GBR 12783 dihydrochloride | Tocris Bioscience 0513 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

GBR 12783 dihydrochloride

catalog :

0513

quantity :

10 mg (also 50 mg)

price :

139 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Matsui A, Alvarez V. Cocaine Inhibition of Synaptic Transmission in the Ventral Pallidum Is Pathway-Specific and Mediated by Serotonin. Cell Rep. 2018;23:3852-3863 pubmed publisher
Masi A, Narducci R, Landucci E, Moroni F, Mannaioni G. MPP(+) -dependent inhibition of Ih reduces spontaneous activity and enhances EPSP summation in nigral dopamine neurons. Br J Pharmacol. 2013;169:130-42 pubmed publisher
Ferreira S, Teixeira F, Garção P, Agostinho P, Ledent C, Cortes L, et al. Presynaptic CB(1) cannabinoid receptors control frontocortical serotonin and glutamate release--species differences. Neurochem Int. 2012;61:219-26 pubmed publisher
Ferraro L, Frankowska M, Marcellino D, Zaniewska M, Beggiato S, Filip M, et al. A novel mechanism of cocaine to enhance dopamine d2-like receptor mediated neurochemical and behavioral effects. An in vivo and in vitro study. Neuropsychopharmacology. 2012;37:1856-66 pubmed publisher

product information

brand :

Tocris

master code :

0513

SKU :

0513/10

product name :

GBR 12783 dihydrochloride

description :

Potent and selective DA uptake inhibitor

target :

Dopamine Transporter Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

485.5

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

A very potent and selective inhibitor of dopamine uptake (IC50 for inhibition of [3H]-dopamine uptake in rat striatal synaptosomes is 1.8 nM).

catalog number base :

513

product keywords :

Potent selective dopamine reuptake inhibitors inhibits DAT Dopamine Transporters Monoamine Neurotransmitter GBR12783 dihydrochloride Dopamine Transporters 0513,

extended description :

Potent and selective DA uptake inhibitor

chemical name text :

1-(2-Diphenylmethoxyethyl)-4-(3-phenyl-2-propenyl)-piperazine dihydrochloride

formula :

C 28 H 32 N 2 O.2HCl

formula text :

C28H32N2O.2HCl

cas num :

67469-75-4

2020 USD :

133

2021 USD :

139 USD

storage :

Desiccate at -20°C

more info or order :

Tocris Bioscience product webpage