product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
0188/1
catalog :
0188/1
quantity :
1 mg (also 10 mg, 50 mg)
price :
133 USD
more info or order :
citations: 11
Reference |
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Porter R, Jaeschke G, Spooren W, Ballard T, Büttelmann B, Kolczewski S, et al. Fenobam: a clinically validated nonbenzodiazepine anxiolytic is a potent, selective, and noncompetitive mGlu5 receptor antagonist with inverse agonist activity. J Pharmacol Exp Ther. 2005;315:711-21 pubmed
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Calo L, Bruno V, Spinsanti P, Molinari G, Korkhov V, Esposito Z, et al. Interactions between ephrin-B and metabotropic glutamate 1 receptors in brain tissue and cultured neurons. J Neurosci. 2005;25:2245-54 pubmed
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Ferre S, Karcz Kubicha M, Hope B, Popoli P, Burgueno J, Gutiérrez M, et al. Synergistic interaction between adenosine A2A and glutamate mGlu5 receptors: implications for striatal neuronal function. Proc Natl Acad Sci U S A. 2002;99:11940-5 pubmed
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product information
master code :
188
SKU :
0188/1
product name :
L-Quisqualic acid
unit size :
1 mg (also 10 mg, 50 mg)
description :
AMPA agonist; also group I mGlu agonist
target :
AMPA Receptor Agonists
category :
Small Molecules
purity :
99%
observed molecular weight :
189.13
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
L-Quisqualic acid is a glutamate receptor agonist acting at AMPA receptors and metabotropic glutamate receptors positively linked to phosphoinositide hydrolysis. L-Quisqualic acid sensitizes neurons in hippocampus to depolarization by L-AP6 (the so called quis effect).
top caption :
AMPA agonist; also group I mGlu agonist
extended description :
AMPA agonist; also group I mGlu agonist
chemical name text :
(L)-(+)- -Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid
formula :
C5H7N3O5
formula text :
C5H7N3O5
cas num :
52809-07-1
USD :
133 USD
product details :
AMPA agonist; also group I mGlu agonist
storage :
Store at RT
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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