product summary
Loading...
company name :
Tocris Bioscience
product type :
chemical
product name :
0218/1G
catalog :
0218/1G
quantity :
1 g
price :
83 USD
more info or order :
citations: 9
Reference
Kopach O, Rusakov D, Sylantyev S. Multi-target action of β-alanine protects cerebellar tissue from ischemic damage. Cell Death Dis. 2022;13:747 pubmed publisher
Falcucci R, Wertz R, Green J, Meucci O, Salvino J, Fontana A. Novel Positive Allosteric Modulators of Glutamate Transport Have Neuroprotective Properties in an in Vitro Excitotoxic Model. ACS Chem Neurosci. 2019;10:3437-3453 pubmed publisher
Schitine C, Méndez Flores O, Santos L, Ornelas I, Calaza K, Pérez Toledo K, et al. Functional plasticity of GAT-3 in avian Müller cells is regulated by neurons via a glutamatergic input. Neurochem Int. 2015;82:42-51 pubmed publisher
Moreno J, Muguruza C, Umali A, Mortillo S, Holloway T, Pilar Cuéllar F, et al. Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5-HT2A·mGlu2) receptor heteromerization and its psychoactive behavioral function. J Biol Chem. 2012;287:44301-19 pubmed publisher
Owaisat S, Raffa R, Rawls S. In vivo comparison of harmine efficacy against psychostimulants: preferential inhibition of the cocaine response through a glutamatergic mechanism. Neurosci Lett. 2012;525:12-6 pubmed publisher
Tallarida C, Song K, Raffa R, Rawls S. Glutamate carboxypeptidase II (GCPII) inhibitor displays anti-glutamate and anti-cocaine effects in an invertebrate assay. Amino Acids. 2012;42:2521-4 pubmed publisher
Moreno J, Kurita M, Holloway T, Lopez J, Cadagan R, Martinez Sobrido L, et al. Maternal influenza viral infection causes schizophrenia-like alterations of 5-HT?A and mGlu? receptors in the adult offspring. J Neurosci. 2011;31:1863-72 pubmed publisher
Galici R, Jones C, Hemstapat K, Nong Y, Echemendia N, Williams L, et al. Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice. J Pharmacol Exp Ther. 2006;318:173-85 pubmed
Calo L, Bruno V, Spinsanti P, Molinari G, Korkhov V, Esposito Z, et al. Interactions between ephrin-B and metabotropic glutamate 1 receptors in brain tissue and cultured neurons. J Neurosci. 2005;25:2245-54 pubmed
product information
master code :
218
SKU :
0218/1G
product name :
L-Glutamic acid
unit size :
1 g
description :
Endogenous, non-selective glutamate receptor agonist
target :
Non-selective mGluR Agonists
category :
Small Molecules
observed molecular weight :
147.13
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
L-Glutamic acid is a the predominant excitatory transmitter in the mammalian central nervous system. L-Glutamic acid acts at ionotropic and metabotropic glutamate receptors. . MNI-caged-L-glutamate (Cat. No. 1490) also available.
top caption :
Endogenous, non-selective glutamate receptor agonist
extended description :
Endogenous, non-selective glutamate receptor agonist
chemical name text :
(S)-1-Aminopropane-1,3-dicarboxylic acid
formula :
C5H9NO4
formula text :
C5H9NO4
cas num :
56-86-0
USD :
83 USD
product details :
Endogenous, non-selective glutamate receptor agonist
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK