product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
SKF 97541
catalog :
0379
quantity :
10 mg (also 50 mg)
price :
193 USD
more info or order :
citations: 8
Reference
Ki Y, Lim C. Sleep-promoting effects of threonine link amino acid metabolism in Drosophila neuron to GABAergic control of sleep drive. elife. 2019;8: pubmed publisher
Martelli C, Fiala A. Slow presynaptic mechanisms that mediate adaptation in the olfactory pathway of Drosophila. elife. 2019;8: pubmed publisher
Lecat Guillet N, Monnier C, Rovira X, Kniazeff J, Lamarque L, Zwier J, et al. FRET-Based Sensors Unravel Activation and Allosteric Modulation of the GABAB Receptor. Cell Chem Biol. 2017;24:360-370 pubmed publisher
Ignell R, Root C, Birse R, Wang J, Nassel D, Winther A. Presynaptic peptidergic modulation of olfactory receptor neurons in Drosophila. Proc Natl Acad Sci U S A. 2009;106:13070-5 pubmed publisher
Chen T, Cheng Y, Sun W, Shyu B. Differential regulation of morphine antinociceptive effects by endogenous enkephalinergic system in the forebrain of mice. Mol Pain. 2008;4:41 pubmed publisher
Root C, Masuyama K, Green D, Enell L, Nassel D, Lee C, et al. A presynaptic gain control mechanism fine-tunes olfactory behavior. Neuron. 2008;59:311-21 pubmed publisher
Piqueras L, Martinez V. Peripheral GABAB agonists stimulate gastric acid secretion in mice. Br J Pharmacol. 2004;142:1038-48 pubmed
Wood M, Murkitt K, Rice S, Testa T, Punia P, Stammers M, et al. The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen. Br J Pharmacol. 2000;131:1050-4 pubmed
product information
brand :
Tocris
master code :
0379
SKU :
0379/10
product name :
SKF 97541
description :
Highly potent GABAB agonist; also GABAA- antagonist
target :
GABA-B Receptor Agonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
observed molecular weight :
137.12
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Very potent GABAB agonist, at least ten times more active than baclofen (Cat. No. 0417). Also GABAA- antagonist.
catalog number base :
379
product keywords :
potent GABAB agonists GABAC antagonists Receptors SKF97541 CGP35024 CGP 35024 GABAB Receptors GABAA-rho Receptors 0379,
extended description :
Highly potent GABAB agonist; also GABAA- antagonist
chemical name text :
3-Aminopropyl(methyl)phosphinic acid
formula :
C 4 H 12 NO 2 P
formula text :
C4H12NO2P
cas num :
127729-35-5
2020 USD :
187
2021 USD :
193 USD
alt names :
CGP 35024
storage :
Desiccate at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK