product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
W-13 hydrochloride
catalog :
0361
quantity :
10 mg (also 50 mg)
price :
120 USD
more info or order :
citations: 2
Reference
Yanda M, Liu Q, Cebotaru V, Guggino W, Cebotaru L. Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca2+ in knock-out mouse models of polycystic kidney disease. J Biol Chem. 2017;292:17897-17908 pubmed publisher
Sethna F, Zhang M, Kaphzan H, Klann E, Autio D, Cox C, et al. Calmodulin activity regulates group I metabotropic glutamate receptor-mediated signal transduction and synaptic depression. J Neurosci Res. 2016;94:401-8 pubmed publisher
product information
brand :
Tocris
master code :
0361
SKU :
0361/10
product name :
W-13 hydrochloride
description :
Calmodulin antagonist
target :
Calcium Binding Protein Modulator Antagonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
349.27
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Calmodulin antagonist (inhibits calmodulin activated PDE activity with an IC50 of 68 u M). Inhibits growth of tamoxifen-resistant breast cancer cells.
catalog number base :
361
product keywords :
Calmodulin antagonists Ca2+ Binding Protein modulators Calcium Signaling Signalling W13 Calcium Binding Protein 0361,
extended description :
Calmodulin antagonist
chemical name text :
N-(4-Aminobutyl)-5-chloro-2-naphthalenesulfonamide hydrochloride
formula :
C 14 H 17 ClN 2 O 2 S.HCl
formula text :
C14H17ClN2O2S.HCl
cas num :
88519-57-7
2020 USD :
120
2021 USD :
120 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK