product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
(1S,3R)-ACPD
catalog :
0284
quantity :
10 mg (also 50 mg)
price :
285 USD
more info or order :
citations: 6
Reference
Scholler P, Moreno Delgado D, Lecat Guillet N, Doumazane E, Monnier C, Charrier Savournin F, et al. HTS-compatible FRET-based conformational sensors clarify membrane receptor activation. Nat Chem Biol. 2017;13:372-380 pubmed publisher
Tang W, Szokol K, Jensen V, Enger R, Trivedi C, Hvalby Ø, et al. Stimulation-evoked Ca2+ signals in astrocytic processes at hippocampal CA3-CA1 synapses of adult mice are modulated by glutamate and ATP. J Neurosci. 2015;35:3016-21 pubmed publisher
Andlauer T, Scholz Kornehl S, Tian R, Kirchner M, Babikir H, Depner H, et al. Drep-2 is a novel synaptic protein important for learning and memory. elife. 2014;3: pubmed publisher
De Pasquale R, Sherman S. A modulatory effect of the feedback from higher visual areas to V1 in the mouse. J Neurophysiol. 2013;109:2618-31 pubmed publisher
Blanco V, Stern J, Filosa J. Tone-dependent vascular responses to astrocyte-derived signals. Am J Physiol Heart Circ Physiol. 2008;294:H2855-63 pubmed publisher
Yamada R, Sasaki T, Ichikawa J, Koyama R, Matsuki N, Ikegaya Y. Long-range axonal calcium sweep induces axon retraction. J Neurosci. 2008;28:4613-8 pubmed publisher
product information
brand :
Tocris
master code :
0284
SKU :
0284/10
product name :
(1S,3R)-ACPD
description :
Group I and group II mGlu agonist; active isomer of ( )-trans-ACPD (Cat. No. 0187)
target :
Group I mGluR Agonists
category :
Small Molecules
unit size :
10 mg (also 50 mg)
purity :
98%
observed molecular weight :
173.17
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Active isomer of ( )- trans -ACPD . Agonist at both group I and II mGlu receptors (EC50 values are 5, 15, 42 and 60 M at mGluR2, mGluR5, mGluR1 and mGluR6 respectively). . NPEC-caged-(1 S ,3 R )-ACPD, ( )- trans -ACPD and cis -ACPD also available.
catalog number base :
284
product keywords :
Group II group I mGlur agonists Receptors mGlu2 mGlu3 mGluR2 mGluR3 Glutamate Metabotropic mGlu1 mGlu5 mGluR1 mGluR5 Glutamate (Metabotropic) Group I Receptors Glutamate (Metabotropic) Group II Receptors 0284,
extended description :
Group I and group II mGlu agonist; active isomer of ( )-trans-ACPD (Cat. No. 0187)
chemical name text :
(1S,3R)-1-Aminocyclopentane-1,3-dicarboxylic acid
formula :
C 7 H 11 NO 4
formula text :
C7H11NO4
cas num :
111900-32-4
2020 USD :
276
2021 USD :
285 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK