AG 555 | Tocris Bioscience 0618 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

AG 555

catalog :

0618

quantity :

10 mg (also 50 mg)

price :

110 USD

more info or order :

Tocris Bioscience product webpage

product information

brand :

Tocris

master code :

0618

SKU :

0618/10

product name :

AG 555

description :

Potent EGFR-kinase inhibitor

target :

EGF Receptor Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

322.36

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Potent epidermal growth factor receptor (EGFR) kinase inhibitor (IC50 = 0.7 u M) that displays 50-fold and 140-fold selectivity over ErbB2 and insulin receptor kinase respectively. Induce G1 growth arrest selectively in transformed cells (IC50 values are 6.4 and 9.4 M in HPV16-immortalized and normal keratinocytes respectively).

catalog number base :

618

product keywords :

Potent EGFR kinase inhibitors inhibits Epidermal Growth Factors Receptors ErbB Her Tyrosine Kinases RTKs AG555 Tyrphostin AG 555 Tyrphostin AG 555 EGFR 0618,

extended description :

Potent EGFR-kinase inhibitor

chemical name text :

(E)-2-Cyano-3-(3,4-dihydroxyphenyl)-N-(3-phenylpropyl)-2-propenamide

formula :

C 19 H 18 N 2 O 3

formula text :

C19H18N2O3

cas num :

133550-34-2

2020 USD :

122

2021 USD :

110 USD

alt names :

Tyrphostin AG 555

storage :

Desiccate at +4°C

more info or order :

Tocris Bioscience product webpage