product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
NPPB
catalog :
0593
quantity :
50 mg
price :
195 USD
more info or order :
citations: 9
Reference
Morethson P. Extracellular fluid flow and chloride content modulate H(+) transport by osteoclasts. BMC Cell Biol. 2015;16:20 pubmed publisher
Harper M, Poole A. Chloride channels are necessary for full platelet phosphatidylserine exposure and procoagulant activity. Cell Death Dis. 2013;4:e969 pubmed publisher
Grant J, Tran V, Bhattacharya S, Bianchi L. Ionic currents of human trabecular meshwork cells from control and glaucoma subjects. J Membr Biol. 2013;246:167-75 pubmed publisher
Sun X, Wang X, Wang G, Xia Y, Liu S, Qu M, et al. Lubiprostone reverses the inhibitory action of morphine on mucosal secretion in human small intestine. Dig Dis Sci. 2011;56:330-8 pubmed publisher
Sagheddu C, Boccaccio A, Dibattista M, Montani G, Tirindelli R, Menini A. Calcium concentration jumps reveal dynamic ion selectivity of calcium-activated chloride currents in mouse olfactory sensory neurons and TMEM16b-transfected HEK 293T cells. J Physiol. 2010;588:4189-204 pubmed publisher
Fei G, Wang Y, Liu S, Hu H, Wang G, Qu M, et al. Stimulation of mucosal secretion by lubiprostone (SPI-0211) in guinea pig small intestine and colon. Am J Physiol Gastrointest Liver Physiol. 2009;296:G823-32 pubmed publisher
Silverman W, Locovei S, Dahl G. Probenecid, a gout remedy, inhibits pannexin 1 channels. Am J Physiol Cell Physiol. 2008;295:C761-7 pubmed publisher
Fioretti B, Pietrangelo T, Catacuzzeno L, Franciolini F. Intermediate-conductance Ca2+-activated K+ channel is expressed in C2C12 myoblasts and is downregulated during myogenesis. Am J Physiol Cell Physiol. 2005;289:C89-96 pubmed
Li Q, Dong C, Deng A, Katsumata M, Nakadai A, Kawada T, et al. Hemolysis of erythrocytes by granulysin-derived peptides but not by granulysin. Antimicrob Agents Chemother. 2005;49:388-97 pubmed
product information
brand :
Tocris
master code :
0593
SKU :
0593/50
product name :
NPPB
description :
Inhibits calcium-sensitive chloride currents
target :
Calcium-activated Chloride Channel Blockers
category :
Small Molecules
unit size :
50 mg
purity :
99%
observed molecular weight :
300.31
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Inhibits calcium-sensitive chloride currents (10 M). Putative GPR35 agonist.
catalog number base :
593
product keywords :
Chloride channel blockers Cl- Channels GPR35 Ca2+-Activated Chloride Channels 0593,
extended description :
Inhibits calcium-sensitive chloride currents
chemical name text :
5-Nitro-2-(3-phenylpropylamino)benzoic acid
formula :
C 16 H 16 N 2 O 4
formula text :
C16H16N2O4
cas num :
107254-86-4
2020 USD :
187
2021 USD :
195 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK