Metergoline | Tocris Bioscience 0590 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Metergoline

catalog :

0590

quantity :

10 mg (also 50 mg)

price :

75 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Wang Y, Mao X, Li T, Gong N, Zhang M. Dezocine exhibits antihypersensitivity activities in neuropathy through spinal μ-opioid receptor activation and norepinephrine reuptake inhibition. Sci Rep. 2017;7:43137 pubmed publisher
Chan J, McCorvy J, Acharya S, Johns M, Day T, Roth B, et al. A Miniaturized Screen of a Schistosoma mansoni Serotonergic G Protein-Coupled Receptor Identifies Novel Classes of Parasite-Selective Inhibitors. PLoS Pathog. 2016;12:e1005651 pubmed publisher
Lee J, Liu J, Shin M, Hong M, Nah S, Bae H. Metergoline inhibits the neuronal Nav1.2 voltage-dependent Na(+) channels expressed in Xenopus oocytes. Acta Pharmacol Sin. 2014;35:862-8 pubmed publisher
Woo R, Li X, Tao Y, Carpenter Hyland E, Huang Y, Weber J, et al. Neuregulin-1 enhances depolarization-induced GABA release. Neuron. 2007;54:599-610 pubmed

product information

brand :

Tocris

master code :

0590

SKU :

0590/10

product name :

Metergoline

description :

5-HT2 antagonist. Also 5-HT1 antagonist and 5-HT1D ligand. Has moderate affinity for 5-HT6 and high affinity for 5-HT7

target :

Non-selective 5-HT2 Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

observed molecular weight :

403.52

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Antagonist at 5-HT1/5-HT2 with activity at 5-HT1D. Has moderate affinity for 5-HT6 and high affinity for 5-HT7.

catalog number base :

590

product keywords :

moderate affinity 5-HT6 high 5-HT7 5-HT1 5-HT2 antagonists 5-HT1D ligand Serotonin Receptors 5-Hydroxytryptamine 5-HT Non-Selective Non-selective 5-HT2 5-HT7 Receptors 5-HT6 Receptors 0590,

extended description :

5-HT2 antagonist. Also 5-HT1 antagonist and 5-HT1D ligand. Has moderate affinity for 5-HT6 and high affinity for 5-HT7

chemical name text :

[(8 )-1,6-Dimethylergolin-8-yl)methyl]carbamic acid phenylmethyl ester

formula :

C 25 H 29 N 3 O 2

formula text :

C25H29N3O2

cas num :

17692-51-2

2020 USD :

2021 USD :

75 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage