product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
(S)-AMPA
catalog :
0254
quantity :
1 mg (also 10 mg, 50 mg)
price :
125 USD
more info or order :
citations: 13
Reference
Wagner W, Lippmann K, Heisler F, Gromova K, Lombino F, Roesler M, et al. Myosin VI Drives Clathrin-Mediated AMPA Receptor Endocytosis to Facilitate Cerebellar Long-Term Depression. Cell Rep. 2019;28:11-20.e9 pubmed publisher
Gasull Camós J, Martínez Torres S, Tarrés Gatius M, Ozaita A, Artigas F, Castañé A. Serotonergic mechanisms involved in antidepressant-like responses evoked by GLT-1 blockade in rat infralimbic cortex. Neuropharmacology. 2018;139:41-51 pubmed publisher
Temkin P, Morishita W, Goswami D, Arendt K, Chen L, Malenka R. The Retromer Supports AMPA Receptor Trafficking During LTP. Neuron. 2017;94:74-82.e5 pubmed publisher
Langner E, Lemieszek M, Kwiecien J, Rajtar G, Rzeski W, Turski W. Kynurenic Acid Induces Impairment of Oligodendrocyte Viability: On the Role of Glutamatergic Mechanisms. Neurochem Res. 2017;42:838-845 pubmed publisher
Park Y, Broyles H, He S, McGrady N, Li L, Yorio T. Involvement of AMPA Receptor and Its Flip and Flop Isoforms in Retinal Ganglion Cell Death Following Oxygen/Glucose Deprivation. Invest Ophthalmol Vis Sci. 2016;57:508-26 pubmed publisher
Bell K, Al Mubarak B, Martel M, McKay S, Wheelan N, Hasel P, et al. Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2. Nat Commun. 2015;6:7066 pubmed publisher
Fairless R, Beck A, Kravchenko M, Williams S, Wissenbach U, Diem R, et al. Membrane potential measurements of isolated neurons using a voltage-sensitive dye. PLoS ONE. 2013;8:e58260 pubmed publisher
Pooler A, Phillips E, Lau D, Noble W, Hanger D. Physiological release of endogenous tau is stimulated by neuronal activity. EMBO Rep. 2013;14:389-94 pubmed publisher
Oh M, Kim J, Safaee M, Kaur G, Sun M, Kaur R, et al. Overexpression of calcium-permeable glutamate receptors in glioblastoma derived brain tumor initiating cells. PLoS ONE. 2012;7:e47846 pubmed publisher
Lussier M, Nasu Nishimura Y, Roche K. Activity-dependent ubiquitination of the AMPA receptor subunit GluA2. J Neurosci. 2011;31:3077-81 pubmed publisher
Jackson C, Welch H, Bellamy T. Control of cerebellar long-term potentiation by P-Rex-family guanine-nucleotide exchange factors and phosphoinositide 3-kinase. PLoS ONE. 2010;5:e11962 pubmed publisher
Limon A, Reyes Ruiz J, Eusebi F, Miledi R. Properties of GluR3 receptors tagged with GFP at the amino or carboxyl terminus. Proc Natl Acad Sci U S A. 2007;104:15526-30 pubmed
Underhill S, Goldberg M. Hypoxic injury of isolated axons is independent of ionotropic glutamate receptors. Neurobiol Dis. 2007;25:284-90 pubmed
product information
brand :
Tocris
master code :
0254
SKU :
0254/1
product name :
(S)-AMPA
description :
Selective AMPA agonist; active isomer of (RS)-AMPA (Cat. No. 0169)
target :
AMPA Receptor Agonists
category :
Small Molecules
unit size :
1 mg (also 10 mg, 50 mg)
purity :
99%
observed molecular weight :
186.17
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Active enantiomer of AMPA (EC50 = 3.5 u M). . NPEC-caged-( S )-AMPA, Inactive Enantiomer and Racemate also available.
catalog number base :
254
product keywords :
Selective AMPA agonists Glutamate Receptors iGluR Ionotropic AMPA Receptors 0254,
extended description :
Selective AMPA agonist; active isomer of (RS)-AMPA (Cat. No. 0169)
chemical name text :
(S)- -Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
formula :
C 7 H 10 N 2 O 4
formula text :
C7H10N2O4
cas num :
83643-88-3
2020 USD :
122
2021 USD :
125 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK