product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
0336/10
catalog :
0336/10
quantity :
10 mg (also 50 mg)
price :
199 USD
more info or order :
citations: 12
Reference
Scholler P, Moreno Delgado D, Lecat Guillet N, Doumazane E, Monnier C, Charrier Savournin F, et al. HTS-compatible FRET-based conformational sensors clarify membrane receptor activation. Nat Chem Biol. 2017;13:372-380 pubmed publisher
Tang W, Szokol K, Jensen V, Enger R, Trivedi C, Hvalby Ø, et al. Stimulation-evoked Ca2+ signals in astrocytic processes at hippocampal CA3-CA1 synapses of adult mice are modulated by glutamate and ATP. J Neurosci. 2015;35:3016-21 pubmed publisher
Oh W, Hill T, Zito K. Synapse-specific and size-dependent mechanisms of spine structural plasticity accompanying synaptic weakening. Proc Natl Acad Sci U S A. 2013;110:E305-12 pubmed publisher
Zhang P, Lisman J. Activity-dependent regulation of synaptic strength by PSD-95 in CA1 neurons. J Neurophysiol. 2012;107:1058-66 pubmed publisher
Tronson N, Guzman Y, Guedea A, Huh K, Gao C, Schwarz M, et al. Metabotropic glutamate receptor 5/Homer interactions underlie stress effects on fear. Biol Psychiatry. 2010;68:1007-15 pubmed publisher
Petzold G, Albeanu D, Sato T, Murthy V. Coupling of neural activity to blood flow in olfactory glomeruli is mediated by astrocytic pathways. Neuron. 2008;58:897-910 pubmed publisher
Shankar G, Li S, Mehta T, Garcia Munoz A, Shepardson N, Smith I, et al. Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory. Nat Med. 2008;14:837-42 pubmed publisher
Muddashetty R, Kelic S, Gross C, Xu M, Bassell G. Dysregulated metabotropic glutamate receptor-dependent translation of AMPA receptor and postsynaptic density-95 mRNAs at synapses in a mouse model of fragile X syndrome. J Neurosci. 2007;27:5338-48 pubmed
De Saint Jan D, Westbrook G. Disynaptic amplification of metabotropic glutamate receptor 1 responses in the olfactory bulb. J Neurosci. 2007;27:132-40 pubmed
Takayasu Y, Iino M, Shimamoto K, Tanaka K, Ozawa S. Glial glutamate transporters maintain one-to-one relationship at the climbing fiber-Purkinje cell synapse by preventing glutamate spillover. J Neurosci. 2006;26:6563-72 pubmed
Ohba S, Ikeda T, Ikegaya Y, Nishiyama N, Matsuki N, Yamada M. BDNF locally potentiates GABAergic presynaptic machineries: target-selective circuit inhibition. Cereb Cortex. 2005;15:291-8 pubmed
Zhuo M, Laitinen J, Li X, Hawkins R. On the respective roles of nitric oxide and carbon monoxide in long-term potentiation in the hippocampus. Learn Mem. 1998;5:467-80 pubmed
product information
master code :
336
SKU :
0336/10
product name :
(RS)-MCPG
unit size :
10 mg (also 50 mg)
description :
Non-selective mGlu antagonist
target :
Group I mGluR Antagonists
category :
Small Molecules
purity :
99%
observed molecular weight :
209.2
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
( RS )-MCPG is a non-selective group I/group II metabotropic glutamate receptor antagonist. . S-enantiomer and Sodium Salt also available.
top caption :
Non-selective mGlu antagonist
extended description :
Non-selective mGlu antagonist
chemical name text :
(RS)- -Methyl-4-carboxyphenylglycine
formula :
C10H11NO4
formula text :
C10H11NO4
cas num :
146669-29-6
USD :
199 USD
product details :
Non-selective mGlu antagonist
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK