product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
0431/10
catalog :
0431/10
quantity :
10 mg
price :
199 USD
more info or order :
citations: 5
Reference
Dobson K, Jackson C, Balakrishnan S, Bellamy T. Caffeine Modulates Vesicle Release and Recovery at Cerebellar Parallel Fibre Terminals, Independently of Calcium and Cyclic AMP Signalling. PLoS ONE. 2015;10:e0125974 pubmed publisher
Kirschstein T, Protzel C, Porath K, Sellmann T, Köhling R, Hakenberg O. Age-dependent contribution of Rho kinase in carbachol-induced contraction of human detrusor smooth muscle in vitro. Acta Pharmacol Sin. 2014;35:74-81 pubmed publisher
Siddoway B, Altimimi H, Hou H, Petralia R, Xu B, Stellwagen D, et al. An essential role for inhibitor-2 regulation of protein phosphatase-1 in synaptic scaling. J Neurosci. 2013;33:11206-11 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Gruszczynska Biegala J, Pomorski P, Wisniewska M, Kuznicki J. Differential roles for STIM1 and STIM2 in store-operated calcium entry in rat neurons. PLoS ONE. 2011;6:e19285 pubmed publisher
product information
master code :
431
SKU :
0431/10
product name :
ML 9 hydrochloride
unit size :
10 mg
description :
Myosin light chain kinase inhibitor
target :
Myosin Light Chain Kinase Inhibitors
category :
Small Molecules
purity :
98%
observed molecular weight :
361.29
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
ML 9 hydrochloride is a selective MLCK inhibitor (Ki values are 4, 32 and 54 M for MLCK, PKA and PKC respectively). Also inhibits STIM1-plasma membrane interactions, preventing store-operated Ca2+ entry (SOCE).
top caption :
Myosin light chain kinase inhibitor
extended description :
Myosin light chain kinase inhibitor
chemical name text :
1-(5-Chloronaphthalenesulfonyl)homopiperazine hydrochloride
formula :
C15H17ClN2O2S.HCl
formula text :
C15H17ClN2O2S.HCl
cas num :
105637-50-1
USD :
199 USD
product details :
Myosin light chain kinase inhibitor
storage :
Desiccate at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK