product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
0337/10
catalog :
0337/10
quantity :
10 mg (also 50 mg)
price :
356 USD
more info or order :
citations: 22
Reference
Stephen T, Higgs N, Sheehan D, Al Awabdh S, López Doménech G, Arancibia Carcamo I, et al. Miro1 Regulates Activity-Driven Positioning of Mitochondria within Astrocytic Processes Apposed to Synapses to Regulate Intracellular Calcium Signaling. J Neurosci. 2015;35:15996-6011 pubmed publisher
Rosa J, Bos R, Sack G, Fortuny C, Agarwal A, Bergles D, et al. Neuron-glia signaling in developing retina mediated by neurotransmitter spillover. elife. 2015;4: pubmed publisher
Gu Q, Yu D, Hu Z, Liu X, Yang Y, Luo Y, et al. miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement. Nat Commun. 2015;6:6789 pubmed publisher
Szokol K, Heuser K, Tang W, Jensen V, Enger R, Bedner P, et al. Augmentation of Ca(2+) signaling in astrocytic endfeet in the latent phase of temporal lobe epilepsy. Front Cell Neurosci. 2015;9:49 pubmed publisher
Nieus T, Mapelli L, D Angelo E. Regulation of output spike patterns by phasic inhibition in cerebellar granule cells. Front Cell Neurosci. 2014;8:246 pubmed publisher
Akerboom J, Chen T, Wardill T, Tian L, Marvin J, Mutlu S, et al. Optimization of a GCaMP calcium indicator for neural activity imaging. J Neurosci. 2012;32:13819-40 pubmed publisher
Platt N, Gispert S, Auburger G, Cragg S. Striatal dopamine transmission is subtly modified in human A53Tα-synuclein overexpressing mice. PLoS ONE. 2012;7:e36397 pubmed publisher
Navarrete M, Perea G, Fernandez de Sevilla D, Gomez Gonzalo M, Nunez A, Martin E, et al. Astrocytes mediate in vivo cholinergic-induced synaptic plasticity. PLoS Biol. 2012;10:e1001259 pubmed publisher
Ali A. CB1 modulation of temporally distinct synaptic facilitation among local circuit interneurons mediated by N-type calcium channels in CA1. J Neurophysiol. 2011;105:1051-62 pubmed publisher
Reissner K, Pu L, Schaffhausen J, Boyle H, Smith I, Parker I, et al. A novel postsynaptic mechanism for heterosynaptic sharing of short-term plasticity. J Neurosci. 2010;30:8797-806 pubmed publisher
Shinoda Y, Tanaka T, Tominaga Yoshino K, Ogura A. Persistent synapse loss induced by repetitive LTD in developing rat hippocampal neurons. PLoS ONE. 2010;5:e10390 pubmed publisher
Huang C, Hsu K. Activation of muscarinic acetylcholine receptors induces a nitric oxide-dependent long-term depression in rat medial prefrontal cortex. Cereb Cortex. 2010;20:982-96 pubmed publisher
Bagayogo I, Dreyfus C. Regulated release of BDNF by cortical oligodendrocytes is mediated through metabotropic glutamate receptors and the PLC pathway. ASN Neuro. 2009;1: pubmed publisher
Fukunaga I, Yeo C, Batchelor A. Potent and specific action of the mGlu1 antagonists YM-298198 and JNJ16259685 on synaptic transmission in rat cerebellar slices. Br J Pharmacol. 2007;151:870-6 pubmed
Bender V, Bender K, Brasier D, Feldman D. Two coincidence detectors for spike timing-dependent plasticity in somatosensory cortex. J Neurosci. 2006;26:4166-77 pubmed
Melis M, Perra S, Muntoni A, Pillolla G, Lutz B, Marsicano G, et al. Prefrontal cortex stimulation induces 2-arachidonoyl-glycerol-mediated suppression of excitation in dopamine neurons. J Neurosci. 2004;24:10707-15 pubmed
Melyan Z, Lancaster B, Wheal H. Metabotropic regulation of intrinsic excitability by synaptic activation of kainate receptors. J Neurosci. 2004;24:4530-4 pubmed
Kumar A, Foster T. Enhanced long-term potentiation during aging is masked by processes involving intracellular calcium stores. J Neurophysiol. 2004;91:2437-44 pubmed
Paladini C, Robinson S, Morikawa H, Williams J, Palmiter R. Dopamine controls the firing pattern of dopamine neurons via a network feedback mechanism. Proc Natl Acad Sci U S A. 2003;100:2866-71 pubmed
Matthies H, Schroeder H, Smalla K, Krug M. Enhancement of glutamate release by L-fucose changes effects of glutamate receptor antagonists on long-term potentiation in the rat hippocampus. Learn Mem. 2000;7:227-34 pubmed
Dunaevsky A, Tashiro A, Majewska A, Mason C, Yuste R. Developmental regulation of spine motility in the mammalian central nervous system. Proc Natl Acad Sci U S A. 1999;96:13438-43 pubmed
Min M, Melyan Z, Kullmann D. Synaptically released glutamate reduces gamma-aminobutyric acid (GABA)ergic inhibition in the hippocampus via kainate receptors. Proc Natl Acad Sci U S A. 1999;96:9932-7 pubmed
product information
master code :
337
SKU :
0337/10
product name :
(S)-MCPG
unit size :
10 mg (also 50 mg)
description :
Non-selective mGlu antagonist; active isomer of (RS)-MCPG (Cat. No. 0336)
target :
Group I mGluR Antagonists
category :
Small Molecules
purity :
99%
observed molecular weight :
209.2
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
( S )-MCPG is an active isomer of ( RS )-MCPG . Non-selective group I/group II metabotropic glutamate receptor antagonist. . Racemate also available.
top caption :
Non-selective mGlu antagonist; active isomer of (RS)-MCPG (Cat. No. 0336)
extended description :
Non-selective mGlu antagonist; active isomer of (RS)-MCPG (Cat. No. 0336)
chemical name text :
(S)- -Methyl-4-carboxyphenylglycine
formula :
C10H11NO4
formula text :
C10H11NO4
cas num :
150145-89-4
USD :
356 USD
product details :
Non-selective mGlu antagonist; active isomer of (RS)-MCPG (Cat. No. 0336)
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK