product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
0254/1
catalog :
0254/1
quantity :
1 mg (also 10 mg, 50 mg)
price :
163 USD
more info or order :
citations: 14
Reference
Wagner W, Lippmann K, Heisler F, Gromova K, Lombino F, Roesler M, et al. Myosin VI Drives Clathrin-Mediated AMPA Receptor Endocytosis to Facilitate Cerebellar Long-Term Depression. Cell Rep. 2019;28:11-20.e9 pubmed publisher
Gasull Camós J, Martínez Torres S, Tarrés Gatius M, Ozaita A, Artigas F, Castañé A. Serotonergic mechanisms involved in antidepressant-like responses evoked by GLT-1 blockade in rat infralimbic cortex. Neuropharmacology. 2018;139:41-51 pubmed publisher
Temkin P, Morishita W, Goswami D, Arendt K, Chen L, Malenka R. The Retromer Supports AMPA Receptor Trafficking During LTP. Neuron. 2017;94:74-82.e5 pubmed publisher
Langner E, Lemieszek M, Kwiecien J, Rajtar G, Rzeski W, Turski W. Kynurenic Acid Induces Impairment of Oligodendrocyte Viability: On the Role of Glutamatergic Mechanisms. Neurochem Res. 2017;42:838-845 pubmed publisher
Park Y, Broyles H, He S, McGrady N, Li L, Yorio T. Involvement of AMPA Receptor and Its Flip and Flop Isoforms in Retinal Ganglion Cell Death Following Oxygen/Glucose Deprivation. Invest Ophthalmol Vis Sci. 2016;57:508-26 pubmed publisher
Bell K, Al Mubarak B, Martel M, McKay S, Wheelan N, Hasel P, et al. Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2. Nat Commun. 2015;6:7066 pubmed publisher
Fairless R, Beck A, Kravchenko M, Williams S, Wissenbach U, Diem R, et al. Membrane potential measurements of isolated neurons using a voltage-sensitive dye. PLoS ONE. 2013;8:e58260 pubmed publisher
Pooler A, Phillips E, Lau D, Noble W, Hanger D. Physiological release of endogenous tau is stimulated by neuronal activity. EMBO Rep. 2013;14:389-94 pubmed publisher
Oh M, Kim J, Safaee M, Kaur G, Sun M, Kaur R, et al. Overexpression of calcium-permeable glutamate receptors in glioblastoma derived brain tumor initiating cells. PLoS ONE. 2012;7:e47846 pubmed publisher
Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Lussier M, Nasu Nishimura Y, Roche K. Activity-dependent ubiquitination of the AMPA receptor subunit GluA2. J Neurosci. 2011;31:3077-81 pubmed publisher
Jackson C, Welch H, Bellamy T. Control of cerebellar long-term potentiation by P-Rex-family guanine-nucleotide exchange factors and phosphoinositide 3-kinase. PLoS ONE. 2010;5:e11962 pubmed publisher
Limon A, Reyes Ruiz J, Eusebi F, Miledi R. Properties of GluR3 receptors tagged with GFP at the amino or carboxyl terminus. Proc Natl Acad Sci U S A. 2007;104:15526-30 pubmed
Underhill S, Goldberg M. Hypoxic injury of isolated axons is independent of ionotropic glutamate receptors. Neurobiol Dis. 2007;25:284-90 pubmed
product information
master code :
254
SKU :
0254/1
product name :
(S)-AMPA
unit size :
1 mg (also 10 mg, 50 mg)
description :
Selective AMPA agonist; active isomer of (RS)-AMPA (Cat. No. 0169)
target :
AMPA Receptor Agonists
category :
Small Molecules
purity :
99%
observed molecular weight :
186.17
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
( S )-AMPA is an active enantiomer of AMPA (EC50 = 3.5 u M). . NPEC-caged-( S )-AMPA, Inactive Enantiomer and Racemate also available.
top caption :
Selective AMPA agonist; active isomer of (RS)-AMPA (Cat. No. 0169)
extended description :
Selective AMPA agonist; active isomer of (RS)-AMPA (Cat. No. 0169)
chemical name text :
(S)- -Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid
formula :
C7H10N2O4
formula text :
C7H10N2O4
cas num :
83643-88-3
USD :
163 USD
product details :
Selective AMPA agonist; active isomer of (RS)-AMPA (Cat. No. 0169)
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK