product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
IBA1
catalog :
234 003
quantity :
50 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 36
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:500; loading ...; fig 1b
Steubler V, Erdinger S, Back M, Ludewig S, Fässler D, Richter M, et al. Loss of all three APP family members during development impairs synaptic function and plasticity, disrupts learning, and causes an autism-like phenotype. EMBO J. 2021;40:e107471 pubmed publisher
  • western blot; mouse; loading ...; fig s3e
Gruber T, Pan C, Contreras R, Wiedemann T, Morgan D, Skowronski A, et al. Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension. Cell Metab. 2021;33:1155-1170.e10 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 5b
Düsedau H, Kleveman J, Figueiredo C, Biswas A, Steffen J, Kliche S, et al. p75NTR regulates brain mononuclear cell function and neuronal structure in Toxoplasma infection-induced neuroinflammation. Glia. 2019;67:193-211 pubmed publisher
Pitman K, Ricci R, Gasperini R, Beasley S, Pavez M, Charlesworth J, et al. The voltage-gated calcium channel CaV1.2 promotes adult oligodendrocyte progenitor cell survival in the mouse corpus callosum but not motor cortex. Glia. 2020;68:376-392 pubmed publisher
Pyka Fosciak G, Zemła J, Lis G, Litwin J, Lekka M. Changes in spinal cord stiffness in the course of experimental autoimmune encephalomyelitis, a mouse model of multiple sclerosis. Arch Biochem Biophys. 2019;:108221 pubmed publisher
Grotegut P, Kuehn S, Meißner W, Dick H, Joachim S. Intravitreal S100B Injection Triggers a Time-Dependent Microglia Response in a Pro-Inflammatory Manner in Retina and Optic Nerve. Mol Neurobiol. 2019;: pubmed publisher
Urban I, Kerimoglu C, Sakib M, Wang H, Benito E, Thaller C, et al. TIP60/KAT5 is required for neuronal viability in hippocampal CA1. Sci Rep. 2019;9:16173 pubmed publisher
Namba T, Shinohara H, Seki T. Non-radial tortuous migration with cell polarity alterations of newly generated granule neurons in the neonatal rat dentate gyrus. Brain Struct Funct. 2019;224:3247-3262 pubmed publisher
Kyrargyri V, Madry C, Rifat A, Arancibia Carcamo I, Jones S, Chan V, et al. P2Y13 receptors regulate microglial morphology, surveillance, and resting levels of interleukin 1β release. Glia. 2019;: pubmed publisher
Leiter I, Bascuñana P, BENGEL F, Bankstahl J, Bankstahl M. Attenuation of epileptogenesis by 2-deoxy-d-glucose is accompanied by increased cerebral glucose supply, microglial activation and reduced astrocytosis. Neurobiol Dis. 2019;:104510 pubmed publisher
Balser C, Wolf A, Herb M, Langmann T. Co-inhibition of PGF and VEGF blocks their expression in mononuclear phagocytes and limits neovascularization and leakage in the murine retina. J Neuroinflammation. 2019;16:26 pubmed publisher
Hernando S, Requejo C, Herran E, Ruiz Ortega J, Morera Herreras T, Lafuente J, et al. Beneficial effects of n-3 polyunsaturated fatty acids administration in a partial lesion model of Parkinson's disease: The role of glia and NRf2 regulation. Neurobiol Dis. 2019;121:252-262 pubmed publisher
Quiñones M, Al Massadi O, Folgueira C, Bremser S, Gallego R, Torres Leal L, et al. p53 in AgRP neurons is required for protection against diet-induced obesity via JNK1. Nat Commun. 2018;9:3432 pubmed publisher
Ranson M, Del Bigio M. Chronic near lifetime toluene exposure in rodents does not replicate solvent abuse leukoencephalopathy in humans. Neurotoxicology. 2018;69:260-265 pubmed publisher
Bankstahl M, Breuer H, Leiter I, Märkel M, Bascuñana P, Michalski D, et al. Blood-Brain Barrier Leakage during Early Epileptogenesis Is Associated with Rapid Remodeling of the Neurovascular Unit. Eneuro. 2018;5: pubmed publisher
Evanson N, Guilhaume Correa F, Herman J, Goodman M. Optic tract injury after closed head traumatic brain injury in mice: A model of indirect traumatic optic neuropathy. PLoS ONE. 2018;13:e0197346 pubmed publisher
Kuehn S, Reinehr S, Stute G, Rodust C, Grotegut P, Hensel A, et al. Interaction of complement system and microglia activation in retina and optic nerve in a NMDA damage model. Mol Cell Neurosci. 2018;89:95-106 pubmed publisher
Richter M, Ludewig S, Winschel A, Abel T, Bold C, Salzburger L, et al. Distinct in vivo roles of secreted APP ectodomain variants APPsα and APPsβ in regulation of spine density, synaptic plasticity, and cognition. EMBO J. 2018;37: pubmed publisher
Di Curzio D, Nagra G, Mao X, Del Bigio M. Memantine treatment of juvenile rats with kaolin-induced hydrocephalus. Brain Res. 2018;1689:54-62 pubmed publisher
Rincon M, de Vin F, Duque S, Fripont S, Castaldo S, Bouhuijzen Wenger J, et al. Widespread transduction of astrocytes and neurons in the mouse central nervous system after systemic delivery of a self-complementary AAV-PHP.B vector. Gene Ther. 2018;25:83-92 pubmed publisher
Hosseini S, Wilk E, Michaelsen Preusse K, Gerhauser I, Baumgartner W, Geffers R, et al. Long-Term Neuroinflammation Induced by Influenza A Virus Infection and the Impact on Hippocampal Neuron Morphology and Function. J Neurosci. 2018;38:3060-3080 pubmed publisher
Salas I, Weerasekera A, Ahmed T, Callaerts Vegh Z, Himmelreich U, D Hooge R, et al. High fat diet treatment impairs hippocampal long-term potentiation without alterations of the core neuropathological features of Alzheimer disease. Neurobiol Dis. 2018;113:82-96 pubmed publisher
Pfuhlmann K, Schriever S, Legutko B, Baumann P, Harrison L, Kabra D, et al. Calcineurin A beta deficiency ameliorates HFD-induced hypothalamic astrocytosis in mice. J Neuroinflammation. 2018;15:35 pubmed publisher
Madry C, Arancibia Carcamo I, Kyrargyri V, Chan V, Hamilton N, Attwell D. Effects of the ecto-ATPase apyrase on microglial ramification and surveillance reflect cell depolarization, not ATP depletion. Proc Natl Acad Sci U S A. 2018;115:E1608-E1617 pubmed publisher
Madry C, Kyrargyri V, Arancibia Carcamo I, Jolivet R, Kohsaka S, Bryan R, et al. Microglial Ramification, Surveillance, and Interleukin-1? Release Are Regulated by the Two-Pore Domain K+ Channel THIK-1. Neuron. 2018;97:299-312.e6 pubmed publisher
Hosford B, Rowley S, Liska J, Danzer S. Ablation of peri-insult generated granule cells after epilepsy onset halts disease progression. Sci Rep. 2017;7:18015 pubmed publisher
Gao Y, Vidal Itriago A, Milanova I, Korpel N, Kalsbeek M, Tom R, et al. Deficiency of leptin receptor in myeloid cells disrupts hypothalamic metabolic circuits and causes body weight increase. Mol Metab. 2018;7:155-160 pubmed publisher
Quarta C, Clemmensen C, Zhu Z, Yang B, Joseph S, Lutter D, et al. Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity. Cell Metab. 2017;26:620-632.e6 pubmed publisher
Gao Y, Bielohuby M, Fleming T, Grabner G, Foppen E, Bernhard W, et al. Dietary sugars, not lipids, drive hypothalamic inflammation. Mol Metab. 2017;6:897-908 pubmed publisher
Michalski D, Hofmann S, Pitsch R, Grosche J, Hartig W. Neurovascular Specifications in the Alzheimer-Like Brain of Mice Affected by Focal Cerebral Ischemia: Implications for Future Therapies. J Alzheimers Dis. 2017;59:655-674 pubmed publisher
Yi C, Walter M, Gao Y, Pitra S, Legutko B, Kälin S, et al. TNFα drives mitochondrial stress in POMC neurons in obesity. Nat Commun. 2017;8:15143 pubmed publisher
Michalski D, Pitsch R, Pillai D, Mages B, Aleithe S, Grosche J, et al. Delayed histochemical alterations within the neurovascular unit due to transient focal cerebral ischemia and experimental treatment with neurotrophic factors. PLoS ONE. 2017;12:e0174996 pubmed publisher
Batiuk M, de Vin F, Duque S, Li C, Saito T, Saido T, et al. An immunoaffinity-based method for isolating ultrapure adult astrocytes based on ATP1B2 targeting by the ACSA-2 antibody. J Biol Chem. 2017;292:8874-8891 pubmed publisher
Hosford B, Liska J, Danzer S. Ablation of Newly Generated Hippocampal Granule Cells Has Disease-Modifying Effects in Epilepsy. J Neurosci. 2016;36:11013-11023 pubmed
Hester M, Hosford B, Santos V, Singh S, Rolle I, LaSarge C, et al. Impact of rapamycin on status epilepticus induced hippocampal pathology and weight gain. Exp Neurol. 2016;280:1-12 pubmed publisher
Kurhade C, Zegenhagen L, Weber E, Nair S, Michaelsen Preusse K, Spanier J, et al. Type I Interferon response in olfactory bulb, the site of tick-borne flavivirus accumulation, is primarily regulated by IPS-1. J Neuroinflammation. 2016;13:22 pubmed publisher
product information
Cat. Nr. :
234 003
Antigen :
IBA1
Synonyms :
AIF 1, microglia, IBA 1, AIF1, Aif 1
Host Species :
rabbit
Tpye :
polyclonal
Form :
affinity purified 1
Immunogen :
Synthetic peptide corresponding to AA 134 to 147 from rat IBA1 (UniProt Id: P55009)
Reactivity :
human, rat, mouse
WB :
WB
IP :
IP
ICC :
ICC
IHC :
IHC
IHC P :
IHC-P
Quantity :
50 µg
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany