product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
L-trans-2,4-PDC
catalog :
0298
quantity :
10 mg (also 50 mg)
price :
169 USD
more info or order :
citations: 4
Reference
Heinrich A, Andó R, Turi G, Rozsa B, Sperlagh B. K+ depolarization evokes ATP, adenosine and glutamate release from glia in rat hippocampus: a microelectrode biosensor study. Br J Pharmacol. 2012;167:1003-20 pubmed publisher
Yin H, Weiss J. Marked synergism between mutant SOD1 and glutamate transport inhibition in the induction of motor neuronal degeneration in spinal cord slice cultures. Brain Res. 2012;1448:153-62 pubmed publisher
Beaule C, Swanstrom A, Leone M, Herzog E. Circadian modulation of gene expression, but not glutamate uptake, in mouse and rat cortical astrocytes. PLoS ONE. 2009;4:e7476 pubmed publisher
Young K, McGehee D, Brorson J. Glutamate receptor expression and chronic glutamate toxicity in rat motor cortex. Neurobiol Dis. 2007;26:78-85 pubmed
product information
brand :
Tocris
master code :
0298
SKU :
0298/10
product name :
L-trans-2,4-PDC
description :
Transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor
target :
Glutamate (EAAT) Transporter Inhibitors
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
97%
observed molecular weight :
159.14
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Potent, competitive, transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor.
catalog number base :
298
product keywords :
potent competitive Transportable EAAT1-4 EAAT2 EAAT3 EAAT4 inhibitors inhibits non-transportable EAAT5 EAAT Excitatory Amino Acid Transporters GLAST GLT-1 Glutamate Monoamine Neurotransmitter reuptake trans-4-Carboxy-L-proline Glutamate Transporters Amino Acids 0298,
extended description :
Transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor
chemical name text :
L-trans-Pyrrolidine-2,4-dicarboxylic acid
formula :
C 6 H 9 NO 4
formula text :
C6H9NO4
cas num :
64769-66-0
2020 USD :
164
2021 USD :
169 USD
alt names :
trans -4-Carboxy- L -proline
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK