenergic beta Receptor Antagonists
category :
Small Molecules
observed molecular weight :
295.81
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Propranolol hydrochloride is an -adrenergic antagonist. . R-enantiomer, S-enantiomer and Glycol Metabolite also available.
extended description :
antagonist
chemical name text :
(RS)-1-[(1-Methylethyl)amino]-3-(1-naphthalenyloxy)-2-propanol hydrochloride
formula :
C16H21NO2.HCl
formula text :
C16H21NO2.HCl
cas num :
318-98-9
USD :
109 USD
product details :
antagonist
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK