product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
0246/10
catalog :
0246/10
quantity :
10 mg (also 50 mg)
price :
271 USD
more info or order :
citations: 13
Reference |
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Ying S, Goldstein P. Propofol suppresses synaptic responsiveness of somatosensory relay neurons to excitatory input by potentiating GABA(A) receptor chloride channels. Mol Pain. 2005;1:2 pubmed
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Ohba S, Ikeda T, Ikegaya Y, Nishiyama N, Matsuki N, Yamada M. BDNF locally potentiates GABAergic presynaptic machineries: target-selective circuit inhibition. Cereb Cortex. 2005;15:291-8 pubmed
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Melyan Z, Lancaster B, Wheal H. Metabotropic regulation of intrinsic excitability by synaptic activation of kainate receptors. J Neurosci. 2004;24:4530-4 pubmed
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Piet R, Vargova L, Sykova E, Poulain D, Oliet S. Physiological contribution of the astrocytic environment of neurons to intersynaptic crosstalk. Proc Natl Acad Sci U S A. 2004;101:2151-5 pubmed
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Wood M, Murkitt K, Rice S, Testa T, Punia P, Stammers M, et al. The human GABA(B1b) and GABA(B2) heterodimeric recombinant receptor shows low sensitivity to phaclofen and saclofen. Br J Pharmacol. 2000;131:1050-4 pubmed
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image
image 1 :

Cat.No. 0246 - Saclofen C9H12ClNO3S CAS No. 125464-42-8
product information
master code :
246
SKU :
0246/10
product name :
Saclofen
unit size :
10 mg (also 50 mg)
description :
Selective GABAB antagonist
target :
GABA-B Receptor Antagonists
category :
Small Molecules
purity :
99%
observed molecular weight :
249.72
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
Saclofen is a selective antagonist at GABAB receptors.
top caption :
Selective GABAB antagonist
extended description :
Selective GABAB antagonist
chemical name text :
(RS)-3-Amino-2-(4-chlorophenyl)propylsulfonic acid
formula :
C9H12ClNO3S
formula text :
C9H12ClNO3S
cas num :
125464-42-8
USD :
271 USD
product details :
Selective GABAB antagonist
storage :
Store at RT
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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