7-Chlorokynurenic acid | Tocris Bioscience 0237 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

7-Chlorokynurenic acid

catalog :

0237

quantity :

10 mg (also 50 mg)

price :

86 USD

more info or order :

Tocris Bioscience product webpage

citations: 5

Reference
De Biase L, Kang S, Baxi E, Fukaya M, Pucak M, Mishina M, et al. NMDA receptor signaling in oligodendrocyte progenitors is not required for oligodendrogenesis and myelination. J Neurosci. 2011;31:12650-62 pubmed publisher
Baltan S, Besancon E, Mbow B, Ye Z, Hamner M, Ransom B. White matter vulnerability to ischemic injury increases with age because of enhanced excitotoxicity. J Neurosci. 2008;28:1479-89 pubmed publisher
Vigot R, Barbieri S, Brauner Osborne H, Turecek R, Shigemoto R, Zhang Y, et al. Differential compartmentalization and distinct functions of GABAB receptor variants. Neuron. 2006;50:589-601 pubmed
Shin H, Dunn A, Jones P, Boas D, Moskowitz M, Ayata C. Vasoconstrictive neurovascular coupling during focal ischemic depolarizations. J Cereb Blood Flow Metab. 2006;26:1018-30 pubmed
Casado M, Dieudonne S, Ascher P. Presynaptic N-methyl-D-aspartate receptors at the parallel fiber-Purkinje cell synapse. Proc Natl Acad Sci U S A. 2000;97:11593-7 pubmed

product information

brand :

Tocris

master code :

0237

SKU :

0237/10

product name :

7-Chlorokynurenic acid

description :

Potent competitive inhibitor of L-glutamate uptake

target :

Glutamate (EAAT) Transporter Inhibitors

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

98%

observed molecular weight :

223.62

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NMDA receptor antagonist acting at the glycine site. Potent competitive inhibitor of L-glutamate transport into synaptic vesicles. . Sodium Salt also available.

catalog number base :

237

product keywords :

Potent competitive inhibitors inhibits L-glutamate uptake NMDA antagonists glycine site EAAT Excitatory Amino Acid Transporters GLAST GLT-1 Glutamate Monoamine Neurotransmitter Receptors N-Methyl-D-Aspartate iGluR Ionotropic Glutamate Transporters NMDA Receptors 0237,

extended description :

Potent competitive inhibitor of L-glutamate uptake

chemical name text :

7-Chloro-4-hydroxyquinoline-2-carboxylic acid

formula :

C 10 H 6 ClNO 3

formula text :

C10H6ClNO3

cas num :

18000-24-3

2020 USD :

2021 USD :

86 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage