product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
0323/10
catalog :
0323/10
quantity :
10 mg (also 50 mg)
price :
388 USD
more info or order :
citations: 9
Reference
Connor R, Jones L, Qiu X, Thakar J, Maggirwar S. Frontline Science: c-Myc regulates P-selectin glycoprotein ligand-1 expression in monocytes during HIV-1 infection. J Leukoc Biol. 2017;102:953-964 pubmed publisher
Riz I, Hawley T, Marsal J, Hawley R. Noncanonical SQSTM1/p62-Nrf2 pathway activation mediates proteasome inhibitor resistance in multiple myeloma cells via redox, metabolic and translational reprogramming. Oncotarget. 2016;7:66360-66385 pubmed publisher
Griffin W, Ramachandra V, Knackstedt L, Becker H. Repeated cycles of chronic intermittent ethanol exposure increases basal glutamate in the nucleus accumbens of mice without affecting glutamate transport. Front Pharmacol. 2015;6:27 pubmed publisher
Kanno H, Kawakami Z, Mizoguchi K, Ikarashi Y, Kase Y. Yokukansan, a kampo medicine, protects PC12 cells from glutamate-induced death by augmenting gene expression of cystine/glutamate antiporter system Xc-. PLoS ONE. 2014;9:e116275 pubmed publisher
Resch J, Albano R, Liu X, Hjelmhaug J, Lobner D, Baker D, et al. Augmented cystine-glutamate exchange by pituitary adenylate cyclase-activating polypeptide signaling via the VPAC1 receptor. Synapse. 2014;68:604-612 pubmed publisher
Overocker J, Pfau J. Cytokine Production Modified by System X(c)- After PM10 and Asbestos Exposure. J Young Investig. 2012;23:34-39 pubmed
Mahler S, Hensley Simon M, Tahsili Fahadan P, Lalumiere R, Thomas C, Fallon R, et al. Modafinil attenuates reinstatement of cocaine seeking: role for cystine-glutamate exchange and metabotropic glutamate receptors. Addict Biol. 2014;19:49-60 pubmed publisher
Liu R, Blower P, Pham A, Fang J, Dai Z, Wise C, et al. Cystine-glutamate transporter SLC7A11 mediates resistance to geldanamycin but not to 17-(allylamino)-17-demethoxygeldanamycin. Mol Pharmacol. 2007;72:1637-46 pubmed
Porter R, Jaeschke G, Spooren W, Ballard T, Büttelmann B, Kolczewski S, et al. Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity. J Pharmacol Exp Ther. 2005;315:711-21 pubmed
product information
master code :
323
SKU :
0323/10
product name :
(S)-4-Carboxyphenylglycine
unit size :
10 mg (also 50 mg)
description :
Competitive group I mGlu antagonist; also weak group II agonist
target :
Group I mGluR Antagonists
category :
Small Molecules
purity :
99%
observed molecular weight :
195.17
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
( S )-4-Carboxyphenylglycine is a competitive group I metabotropic glutamate receptor antagonist, with selectivity for mGlu1a/1a over mGlu5a/5b.
top caption :
Competitive group I mGlu antagonist; also weak group II agonist
extended description :
Competitive group I mGlu antagonist; also weak group II agonist
formula :
C9H9NO4
formula text :
C9H9NO4
cas num :
134052-73-6
USD :
388 USD
product details :
Competitive group I mGlu antagonist; also weak group II agonist
alt names :
( S )-4CPG
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK