0348/10 | Tocris Bioscience 0348/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

0348/10

catalog :

0348/10

quantity :

10 mg (also 50 mg)

price :

211 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Kim J, Cowan A, Lisek R, Raymondi N, Rosenthal A, Hirsch D, et al. Icilin-evoked behavioral stimulation is attenuated by alpha?-adrenoceptor activation. Brain Res. 2011;1384:110-7 pubmed publisher
McDonald G, Olivieri A, Ramsay R, Holt A. On the formation and nature of the imidazoline I2 binding site on human monoamine oxidase-B. Pharmacol Res. 2010;62:475-88 pubmed publisher

product information

master code :

348

SKU :

0348/10

product name :

2-BFI hydrochloride

unit size :

10 mg (also 50 mg)

description :

Potent, selective I2 ligand. Putative agonist

target :

Imidazoline 2 (I2) Receptor Ligands

category :

Small Molecules

observed molecular weight :

222.67

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

2-BFI hydrochloride is a high affinity I2 ligand (Ki = 9.8 nM). Putative I2 agonist; potentiates morphine antinociception. Produces ipsiversive rotational behavior in rats with a full 6-OHDA lesion of the nigrostriatal tract.

top caption :

Potent, selective I2 ligand. Putative agonist

extended description :

Potent, selective I2 ligand. Putative agonist

chemical name text :

2-(2-Benzofuranyl)-2-imidazoline hydrochloride

formula :

C11H10N2O.HCl

formula text :

C11H10N2O.HCl

cas num :

89196-95-2

USD :

211 USD

product details :

Potent, selective I2 ligand. Putative agonist

storage :

Desiccate at RT

more info or order :

Tocris Bioscience product webpage