product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
L-NIO dihydrochloride
catalog :
0546
quantity :
10 mg (also 50 mg)
price :
86 USD
more info or order :
citations: 8
Reference
Lu Q, Feng X, Tong N, Sun H, Ding L, Wang Y, et al. Neuronal and Endothelial Nitric Oxide Synthases in the Paraventricular Nucleus Modulate Sympathetic Overdrive in Insulin-Resistant Rats. PLoS ONE. 2015;10:e0140762 pubmed publisher
Bergeron L, Willcox J, Alibhai F, Connell B, Saleh T, Wilson B, et al. Relaxin peptide hormones are protective during the early stages of ischemic stroke in male rats. Endocrinology. 2015;156:638-46 pubmed publisher
Penumarti A, Abdel Rahman A. Neuronal nitric oxide synthase-dependent elevation in adiponectin in the rostral ventrolateral medulla underlies g protein-coupled receptor 18-mediated hypotension in conscious rats. J Pharmacol Exp Ther. 2014;351:44-53 pubmed publisher
Gross G, Hsu A, Pfeiffer A, Nithipatikom K. Roles of endothelial nitric oxide synthase (eNOS) and mitochondrial permeability transition pore (MPTP) in epoxyeicosatrienoic acid (EET)-induced cardioprotection against infarction in intact rat hearts. J Mol Cell Cardiol. 2013;59:20-9 pubmed publisher
Wu Y, Wang L, Lin C, Lin Y, Zhou M, Chen L, et al. Vasorelaxin: a novel arterial smooth muscle-relaxing eicosapeptide from the skin secretion of the Chinese piebald odorous frog (Odorrana schmackeri). PLoS ONE. 2013;8:e55739 pubmed publisher
Dai M, Yang Y, Shi X. Lactate dilates cochlear capillaries via type V fibrocyte-vessel coupling signaled by nNOS. Am J Physiol Heart Circ Physiol. 2011;301:H1248-54 pubmed publisher
BENDER T, Abdel Rahman A. Differential central NOS-NO signaling underlies clonidine exacerbation of ethanol-evoked behavioral impairment. Alcohol Clin Exp Res. 2010;34:555-66 pubmed publisher
Chang A, Chan J, Chan S. Differential contributions of nitric oxide synthase isoforms at hippocampal formation to negative feedback regulation of penile erection in the rat. Br J Pharmacol. 2002;136:1-8 pubmed
product information
brand :
Tocris
master code :
0546
SKU :
0546/10
product name :
L-NIO dihydrochloride
description :
NOS inhibitor
target :
eNOS Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
observed molecular weight :
246.13
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Inhibitor of nitric oxide (NO) synthase. Inhibits iNOS, eNOS and nNOS. Active in vivo .
catalog number base :
546
product keywords :
Potent eNOS inhibitors inhibits Nitric Oxide Signaling Signalling Endothelial Synthase NO Synthases eNOS iNOS nNOS 0546,
extended description :
NOS inhibitor
chemical name text :
N5-(1-Iminoethyl)-L-ornithine dihydrochloride
formula :
C 7 H 15 N 3 O 2 .2HCl
formula text :
C7H15N3O2.2HCl
cas num :
159190-44-0
2020 USD :
82
2021 USD :
86 USD
storage :
Desiccate at -20°C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK