0107/10 | Tocris Bioscience 0107/10 product information

product summary

company name :

Tocris Bioscience

product type :

chemical

product name :

0107/10

catalog :

0107/10

quantity :

10 mg (also 50 mg)

price :

281 USD

more info or order :

Tocris Bioscience product webpage

citations: 4

Reference
Fan J, Stemkowski P, Gandini M, Black S, Zhang Z, Souza I, et al. Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP(-/-) Mice. Front Cell Neurosci. 2016;10:74 pubmed publisher
Tozzi A, de Iure A, Di Filippo M, Costa C, Caproni S, Pisani A, et al. Critical role of calcitonin gene-related peptide receptors in cortical spreading depression. Proc Natl Acad Sci U S A. 2012;109:18985-90 pubmed publisher
Kinney G. GAT-3 transporters regulate inhibition in the neocortex. J Neurophysiol. 2005;94:4533-7 pubmed
Fernandez Monreal M, Lopez Atalaya J, Benchenane K, Cacquevel M, Dulin F, Le Caer J, et al. Arginine 260 of the amino-terminal domain of NR1 subunit is critical for tissue-type plasminogen activator-mediated enhancement of N-methyl-D-aspartate receptor signaling. J Biol Chem. 2004;279:50850-6 pubmed

product information

master code :

107

SKU :

0107/10

product name :

L-AP5

unit size :

10 mg (also 50 mg)

description :

Potent and selective NMDA antagonist; less active form of DL-AP5

target :

NMDA Receptor Antagonists

category :

Small Molecules

purity :

99%

observed molecular weight :

197.13

url print :

?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules

details of functionality :

L-AP5 is an NMDA antagonist and an agonist at quisqualate-sensitized AP6 site, where it is more potent than the isomer D-AP5. L-AP5 is more potent than D-AP5 at depressing synaptic responses at amino acid-induced and synaptic excitation of cat spinal neurons. . D-isomer, DL mixture and sodium salt also available.

top caption :

Potent and selective NMDA antagonist; less active form of DL-AP5

extended description :

Potent and selective NMDA antagonist; less active form of DL-AP5

chemical name text :

L-(+)-2-Amino-5-phosphonopentanoic acid

formula :

C5H12NO5P

formula text :

C5H12NO5P

cas num :

79055-67-7

USD :

281 USD

product details :

Potent and selective NMDA antagonist; less active form of DL-AP5

storage :

Store at RT

more info or order :

Tocris Bioscience product webpage