Published Application/Species/Sample/Dilution | Reference |
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- western blot knockout validation; mouse; 1:500; fig 4
- immunohistochemistry; mouse; 1:100; fig 5
| Sato S, Kawamata Y, Takahashi A, Imai Y, Hanyu A, Okuma A, et al. Ablation of the p16(INK4a) tumour suppressor reverses ageing phenotypes of klotho mice. Nat Commun. 2015;6:7035 pubmed publisher
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- western blot knockout validation; mouse; fig 1
- immunohistochemistry - paraffin section; mouse
- immunocytochemistry; mouse
| Lindberg K, Amin R, Moe O, Hu M, Erben R, Östman Wernerson A, et al. The kidney is the principal organ mediating klotho effects. J Am Soc Nephrol. 2014;25:2169-75 pubmed publisher
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- western blot; rat; 1:1000; loading ...; fig 4f
| Yamamoto K, Sato K, Yukita M, Yasuda M, Omodaka K, Ryu M, et al. The neuroprotective effect of latanoprost acts via klotho-mediated suppression of calpain activation after optic nerve transection. J Neurochem. 2017;140:495-508 pubmed publisher
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| Fernández A, Sebti S, Wei Y, Zou Z, Shi M, McMillan K, et al. Disruption of the beclin 1-BCL2 autophagy regulatory complex promotes longevity in mice. Nature. 2018;558:136-140 pubmed publisher
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| Takeshita A, Kawakami K, Furushima K, Miyajima M, Sakaguchi K. Central role of the proximal tubular ?Klotho/FGF receptor complex in FGF23-regulated phosphate and vitamin D metabolism. Sci Rep. 2018;8:6917 pubmed publisher
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| Bon N, Frangi G, Sourice S, Guicheux J, Beck Cormier S, Beck L. Phosphate-dependent FGF23 secretion is modulated by PiT2/Slc20a2. Mol Metab. 2018;11:197-204 pubmed publisher
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| Dalton G, An S, Al Juboori S, Nischan N, Yoon J, Dobrinskikh E, et al. Soluble klotho binds monosialoganglioside to regulate membrane microdomains and growth factor signaling. Proc Natl Acad Sci U S A. 2017;114:752-757 pubmed publisher
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