0183/10 | Tocris Bioscience 0183/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

0183/10

catalog :

0183/10

quantity :

10 mg

price :

276 USD

more info or order :

Tocris Bioscience product webpage

citations: 1

Reference
Nakade Y, Iwata Y, Furuichi K, Mita M, Hamase K, Konno R, et al. Gut microbiota-derived D-serine protects against acute kidney injury. JCI Insight. 2018;3: pubmed publisher

product information

master code :

183

SKU :

0183/10

product name :

L-(-)-threo-3-Hydroxyaspartic acid

unit size :

10 mg

description :

Transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor

target :

Glutamate (EAAT) Transporter Inhibitors

category :

Small Molecules

purity :

98%

observed molecular weight :

149.1

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

L-(-)- threo -3-Hydroxyaspartic acid is a potent, competitive, transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor. In [3H]-d-Asp uptake assays in HEK293 cells expressing human EAAT1, EAAT2 and EAAT3, Ki values are 11, 19, and 14 M, respectively. In a FLIPR Membrane Potential (FMP) assay, Km values are 3.6, 3.8 and 3.2 M for human EAAT1, EAAT2 and EAAT3, respectively.

top caption :

Transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor

extended description :

Transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor

formula :

C4H7NO5

formula text :

C4H7NO5

cas num :

7298-99-9

USD :

276 USD

product details :

Transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor

alt names :

L- threo - -Hydroxyaspartic acid

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage