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company name :
Tocris Bioscience
product type :
chemical
product name :
0106/1
catalog :
0106/1
quantity :
1 mg (also 10 mg, 50 mg, 100 mg)
price :
103 USD
more info or order :
citations: 381
Reference
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product information
master code :
106
SKU :
0106/1
product name :
D-AP5
unit size :
1 mg (also 10 mg, 50 mg, 100 mg)
description :
Potent and selective NMDA receptor antagonist; more active form of DL-AP5
target :
NMDA Receptor Antagonists
category :
Small Molecules
purity :
99%
observed molecular weight :
197.13
url print :
?utm_source=labome&utm_medium=referral&utm_campaign=product&utm_term=smallmolecules
details of functionality :
D-AP5 is a selective NMDA receptor antagonist that competes with glutamate binding and is commonly used to inhibit NMDA-dependent synaptic plasticity. D-AP5 is the more active isomer of DL-AP5 (Cat. No. 0105) and displays approximately 52-fold higher potency than the L-isomer, L-AP5 (Cat. No. 0107). In vitro D-AP5 reduces NMDA-induced depolarization of cortical neurons, with no effect on the response to L-Quisqualic acid (Cat. No. 0188) or Kainic acid (Cat. No. 0222). Following spinal injection, D-AP5 results in rapid reduction of NMDA-response but no effect on spontaneously active neurons. . DL Mixture, L-isomer and sodium salt also available.
top caption :
Potent and selective NMDA receptor antagonist; more active form of DL-AP5
extended description :
Potent and selective NMDA receptor antagonist; more active form of DL-AP5
chemical name text :
D-(-)-2-Amino-5-phosphonopentanoic acid
formula :
C5H12NO5P
formula text :
C5H12NO5P
cas num :
79055-68-8
USD :
103 USD
product details :
Potent and selective NMDA receptor antagonist; more active form of DL-AP5
alt names :
2-APV, D -APV, D -2-amino-5-phosphonovalerate
storage :
Store at RT
more info or order :
company information
Tocris Bioscience
The Watkins Building
Atlantic Road
Avonmouth, Bristol
BS11 9QD
info@bio-techne.com
https://www.tocris.com
800-343-7475
headquarters: UK