0187/10 | Tocris Bioscience 0187/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

0187/10

catalog :

0187/10

quantity :

10 mg (also 50 mg)

price :

267 USD

more info or order :

Tocris Bioscience product webpage

citations: 7

Reference
Rojas A, Wetherington J, Shaw R, Serrano G, Swanger S, Dingledine R. Activation of group I metabotropic glutamate receptors potentiates heteromeric kainate receptors. Mol Pharmacol. 2013;83:106-21 pubmed publisher
Coulon P, Kanyshkova T, Broicher T, Munsch T, Wettschureck N, Seidenbecher T, et al. Activity Modes in Thalamocortical Relay Neurons are Modulated by G(q)/G(11) Family G-proteins - Serotonergic and Glutamatergic Signaling. Front Cell Neurosci. 2010;4:132 pubmed publisher
Young A, Sun Q. Long-term modifications in the strength of excitatory associative inputs in the piriform cortex. Chem Senses. 2007;32:783-94 pubmed
Newman E. Calcium increases in retinal glial cells evoked by light-induced neuronal activity. J Neurosci. 2005;25:5502-10 pubmed
Ying S, Goldstein P. Propofol suppresses synaptic responsiveness of somatosensory relay neurons to excitatory input by potentiating GABA(A) receptor chloride channels. Mol Pain. 2005;1:2 pubmed
Nishi A, Liu F, Matsuyama S, Hamada M, Higashi H, Nairn A, et al. Metabotropic mGlu5 receptors regulate adenosine A2A receptor signaling. Proc Natl Acad Sci U S A. 2003;100:1322-7 pubmed
Fujino K, Oertel D. Bidirectional synaptic plasticity in the cerebellum-like mammalian dorsal cochlear nucleus. Proc Natl Acad Sci U S A. 2003;100:265-70 pubmed

image

image 1 :

Cat.No. 0187 - trans-ACPD C7H11NO4 CAS No. 67684-64-4

product information

master code :

187

SKU :

0187/10

product name :

trans-ACPD

unit size :

10 mg (also 50 mg)

description :

Group I and II mGlu agonist

target :

Group I mGluR Agonists

category :

Small Molecules

purity :

99%

observed molecular weight :

173.17

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

( )- trans -ACPD is an equimolecular mixture of (1S,3R)- and (1R,3S)-ACPD. Selective agonist for metabotropic glutamate receptors; active at both group I and group II mGlu receptors (EC50 values are 2, 15, 23 and ~800 M at mGluR2, mGluR1, mGluR5 and mGluR4 respectively). . (1 S ,3 R )-ACPD and cis -ACPD also available.

top caption :

Group I and II mGlu agonist

extended description :

Group I and II mGlu agonist

chemical name text :

( )-1-Aminocyclopentane-trans-1,3-dicarboxylic acid

formula :

C7H11NO4

formula text :

C7H11NO4

cas num :

67684-64-4

USD :

267 USD

product details :

Group I and II mGlu agonist

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage