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company name :
Tocris Bioscience
product type :
chemical
product name :
0130/50
catalog :
0130/50
quantity :
50 mg
price :
281 USD
more info or order :
citations: 101
Reference
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Yamamoto Y, Lee D, Kim Y, Lee B, Seo C, Kawasaki H, et al. Raf kinase inhibitory protein is required for cerebellar long-term synaptic depression by mediating PKC-dependent MAPK activation. J Neurosci. 2012;32:14254-64 pubmed publisher
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Fox J, Sakamuru S, Huang R, Teneva N, Simmons S, Xia M, et al. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proc Natl Acad Sci U S A. 2012;109:5423-8 pubmed publisher
Jiang E, Yan X, Weng H. Glial glutamate transporter and glutamine synthetase regulate GABAergic synaptic strength in the spinal dorsal horn. J Neurochem. 2012;121:526-36 pubmed publisher
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Zhu L, Sacco T, Strata P, Sacchetti B. Basolateral amygdala inactivation impairs learning-induced long-term potentiation in the cerebellar cortex. PLoS ONE. 2011;6:e16673 pubmed publisher
Mou L, Heldt S, Ressler K. Rapid brain-derived neurotrophic factor-dependent sequestration of amygdala and hippocampal GABA(A) receptors via different tyrosine receptor kinase B-mediated phosphorylation pathways. Neuroscience. 2011;176:72-85 pubmed publisher
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Smejkalova T, Woolley C. Estradiol acutely potentiates hippocampal excitatory synaptic transmission through a presynaptic mechanism. J Neurosci. 2010;30:16137-48 pubmed publisher
Yue L, Xie A, Bruzik K, Frølund B, Qian H, Pepperberg D. Potentiating action of propofol at GABAA receptors of retinal bipolar cells. Invest Ophthalmol Vis Sci. 2011;52:2497-509 pubmed publisher
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product information
master code :
130
SKU :
0130/50
product name :
(+)-Bicuculline
unit size :
50 mg
description :
Potent GABAA antagonist
target :
GABA-A Receptor Antagonists
category :
Small Molecules
purity :
99%
observed molecular weight :
367.36
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
(+)-Bicuculline is a classical GABAA antagonist. . Methoiodide Salt, Methobromide Salt and Methochloride Salt also available.
top caption :
Potent GABAA antagonist
extended description :
Potent GABAA antagonist
chemical name text :
[R-(R*,S*)]-6-(5,6,7,8-Tetrahydro-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)furo[3,4-e]-1,3-benzodioxol-8(6H)-one
formula :
C20H17NO6
formula text :
C20H17NO6
cas num :
485-49-4
USD :
281 USD
product details :
Potent GABAA antagonist
storage :
Store at +4░C
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK