L-Quisqualic acid | Tocris Bioscience 0188 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

L-Quisqualic acid

catalog :

0188

quantity :

1 mg (also 10 mg, 50 mg)

price :

103 USD

more info or order :

Tocris Bioscience product webpage

citations: 9

Reference
Shin S, Jeong B, Wall B, Li J, Shan N, Wen Y, et al. Participation of xCT in melanoma cell proliferation in vitro and tumorigenesis in vivo. Oncogenesis. 2018;7:86 pubmed publisher
Scholler P, Moreno Delgado D, Lecat Guillet N, Doumazane E, Monnier C, Charrier Savournin F, et al. HTS-compatible FRET-based conformational sensors clarify membrane receptor activation. Nat Chem Biol. 2017;13:372-380 pubmed publisher
Hu Z, Tu J. The roads to mitochondrial dysfunction in a rat model of posttraumatic syringomyelia. Biomed Res Int. 2015;2015:831490 pubmed publisher
El Mansari M, Lecours M, Blier P. Effects of acute and sustained administration of vortioxetine on the serotonin system in the hippocampus: electrophysiological studies in the rat brain. Psychopharmacology (Berl). 2015;232:2343-52 pubmed publisher
El Mansari M, Manta S, Oosterhof C, El Iskandrani K, Chenu F, Shim S, et al. Restoration of serotonin neuronal firing following long-term administration of bupropion but not paroxetine in olfactory bulbectomized rats. Int J Neuropsychopharmacol. 2014;18: pubmed publisher
Wall B, Wangari Talbot J, Shin S, Schiff D, Sierra J, Yu L, et al. Disruption of GRM1-mediated signalling using riluzole results in DNA damage in melanoma cells. Pigment Cell Melanoma Res. 2014;27:263-74 pubmed publisher
Porter R, Jaeschke G, Spooren W, Ballard T, Büttelmann B, Kolczewski S, et al. Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity. J Pharmacol Exp Ther. 2005;315:711-21 pubmed
Calo L, Bruno V, Spinsanti P, Molinari G, Korkhov V, Esposito Z, et al. Interactions between ephrin-B and metabotropic glutamate 1 receptors in brain tissue and cultured neurons. J Neurosci. 2005;25:2245-54 pubmed
Ferre S, Karcz Kubicha M, Hope B, Popoli P, Burgueno J, Gutiérrez M, et al. Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: implications for striatal neuronal function. Proc Natl Acad Sci U S A. 2002;99:11940-5 pubmed

product information

brand :

Tocris

master code :

0188

SKU :

0188/1

product name :

L-Quisqualic acid

description :

AMPA agonist; also group I mGlu agonist

target :

AMPA Receptor Agonists

category :

Small Molecules

unit size :

1 mg (also 10 mg, 50 mg)

purity :

99%

observed molecular weight :

189.13

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

Glutamate receptor agonist acting at AMPA receptors and metabotropic glutamate receptors positively linked to phosphoinositide hydrolysis. Sensitizes neurons in hippocampus to depolarization by L-AP6 (the so called quis effect). Also available as part of the Group I mGlu Receptor Tocriset .

catalog number base :

188

product keywords :

AMPA group I mGlur agonists potent Glutamate Receptors iGlur Ionotropic Group mGlu1 mGlu5 mGluR1 mGluR5 Metabotropic AMPA Receptors Glutamate (Metabotropic) Group I Receptors 0188,

extended description :

AMPA agonist; also group I mGlu agonist

chemical name text :

(L)-(+)- -Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid

formula :

C 5 H 7 N 3 O 5

formula text :

C5H7N3O5

cas num :

52809-07-1

2020 USD :

2021 USD :

103 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage