product summary
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company name :
Tocris Bioscience
product type :
chemical
product name :
0131/10
catalog :
0131/10
quantity :
10 mg (also 50 mg)
price :
165 USD
more info or order :
citations: 25
Reference |
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Nateri A, Raivich G, Gebhardt C, Da Costa C, Naumann H, Vreugdenhil M, et al. ERK activation causes epilepsy by stimulating NMDA receptor activity. EMBO J. 2007;26:4891-901 pubmed
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Kelm M, Criswell H, Breese G. Calcium release from presynaptic internal stores is required for ethanol to increase spontaneous gamma-aminobutyric acid release onto cerebellum Purkinje neurons. J Pharmacol Exp Ther. 2007;323:356-64 pubmed
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Woo R, Li X, Tao Y, Carpenter Hyland E, Huang Y, Weber J, et al. Neuregulin-1 enhances depolarization-induced GABA release. Neuron. 2007;54:599-610 pubmed
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Shao M, Hirsch J, Giaume C, Peusner K. Spontaneous synaptic activity is primarily GABAergic in vestibular nucleus neurons of the chick embryo. J Neurophysiol. 2003;90:1182-92 pubmed
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Vida I, Frotscher M. A hippocampal interneuron associated with the mossy fiber system. Proc Natl Acad Sci U S A. 2000;97:1275-80 pubmed
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product information
master code :
131
SKU :
0131/10
product name :
(-)-Bicuculline methochloride
unit size :
10 mg (also 50 mg)
description :
GABAA antagonist; more water soluble version of (+)-bicuculline (Cat. No. 0130)
target :
GABA-A Receptor Antagonists
category :
Small Molecules
purity :
99%
observed molecular weight :
417.85
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
(-)-Bicuculline methochloride is a methochloride salt of (+)-bicuculline . Water soluble and more stable than bicuculline. Non-GABA receptor-mediated actions reported. . Methoiodide Salt and Methobromide Salt also available.
top caption :
GABAA antagonist; more water soluble version of (+)-bicuculline (Cat. No. 0130)
extended description :
GABAA antagonist; more water soluble version of (+)-bicuculline (Cat. No. 0130)
chemical name text :
[R-(R*,S*)]-5-(6,8-Dihydro-8-oxofuro[3,4-e]-1,3-benzodioxol-6-yl)-5,6,7,8-tetrahydro-6,6-dimethyl-1,3-dioxolo[4,5-g]isoquinolinium chloride
formula :
C21H20ClNO6
formula text :
C21H20ClNO6
cas num :
38641-83-7
USD :
165 USD
product details :
GABAA antagonist; more water soluble version of (+)-bicuculline (Cat. No. 0130)
storage :
Store at RT
more info or order :
company information

Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com800-343-7475
headquarters: UK
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