product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
L-Glutamic acid
catalog :
0218
quantity :
1 g
price :
65 USD
more info or order :
citations: 8
Reference
Falcucci R, Wertz R, Green J, Meucci O, Salvino J, Fontana A. Novel Positive Allosteric Modulators of Glutamate Transport Have Neuroprotective Properties in an in Vitro Excitotoxic Model. ACS Chem Neurosci. 2019;10:3437-3453 pubmed publisher
Schitine C, Méndez Flores O, Santos L, Ornelas I, Calaza K, Pérez Toledo K, et al. Functional plasticity of GAT-3 in avian Müller cells is regulated by neurons via a glutamatergic input. Neurochem Int. 2015;82:42-51 pubmed publisher
Moreno J, Muguruza C, Umali A, Mortillo S, Holloway T, Pilar Cuéllar F, et al. Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5-HT2A·mGlu2) receptor heteromerization and its psychoactive behavioral function. J Biol Chem. 2012;287:44301-19 pubmed publisher
Owaisat S, Raffa R, Rawls S. In vivo comparison of harmine efficacy against psychostimulants: preferential inhibition of the cocaine response through a glutamatergic mechanism. Neurosci Lett. 2012;525:12-6 pubmed publisher
Tallarida C, Song K, Raffa R, Rawls S. Glutamate carboxypeptidase II (GCPII) inhibitor displays anti-glutamate and anti-cocaine effects in an invertebrate assay. Amino Acids. 2012;42:2521-4 pubmed publisher
Moreno J, Kurita M, Holloway T, Lopez J, Cadagan R, Martinez Sobrido L, et al. Maternal influenza viral infection causes schizophrenia-like alterations of 5-HT?A and mGlu? receptors in the adult offspring. J Neurosci. 2011;31:1863-72 pubmed publisher
Galici R, Jones C, Hemstapat K, Nong Y, Echemendia N, Williams L, et al. Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice. J Pharmacol Exp Ther. 2006;318:173-85 pubmed
Calo L, Bruno V, Spinsanti P, Molinari G, Korkhov V, Esposito Z, et al. Interactions between ephrin-B and metabotropic glutamate 1 receptors in brain tissue and cultured neurons. J Neurosci. 2005;25:2245-54 pubmed
product information
brand :
Tocris
master code :
0218
SKU :
0218/1G
product name :
L-Glutamic acid
description :
Endogenous, non-selective glutamate receptor agonist
target :
Non-selective mGluR Agonists
category :
Small Molecules
unit size :
1 g
observed molecular weight :
147.13
url print :
?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
The predominant excitatory transmitter in the mammalian central nervous system. Acts at ionotropic and metabotropic glutamate receptors. . MNI-caged-L-glutamate and D-isomer also available.
catalog number base :
218
product keywords :
Endogenous non-selective agonists Glutamate Ionotropic Non-Selective iGluR Receptors mGlur Metabotropic Non-selective Ionotropic Glutamate Non-selective mGlu Ferroptosis Amino Acids 0218,
extended description :
Endogenous, non-selective glutamate receptor agonist
chemical name text :
(S)-1-Aminopropane-1,3-dicarboxylic acid
formula :
C 5 H 9 NO 4
formula text :
C5H9NO4
cas num :
56-86-0
2020 USD :
62
2021 USD :
65 USD
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK