product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Nimodipine
catalog :
0600
quantity :
100 mg
price :
119 USD
more info or order :
citations: 30
Reference
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Doshina A, Gourgue F, Onizuka M, Opsomer R, Wang P, Ando K, et al. Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission. Sci Rep. 2017;7:370 pubmed publisher
Bellono N, Leitch D, Julius D. Molecular basis of ancestral vertebrate electroreception. Nature. 2017;543:391-396 pubmed publisher
Robinson S, Lee T, Christie D, Birch N. Tissue plasminogen activator inhibits NMDA-receptor-mediated increases in calcium levels in cultured hippocampal neurons. Front Cell Neurosci. 2015;9:404 pubmed publisher
Ciani L, Marzo A, Boyle K, Stamatakou E, Lopes D, Anane D, et al. Wnt signalling tunes neurotransmitter release by directly targeting Synaptotagmin-1. Nat Commun. 2015;6:8302 pubmed publisher
Dilger E, Krahe T, Morhardt D, Seabrook T, Shin H, Guido W. Absence of plateau potentials in dLGN cells leads to a breakdown in retinogeniculate refinement. J Neurosci. 2015;35:3652-62 pubmed publisher
Pourbadie H, Naderi N, Mehranfard N, Janahmadi M, Khodagholi F, Motamedi F. Preventing effect of L-type calcium channel blockade on electrophysiological alterations in dentate gyrus granule cells induced by entorhinal amyloid pathology. PLoS ONE. 2015;10:e0117555 pubmed publisher
Gan K, Silverman M. Dendritic and axonal mechanisms of Ca2+ elevation impair BDNF transport in Aβ oligomer-treated hippocampal neurons. Mol Biol Cell. 2015;26:1058-71 pubmed publisher
Schöbel N, Radtke D, Kyereme J, Wollmann N, Cichy A, Obst K, et al. Astringency is a trigeminal sensation that involves the activation of G protein-coupled signaling by phenolic compounds. Chem Senses. 2014;39:471-87 pubmed publisher
Clemens A, Johnston D. Age- and location-dependent differences in store depletion-induced h-channel plasticity in hippocampal pyramidal neurons. J Neurophysiol. 2014;111:1369-82 pubmed publisher
Diekman C, Belle M, Irwin R, Allen C, Piggins H, Forger D. Causes and consequences of hyperexcitation in central clock neurons. PLoS Comput Biol. 2013;9:e1003196 pubmed publisher
Elmer B, Estes M, Barrow S, McAllister A. MHCI requires MEF2 transcription factors to negatively regulate synapse density during development and in disease. J Neurosci. 2013;33:13791-804 pubmed publisher
Siddoway B, Altimimi H, Hou H, Petralia R, Xu B, Stellwagen D, et al. An essential role for inhibitor-2 regulation of protein phosphatase-1 in synaptic scaling. J Neurosci. 2013;33:11206-11 pubmed publisher
Liu M, Kang S, Shi T, Koga K, Zhang M, Collingridge G, et al. Long-term potentiation of synaptic transmission in the adult mouse insular cortex: multielectrode array recordings. J Neurophysiol. 2013;110:505-21 pubmed publisher
Schöbel N, Radtke D, Lübbert M, Gisselmann G, Lehmann R, Cichy A, et al. Trigeminal ganglion neurons of mice show intracellular chloride accumulation and chloride-dependent amplification of capsaicin-induced responses. PLoS ONE. 2012;7:e48005 pubmed publisher
Colgan L, Cavolo S, Commons K, Levitan E. Action potential-independent and pharmacologically unique vesicular serotonin release from dendrites. J Neurosci. 2012;32:15737-46 pubmed publisher
Jurgens C, Bell K, McQuiston A, Guido W. Optogenetic stimulation of the corticothalamic pathway affects relay cells and GABAergic neurons differently in the mouse visual thalamus. PLoS ONE. 2012;7:e45717 pubmed publisher
Hulme S, Jones O, Ireland D, Abraham W. Calcium-dependent but action potential-independent BCM-like metaplasticity in the hippocampus. J Neurosci. 2012;32:6785-94 pubmed publisher
Saliba R, Kretschmannova K, Moss S. Activity-dependent phosphorylation of GABAA receptors regulates receptor insertion and tonic current. EMBO J. 2012;31:2937-51 pubmed publisher
Shulga A, Magalhães A, Autio H, Plantman S, Di Lieto A, Nykjær A, et al. The loop diuretic bumetanide blocks posttraumatic p75NTR upregulation and rescues injured neurons. J Neurosci. 2012;32:1757-70 pubmed publisher
Dilger E, Shin H, Guido W. Requirements for synaptically evoked plateau potentials in relay cells of the dorsal lateral geniculate nucleus of the mouse. J Physiol. 2011;589:919-37 pubmed publisher
Higley M, Sabatini B. Competitive regulation of synaptic Ca2+ influx by D2 dopamine and A2A adenosine receptors. Nat Neurosci. 2010;13:958-66 pubmed publisher
Murray K, Nakae A, Stephens M, Rank M, D Amico J, Harvey P, et al. Recovery of motoneuron and locomotor function after spinal cord injury depends on constitutive activity in 5-HT2C receptors. Nat Med. 2010;16:694-700 pubmed publisher
Grey K, Burrell B. Co-induction of LTP and LTD and its regulation by protein kinases and phosphatases. J Neurophysiol. 2010;103:2737-46 pubmed publisher
Wu W, Chan C, Surmeier D, Disterhoft J. Coupling of L-type Ca2+ channels to KV7/KCNQ channels creates a novel, activity-dependent, homeostatic intrinsic plasticity. J Neurophysiol. 2008;100:1897-908 pubmed publisher
Haeberle H, Bryan L, Vadakkan T, Dickinson M, Lumpkin E. Swelling-activated Ca2+ channels trigger Ca2+ signals in Merkel cells. PLoS ONE. 2008;3:e1750 pubmed publisher
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product information
brand :
Tocris
master code :
0600
SKU :
0600/100
product name :
Nimodipine
description :
CaV1.x blocker
target :
Voltage-gated Calcium Channel Blockers
category :
Small Molecules
unit size :
100 mg
purity :
99%
observed molecular weight :
418.45
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
L-type Ca2+ channel blocker. Induces autophagy.
catalog number base :
600
product keywords :
Ca2+ channel blockers L-type Calcium CaV Channels voltage-gated voltage-dependent Cav1.x Channels Autophagy 0600, Voltage-gated calcium channel blocker, voltage gated calcium channel, high-voltage activated Ca2+ channel, high voltage gated ca2+ channel
extended description :
CaV1.x blocker
chemical name text :
1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-methyloxyethyl 1-methylethyl ester
formula :
C 21 H 26 N 2 O 7
formula text :
C21H26N2O7
cas num :
66085-59-4
2020 USD :
114
2021 USD :
119 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK