product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
0453/10
catalog :
0453/10
quantity :
10 mg (also 50 mg)
price :
168 USD
more info or order :
citations: 13
Reference
MacDonald J, Bothun A, Annis S, Sheehan H, Ray S, Gao Y, et al. A nanoscale, multi-parametric flow cytometry-based platform to study mitochondrial heterogeneity and mitochondrial DNA dynamics. Commun Biol. 2019;2:258 pubmed publisher
MacDonald J, Kura N, Sussman C, Woods D. Mitochondrial membrane depolarization enhances TRAIL-induced cell death in adult human granulosa tumor cells, KGN, through inhibition of BIRC5. J Ovarian Res. 2018;11:89 pubmed publisher
Panja D, Vedeler C, Schubert M. Paraneoplastic cerebellar degeneration: Yo antibody alters mitochondrial calcium buffering capacity. Neuropathol Appl Neurobiol. 2019;45:141-156 pubmed publisher
Rozzi S, Avdoshina V, Fields J, Mocchetti I. Human immunodeficiency virus Tat impairs mitochondrial fission in neurons. Cell Death Discov. 2018;4:8 pubmed publisher
Visavadiya N, Keasey M, Razskazovskiy V, Banerjee K, Jia C, Lovins C, et al. Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3. Cell Commun Signal. 2016;14:32 pubmed
Banh R, Iorio C, Marcotte R, Xu Y, Cojocari D, Rahman A, et al. PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia. Nat Cell Biol. 2016;18:803-813 pubmed publisher
Hogan Q, Sprick C, Guo Y, Mueller S, Bienengraeber M, Pan B, et al. Divergent effects of painful nerve injury on mitochondrial Ca(2+) buffering in axotomized and adjacent sensory neurons. Brain Res. 2014;1589:112-25 pubmed publisher
Choubey V, Cagalinec M, Liiv J, Safiulina D, Hickey M, Kuum M, et al. BECN1 is involved in the initiation of mitophagy: it facilitates PARK2 translocation to mitochondria. Autophagy. 2014;10:1105-19 pubmed publisher
Janc O, Muller M. The free radical scavenger Trolox dampens neuronal hyperexcitability, reinstates synaptic plasticity, and improves hypoxia tolerance in a mouse model of Rett syndrome. Front Cell Neurosci. 2014;8:56 pubmed publisher
Clausen A, McClanahan T, Ji S, Weiss J. Mechanisms of rapid reactive oxygen species generation in response to cytosolic Ca2+ or Zn2+ loads in cortical neurons. PLoS ONE. 2013;8:e83347 pubmed publisher
Burt R, Graves B, Gao M, Li C, Williams D, Fregoso S, et al. 9-Phenanthrol and flufenamic acid inhibit calcium oscillations in HL-1 mouse cardiomyocytes. Cell Calcium. 2013;54:193-201 pubmed publisher
Mané M, Muller M. Temporo-spectral imaging of intrinsic optical signals during hypoxia-induced spreading depression-like depolarization. PLoS ONE. 2012;7:e43981 pubmed publisher
Gerich F, Funke F, Hildebrandt B, Fasshauer M, Muller M. H(2)O(2)-mediated modulation of cytosolic signaling and organelle function in rat hippocampus. Pflugers Arch. 2009;458:937-52 pubmed publisher
product information
master code :
453
SKU :
0453/10
product name :
FCCP
unit size :
10 mg (also 50 mg)
description :
Oxidative phosphorylation uncoupler
target :
Oxidative Phosphorylation Uncouplers
category :
Small Molecules
purity :
99%
observed molecular weight :
254.17
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
FCCP is a very potent uncoupler of oxidative phosphorylation in mitochondria.
top caption :
Oxidative phosphorylation uncoupler
extended description :
Oxidative phosphorylation uncoupler
chemical name text :
Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone
formula :
C10H5F3N4O
formula text :
C10H5F3N4O
cas num :
370-86-5
USD :
168 USD
product details :
Oxidative phosphorylation uncoupler
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK