product summary
company name :
Takara Bio Clontech
other brands :
TaKaRa
product type :
antibody
product name :
Living Colors® A.v. Monoclonal Antibody (JL-8)
catalog :
632381
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
JL-8
reactivity :
, African green monkey, human, mouse, rat, fruit fly, thale cress, rabbit
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 76
Published Application/Species/Sample/DilutionReference
  • western blot; African green monkey; loading ...; fig 6e
Mauriac S, Hien Y, Bird J, Carvalho S, Peyroutou R, Lee S, et al. Defective Gpsm2/Gαi3 signalling disrupts stereocilia development and growth cone actin dynamics in Chudley-McCullough syndrome. Nat Commun. 2017;8:14907 pubmed publisher
  • western blot; mouse; loading ...; fig 4c
Zhao T, Hong Y, Yin P, Li S, Li X. Differential HspBP1 expression accounts for the greater vulnerability of neurons than astrocytes to misfolded proteins. Proc Natl Acad Sci U S A. 2017;114:E7803-E7811 pubmed publisher
  • western blot; human; fig s10
Stupfler B, Birck C, Seraphin B, Mauxion F. BTG2 bridges PABPC1 RNA-binding domains and CAF1 deadenylase to control cell proliferation. Nat Commun. 2016;7:10811 pubmed publisher
  • western blot; mouse; fig 6
Aizawa S, Okamoto T, Sugiyama Y, Kouwaki T, Ito A, Suzuki T, et al. TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis. Nat Commun. 2016;7:11379 pubmed publisher
  • western blot; mouse; fig 3a
Murthy M, Kurz T, O'shaughnessy K. ROMK expression remains unaltered in a mouse model of familial hyperkalemic hypertension caused by the CUL3Δ403-459 mutation. Physiol Rep. 2016;4: pubmed publisher
  • western blot; human; 1:2000; fig 7
Kraft L, Manral P, Dowler J, Kenworthy A. Nuclear LC3 Associates with Slowly Diffusing Complexes that Survey the Nucleolus. Traffic. 2016;17:369-99 pubmed publisher
  • immunohistochemistry; mouse; 1:250; fig s8
Baligar P, Mukherjee S, Kochat V, Rastogi A, Mukhopadhyay A. Molecular and Cellular Functions Distinguish Superior Therapeutic Efficiency of Bone Marrow CD45 Cells Over Mesenchymal Stem Cells in Liver Cirrhosis. Stem Cells. 2016;34:135-47 pubmed publisher
  • western blot; thale cress; fig 1
Binkert M, Crocco C, Ekundayo B, Lau K, Raffelberg S, Tilbrook K, et al. Revisiting chromatin binding of the Arabidopsis UV-B photoreceptor UVR8. BMC Plant Biol. 2016;16:42 pubmed publisher
  • western blot; fruit fly; 1:5000; loading ...; fig 5c
Galletta B, Fagerstrom C, Schoborg T, McLamarrah T, Ryniawec J, Buster D, et al. A centrosome interactome provides insight into organelle assembly and reveals a non-duplication role for Plk4. Nat Commun. 2016;7:12476 pubmed publisher
  • western blot; human; 1:2000; fig s2
Soo Lee N, Jin Chung H, Kim H, Yun Lee S, Ji J, Seo Y, et al. TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage. Nat Commun. 2016;7:10463 pubmed publisher
  • immunohistochemistry; thale cress; 1:1500; fig 2
Zhang H, Cui F, Wu Y, Lou L, Liu L, Tian M, et al. The RING finger ubiquitin E3 ligase SDIR1 targets SDIR1-INTERACTING PROTEIN1 for degradation to modulate the salt stress response and ABA signaling in Arabidopsis. Plant Cell. 2015;27:214-27 pubmed publisher
  • western blot; thale cress; 1:1000; fig 1
Kim D, Lee J, Xu Z, Geem K, Kwon Y, Park J, et al. Cytosolic targeting factor AKR2A captures chloroplast outer membrane-localized client proteins at the ribosome during translation. Nat Commun. 2015;6:6843 pubmed publisher
  • western blot; human; fig 7a
Yang C, Chiang C, Chen C, Lee Y, Wu M, Tsou Y, et al. Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58). J Biomed Sci. 2015;22:33 pubmed publisher
  • immunocytochemistry; human; fig 2
Chou W, Hu L, Hsiung C, Shen C. Initiation of the ATM-Chk2 DNA damage response through the base excision repair pathway. Carcinogenesis. 2015;36:832-40 pubmed publisher
  • western blot; human; 1:4000
Klein W, Westendorf C, Schmidt A, Conill-Cortés M, Rutz C, Blohs M, et al. Defining a conformational consensus motif in cotransin-sensitive signal sequences: a proteomic and site-directed mutagenesis study. PLoS ONE. 2015;10:e0120886 pubmed publisher
  • western blot; human; fig 1
Bund T, Spoden G, Koynov K, Hellmann N, Boukhallouk F, Arnold P, et al. An L2 SUMO interacting motif is important for PML localization and infection of human papillomavirus type 16. Cell Microbiol. 2014;16:1179-200 pubmed publisher
  • immunocytochemistry; human; 1:100; loading ...; fig 2a
  • western blot; human; loading ...; fig 2b
Lee M, Venkitaraman A. A cancer-associated mutation inactivates a region of the high-mobility group protein HMG20b essential for cytokinesis. Cell Cycle. 2014;13:2554-63 pubmed publisher
  • immunocytochemistry; rat
Li L, Ginet V, Liu X, Vergun O, Tuittila M, Mathieu M, et al. The nNOS-p38MAPK pathway is mediated by NOS1AP during neuronal death. J Neurosci. 2013;33:8185-201 pubmed publisher
  • immunocytochemistry; human
Gu B, Eick D, Bensaude O. CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo. Nucleic Acids Res. 2013;41:1591-603 pubmed publisher
  • immunoprecipitation; human
  • western blot; human; 1:1000
Tanaka T, Iino M. Sec6 regulated cytoplasmic translocation and degradation of p27 via interactions with Jab1 and Siah1. Cell Signal. 2014;26:2071-85 pubmed publisher
  • western blot; human; fig 1
Zou J, Zhang D, Qin G, Chen X, Wang H, Zhang D. BRCA1 and FancJ cooperatively promote interstrand crosslinker induced centrosome amplification through the activation of polo-like kinase 1. Cell Cycle. 2014;13:3685-97 pubmed publisher
  • immunohistochemistry; rabbit; 1:100
Pan F, Keung J, Kim I, Snuggs M, Mills S, O'BRIEN J, et al. Connexin 57 is expressed by the axon terminal network of B-type horizontal cells in the rabbit retina. J Comp Neurol. 2012;520:2256-74 pubmed publisher
  • western blot; human
Khalouei S, Chow A, Brown I. Localization of heat shock protein HSPA6 (HSP70B') to sites of transcription in cultured differentiated human neuronal cells following thermal stress. J Neurochem. 2014;131:743-54 pubmed publisher
  • western blot; human
O'Rourke J, Gareau J, Ochaba J, Song W, Rasko T, Reverter D, et al. SUMO-2 and PIAS1 modulate insoluble mutant huntingtin protein accumulation. Cell Rep. 2013;4:362-75 pubmed publisher
  • immunocytochemistry; human
Katoh H, Okamoto T, Fukuhara T, Kambara H, Morita E, Mori Y, et al. Japanese encephalitis virus core protein inhibits stress granule formation through an interaction with Caprin-1 and facilitates viral propagation. J Virol. 2013;87:489-502 pubmed publisher
  • western blot; human
Kuo P, Huang Y, Hsieh C, Lee J, Lin B, Hung L. STK31 is a cell-cycle regulated protein that contributes to the tumorigenicity of epithelial cancer cells. PLoS ONE. 2014;9:e93303 pubmed publisher
Guimarães-Camboa N, Cattaneo P, Sun Y, Moore-Morris T, Gu Y, Dalton N, et al. Pericytes of Multiple Organs Do Not Behave as Mesenchymal Stem Cells In Vivo. Cell Stem Cell. 2017;: pubmed publisher
Arthur L, Chung J, Jankirama P, Keefer K, Kolotilin I, Pavlovic-Djuranovic S, et al. Rapid generation of hypomorphic mutations. Nat Commun. 2017;8:14112 pubmed publisher
Dick M, Sborgi L, Rühl S, Hiller S, Broz P. ASC filament formation serves as a signal amplification mechanism for inflammasomes. Nat Commun. 2016;7:11929 pubmed publisher
Li Q, Zhu Y, Hou L, Wang J, Hu G, Fang X, et al. C23 promotes tumorigenesis via suppressing p53 activity. Oncotarget. 2016;7:58274-58285 pubmed publisher
Bindesbøll C, Tan S, Bott D, Cho T, Tamblyn L, MacPherson L, et al. TCDD-inducible poly-ADP-ribose polymerase (TIPARP/PARP7) mono-ADP-ribosylates and co-activates liver X receptors. Biochem J. 2016;473:899-910 pubmed publisher
Ni C, Seth D, Fonseca F, Wang L, Xiao T, Gruber P, et al. Polyglutamine Tract Expansion Increases S-Nitrosylation of Huntingtin and Ataxin-1. PLoS ONE. 2016;11:e0163359 pubmed publisher
Thomas G, Bandopadhyay K, Sutradhar S, Renjith M, Singh P, Gireesh K, et al. EB1 regulates attachment of Ska1 with microtubules by forming extended structures on the microtubule lattice. Nat Commun. 2016;7:11665 pubmed publisher
Tandon P, Wilczewski C, Williams C, Conlon F. The Lhx9-integrin pathway is essential for positioning of the proepicardial organ. Development. 2016;143:831-40 pubmed publisher
Mosadeghi R, Reichermeier K, Winkler M, Schreiber A, Reitsma J, Zhang Y, et al. Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle. elife. 2016;5: pubmed publisher
Guo X, Wang X, Wang Z, Banerjee S, Yang J, Huang L, et al. Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis. Nat Cell Biol. 2016;18:202-12 pubmed publisher
Gigante E, Benaliouad F, Zamora-Olivencia V, Wise R. Optogenetic Activation of a Lateral Hypothalamic-Ventral Tegmental Drive-Reward Pathway. PLoS ONE. 2016;11:e0158885 pubmed publisher
McLaughlin D, Coey C, Yang W, Drohat A, Matunis M. Characterizing Requirements for Small Ubiquitin-like Modifier (SUMO) Modification and Binding on Base Excision Repair Activity of Thymine-DNA Glycosylase in Vivo. J Biol Chem. 2016;291:9014-24 pubmed publisher
Jimenez L, Wang J, Morrison M, Whatcott C, Soh K, Warner S, et al. Phenotypic chemical screening using a zebrafish neural crest EMT reporter identifies retinoic acid as an inhibitor of epithelial morphogenesis. Dis Model Mech. 2016;9:389-400 pubmed publisher
Paulissen S, Slubowski C, Roesner J, Huang L. Timely Closure of the Prospore Membrane Requires SPS1 and SPO77 in Saccharomyces cerevisiae. Genetics. 2016;203:1203-16 pubmed publisher
Ahn J, Kim S, Na W, Baek S, Kim J, Min K, et al. SERBP1 affects homologous recombination-mediated DNA repair by regulation of CtIP translation during S phase. Nucleic Acids Res. 2015;43:6321-33 pubmed publisher
Cary G, Vinh D, May P, Kuestner R, DUDLEY A. Proteomic Analysis of Dhh1 Complexes Reveals a Role for Hsp40 Chaperone Ydj1 in Yeast P-Body Assembly. G3 (Bethesda). 2015;5:2497-511 pubmed publisher
Han B, Tiwari A, Kenworthy A. Tagging strategies strongly affect the fate of overexpressed caveolin-1. Traffic. 2015;16:417-38 pubmed publisher
Breznau E, Semack A, Higashi T, Miller A. MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell-cell junctions in epithelial cells. Mol Biol Cell. 2015;26:2439-55 pubmed publisher
Love C, Prince V. Rest represses maturation within migrating facial branchiomotor neurons. Dev Biol. 2015;401:220-35 pubmed publisher
Parchem R, Moore N, Fish J, Parchem J, Braga T, Shenoy A, et al. miR-302 Is Required for Timing of Neural Differentiation, Neural Tube Closure, and Embryonic Viability. Cell Rep. 2015;12:760-73 pubmed publisher
Yamagishi S, Yamada K, Sawada M, Nakano S, Mori N, Sawamoto K, et al. Netrin-5 is highly expressed in neurogenic regions of the adult brain. Front Cell Neurosci. 2015;9:146 pubmed publisher
Kaiser S, Mao K, Taherbhoy A, Yu S, Olszewski J, Duda D, et al. Noncanonical E2 recruitment by the autophagy E1 revealed by Atg7-Atg3 and Atg7-Atg10 structures. Nat Struct Mol Biol. 2012;19:1242-9 pubmed publisher
Chen C, Ha B, Thévenin A, Lou H, Zhang R, Yip K, et al. Identification of a major determinant for serine-threonine kinase phosphoacceptor specificity. Mol Cell. 2014;53:140-7 pubmed publisher
Schuiki I, Zhang L, Volchuk A. Endoplasmic reticulum redox state is not perturbed by pharmacological or pathological endoplasmic reticulum stress in live pancreatic β-cells. PLoS ONE. 2012;7:e48626 pubmed publisher
Cortez V, MANN M, Tekmal S, Suzuki T, Miyata N, Rodriguez-Aguayo C, et al. Targeting the PELP1-KDM1 axis as a potential therapeutic strategy for breast cancer. Breast Cancer Res. 2012;14:R108 pubmed publisher
Chen J, Repunte-Canonigo V, Kawamura T, Lefebvre C, Shin W, Howell L, et al. Hypothalamic proteoglycan syndecan-3 is a novel cocaine addiction resilience factor. Nat Commun. 2013;4:1955 pubmed publisher
Khalouei S, Chow A, Brown I. Stress-induced localization of HSPA6 (HSP70B') and HSPA1A (HSP70-1) proteins to centrioles in human neuronal cells. Cell Stress Chaperones. 2014;19:321-7 pubmed publisher
Fang X, Lu Q, Emoto K, Adler P. The Drosophila Fry protein interacts with Trc and is highly mobile in vivo. BMC Dev Biol. 2010;10:40 pubmed publisher
Bogani D, Morgan M, Nelson A, Costello I, McGouran J, Kessler B, et al. The PR/SET domain zinc finger protein Prdm4 regulates gene expression in embryonic stem cells but plays a nonessential role in the developing mouse embryo. Mol Cell Biol. 2013;33:3936-50 pubmed publisher
Jiang L, Teng G, Chan E, Au S, Wise H, Lee S, et al. Impact of cell type and epitope tagging on heterologous expression of G protein-coupled receptor: a systematic study on angiotensin type II receptor. PLoS ONE. 2012;7:e47016 pubmed publisher
Chiang Y, Ho K, Sun C, Chiu J, Lee F, Liao F, et al. CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration. PLoS ONE. 2013;8:e61761 pubmed publisher
Barras D, Lorusso G, Lhermitte B, Viertl D, Ruegg C, Widmann C. Fragment N2, a caspase-3-generated RasGAP fragment, inhibits breast cancer metastatic progression. Int J Cancer. 2014;135:242-7 pubmed publisher
Schulman V, Folker E, Rosen J, Baylies M. Syd/JIP3 and JNK signaling are required for myonuclear positioning and muscle function. PLoS Genet. 2014;10:e1004880 pubmed publisher
Hartley T, Siva M, Lai E, Teodoro T, Zhang L, Volchuk A. Endoplasmic reticulum stress response in an INS-1 pancreatic beta-cell line with inducible expression of a folding-deficient proinsulin. BMC Cell Biol. 2010;11:59 pubmed publisher
Grau C, Arato K, Fernández-Fernández J, Valderrama A, Sindreu C, Fillat C, et al. DYRK1A-mediated phosphorylation of GluN2A at Ser(1048) regulates the surface expression and channel activity of GluN1/GluN2A receptors. Front Cell Neurosci. 2014;8:331 pubmed publisher
Talaty P, Emery A, Everly D. Characterization of the latent membrane protein 1 signaling complex of Epstein-Barr virus in the membrane of mammalian cells with bimolecular fluorescence complementation. Virol J. 2011;8:414 pubmed publisher
Du W, Jiang P, Mancuso A, Stonestrom A, Brewer M, Minn A, et al. TAp73 enhances the pentose phosphate pathway and supports cell proliferation. Nat Cell Biol. 2013;15:991-1000 pubmed publisher
Seredick S, Hutchinson S, Van Ryswyk L, Talbot J, Eisen J. Lhx3 and Lhx4 suppress Kolmer-Agduhr interneuron characteristics within zebrafish axial motoneurons. Development. 2014;141:3900-9 pubmed publisher
Hur J, Zinchenko M, Djuranovic S, Green R. Regulation of Argonaute slicer activity by guide RNA 3' end interactions with the N-terminal lobe. J Biol Chem. 2013;288:7829-40 pubmed publisher
Kabgani N, Grigoleit T, Schulte K, Sechi A, Sauer-Lehnen S, Tag C, et al. Primary cultures of glomerular parietal epithelial cells or podocytes with proven origin. PLoS ONE. 2012;7:e34907 pubmed publisher
Zhang L, Nosak C, Sollazzo P, Odisho T, Volchuk A. IRE1 inhibition perturbs the unfolded protein response in a pancreatic β-cell line expressing mutant proinsulin, but does not sensitize the cells to apoptosis. BMC Cell Biol. 2014;15:29 pubmed publisher
Subramanian A, Schilling T. Thrombospondin-4 controls matrix assembly during development and repair of myotendinous junctions. elife. 2014;3: pubmed publisher
Xiao B, Sanders M, Carmena D, Bright N, Haire L, Underwood E, et al. Structural basis of AMPK regulation by small molecule activators. Nat Commun. 2013;4:3017 pubmed publisher
Varma D, Chandrasekaran S, Sundin L, Reidy K, Wan X, Chasse D, et al. Recruitment of the human Cdt1 replication licensing protein by the loop domain of Hec1 is required for stable kinetochore-microtubule attachment. Nat Cell Biol. 2012;14:593-603 pubmed publisher
Miller A, Bement W. Regulation of cytokinesis by Rho GTPase flux. Nat Cell Biol. 2009;11:71-7 pubmed publisher
Meehan A, Saenz D, Guevera R, Morrison J, Peretz M, Fadel H, et al. A cyclophilin homology domain-independent role for Nup358 in HIV-1 infection. PLoS Pathog. 2014;10:e1003969 pubmed publisher
Jeyasekharan A, Liu Y, Hattori H, Pisupati V, Jonsdottir A, Rajendra E, et al. A cancer-associated BRCA2 mutation reveals masked nuclear export signals controlling localization. Nat Struct Mol Biol. 2013;20:1191-8 pubmed publisher
Fan X, Jin W, Lu J, Wang J, Wang Y. Rapid and reversible knockdown of endogenous proteins by peptide-directed lysosomal degradation. Nat Neurosci. 2014;17:471-80 pubmed publisher
Ye Y, Lee I, Runge K, Wu J. Roles of putative Rho-GEF Gef2 in division-site positioning and contractile-ring function in fission yeast cytokinesis. Mol Biol Cell. 2012;23:1181-95 pubmed publisher
Laporte D, Coffman V, Lee I, Wu J. Assembly and architecture of precursor nodes during fission yeast cytokinesis. J Cell Biol. 2011;192:1005-21 pubmed publisher
company information
Takara Bio Clontech
www.clontech.com
headquarters: US