product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
Glycine
catalog :
0219
quantity :
1 g
price :
63 USD
more info or order :
citations: 4
Reference
Hangen E, Cordelières F, Petersen J, Choquet D, Coussen F. Neuronal Activity and Intracellular Calcium Levels Regulate Intracellular Transport of Newly Synthesized AMPAR. Cell Rep. 2018;24:1001-1012.e3 pubmed publisher
Sivakumaran S, Cardarelli R, Maguire J, Kelley M, Silayeva L, Morrow D, et al. Selective inhibition of KCC2 leads to hyperexcitability and epileptiform discharges in hippocampal slices and in vivo. J Neurosci. 2015;35:8291-6 pubmed publisher
Kenny A, Cousins S, Pinho L, Stephenson F. The integrity of the glycine co-agonist binding site of N-methyl-D-aspartate receptors is a functional quality control checkpoint for cell surface delivery. J Biol Chem. 2009;284:324-33 pubmed publisher
Kaushal V, Schlichter L. Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra. J Neurosci. 2008;28:2221-30 pubmed publisher
product information
brand :
Tocris
master code :
0219
SKU :
0219/1G
product name :
Glycine
description :
Endogenous potentiator of NMDA receptors
target :
Additional NMDA Receptor Compounds
category :
Small Molecules
unit size :
1 g
observed molecular weight :
75.07
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
One of the major inhibitory neurotransmitters in the mammalian CNS, predominantly active in the spinal cord and brain stem. Also acts as a modulator of excitatory amino acid transmission mediated by NMDA receptors.
catalog number base :
219
product keywords :
Endogenous glycine receptor agonists potentiator co-transmitter GlyR Glycine Receptors Glutamate NMDA N-Methyl-D-Aspartate iGluR Ionotropic NMDA Receptors Glycine Receptors 0219,
extended description :
Endogenous potentiator of NMDA receptors
chemical name text :
Aminoethanoic acid
formula :
C 2 H 5 NO 2
formula text :
C2H5NO2
cas num :
56-40-6
2020 USD :
61
2021 USD :
63 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK