product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
SNAP
catalog :
0598
quantity :
10 mg (also 50 mg)
price :
76 USD
more info or order :
citations: 9
Reference
Polter A, Barcomb K, Chen R, Dingess P, Graziane N, Brown T, et al. Constitutive activation of kappa opioid receptors at ventral tegmental area inhibitory synapses following acute stress. elife. 2017;6: pubmed publisher
Sanchez A, Martinez P, Munoz M, Benedito S, Garcia Sacristan A, Hernandez M, et al. Endothelin-1 contributes to endothelial dysfunction and enhanced vasoconstriction through augmented superoxide production in penile arteries from insulin-resistant obese rats: role of ET(A) and ET(B) receptors. Br J Pharmacol. 2014;171:5682-95 pubmed publisher
Rodríguez Muñoz M, de la Torre Madrid E, Sánchez Blázquez P, Garzón J. NO-released zinc supports the simultaneous binding of Raf-1 and PKC? cysteine-rich domains to HINT1 protein at the mu-opioid receptor. Antioxid Redox Signal. 2011;14:2413-25 pubmed publisher
Cheng Q, Sedlic F, Pravdic D, Bosnjak Z, Kwok W. Biphasic effect of nitric oxide on the cardiac voltage-dependent anion channel. FEBS Lett. 2011;585:328-34 pubmed publisher
Sunters A, Armstrong V, Zaman G, Kypta R, Kawano Y, Lanyon L, et al. Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5 r. J Biol Chem. 2010;285:8743-58 pubmed publisher
Huang C, Hsu K. Activation of muscarinic acetylcholine receptors induces a nitric oxide-dependent long-term depression in rat medial prefrontal cortex. Cereb Cortex. 2010;20:982-96 pubmed publisher
Yang S, Cox C. Modulation of inhibitory activity by nitric oxide in the thalamus. J Neurophysiol. 2007;97:3386-95 pubmed
Sachs D, Cunha F, Ferreira S. Peripheral analgesic blockade of hypernociception: activation of arginine/NO/cGMP/protein kinase G/ATP-sensitive K+ channel pathway. Proc Natl Acad Sci U S A. 2004;101:3680-5 pubmed
Nistri S, Mazzetti L, Failli P, Bani D. High-Yield Method for Isolation and Culture of Endothelial Cells from Rat Coronary Blood Vessels Suitable for Analysis of Intracellular Calcium and Nitric Oxide Biosynthetic Pathways. Biol Proced Online. 2002;4:32-37 pubmed
product information
brand :
Tocris
master code :
0598
SKU :
0598/10
product name :
SNAP
description :
A stable analog of endogenous S-nitroso compounds
target :
Nitric Oxide Donor/Precursor Compounds
category :
Small Molecules
unit size :
10 mg (also 50 mg)
observed molecular weight :
220.24
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
A stable analog of endogenous S-nitroso compounds. A source of NO in vivo which unlike organic O-nitrates does not induce tolerance. Decomposes slowly in solution with a t of 37h.
catalog number base :
598
product keywords :
stable endogenous S-nitroso ROS Donors NO Precursors Nitric Oxide Signaling Signalling NO Donors/ Precursors ROS Donors 0598,
extended description :
A stable analog of endogenous S-nitroso compounds
chemical name text :
(S)-Nitroso-N-acetylpenicillamine
formula :
C 7 H 12 N 2 O 4 S
formula text :
C7H12N2O4S
cas num :
79032-48-7
2020 USD :
72
2021 USD :
76 USD
storage :
Store at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK