Alrestatin | Tocris Bioscience 0485 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

Alrestatin

catalog :

0485

quantity :

10 mg (also 50 mg)

price :

101 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Mochin M, Underwood K, Cooper B, McLenithan J, Pierce A, Nalvarte C, et al. Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells. Microvasc Res. 2015;97:55-64 pubmed publisher
Bresson E, Lacroix Pepin N, Boucher Kovalik S, Chapdelaine P, Fortier M. The Prostaglandin F Synthase Activity of the Human Aldose Reductase AKR1B1 Brings New Lenses to Look at Pathologic Conditions. Front Pharmacol. 2012;3:98 pubmed publisher
Lavrentyev E, Malik K. High glucose-induced Nox1-derived superoxides downregulate PKC-betaII, which subsequently decreases ACE2 expression and ANG(1-7) formation in rat VSMCs. Am J Physiol Heart Circ Physiol. 2009;296:H106-18 pubmed publisher

product information

brand :

Tocris

master code :

0485

SKU :

0485/10

product name :

Alrestatin

description :

Aldose reductase inhibitor

target :

Aldose Reductase Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

observed molecular weight :

255.23

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Specific inhibitor of aldose reductase (IC50 = 148 M). Attenuates glucose-induced angiotensin II production in rat vascular smooth muscle in vitro .

catalog number base :

485

product keywords :

Aldose reductases inhibitors inhibits Carbohydrate Metabolism Aldose Reductase 0485,

extended description :

Aldose reductase inhibitor

chemical name text :

1,3-Dioxo-1H-benz[d,e]isoquinoline-2(3H)-acetic acid

formula :

C 14 H 9 NO 4

formula text :

C14H9NO4

cas num :

51411-04-2

2020 USD :

126

2021 USD :

101 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage