L-AP5 | Tocris Bioscience 0107 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

L-AP5

catalog :

0107

quantity :

10 mg (also 50 mg)

price :

223 USD

more info or order :

Tocris Bioscience product webpage

citations: 3

Reference
Fan J, Stemkowski P, Gandini M, Black S, Zhang Z, Souza I, et al. Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP(-/-) Mice. Front Cell Neurosci. 2016;10:74 pubmed publisher
Kinney G. GAT-3 transporters regulate inhibition in the neocortex. J Neurophysiol. 2005;94:4533-7 pubmed
Fernandez Monreal M, Lopez Atalaya J, Benchenane K, Cacquevel M, Dulin F, Le Caer J, et al. Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling. J Biol Chem. 2004;279:50850-6 pubmed

product information

brand :

Tocris

master code :

0107

SKU :

0107/10

product name :

L-AP5

description :

Potent and selective NMDA antagonist; less active form of DL-AP5

target :

NMDA Receptor Antagonists

category :

Small Molecules

unit size :

10 mg (also 50 mg)

purity :

99%

observed molecular weight :

197.13

url print :

?utm_source=distributor&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

NMDA antagonist. Also agonist at quisqualate-sensitized AP6 site, where it is more potent than the isomer D-AP5 . . DL Mixture and D-isomer also available.

catalog number base :

107

product keywords :

Glutamate NMDA Receptors N-Methyl-D-Aspartate iGlu Ionotropic L-APV LAPV L_APV NMDA Receptors 0107,

extended description :

Potent and selective NMDA antagonist; less active form of DL-AP5

chemical name text :

L-(+)-2-Amino-5-phosphonopentanoic acid

formula :

C 5 H 12 NO 5 P

formula text :

C5H12NO5P

cas num :

79055-67-7

2020 USD :

218

2021 USD :

223 USD

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage