product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
GABA-A receptor alpha2
catalog :
224 103
quantity :
50 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
/
reactivity :
human, mouse, rat
application :
immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 9
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; rat; 1:1000; loading ...; fig 1e
Lorenzo L, Godin A, Ferrini F, Bachand K, Plasencia Fernandez I, Labrecque S, et al. Enhancing neuronal chloride extrusion rescues α2/α3 GABAA-mediated analgesia in neuropathic pain. Nat Commun. 2020;11:869 pubmed publisher
  • immunohistochemistry; rat; 1:1000; fig 11
Kerti Szigeti K, Nusser Z. Similar GABAA receptor subunit composition in somatic and axon initial segment synapses of hippocampal pyramidal cells. elife. 2016;5: pubmed publisher
  • immunohistochemistry - paraffin section; mouse; fig 8
Folmsbee S, Wilcox D, Tyberghein K, De Bleser P, Tourtellotte W, van Hengel J, et al. ?T-catenin in restricted brain cell types and its potential connection to autism. J Mol Psychiatry. 2016;4:2 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:500; fig 3
Gao Y, Heldt S. Enrichment of GABAA Receptor α-Subunits on the Axonal Initial Segment Shows Regional Differences. Front Cell Neurosci. 2016;10:39 pubmed publisher
Nathanson A, Zhang Y, Smalley J, Ollerhead T, Rodriguez Santos M, Andrews P, et al. Identification of a Core Amino Acid Motif within the α Subunit of GABAARs that Promotes Inhibitory Synaptogenesis and Resilience to Seizures. Cell Rep. 2019;28:670-681.e8 pubmed publisher
Mukherjee J, Cardarelli R, Cantaut Belarif Y, Deeb T, Srivastava D, Tyagarajan S, et al. Estradiol modulates the efficacy of synaptic inhibition by decreasing the dwell time of GABAA receptors at inhibitory synapses. Proc Natl Acad Sci U S A. 2017;114:11763-11768 pubmed publisher
Smith K, Jones K, Kopeikina K, Burette A, Copits B, Yoon S, et al. Cadherin-10 Maintains Excitatory/Inhibitory Ratio through Interactions with Synaptic Proteins. J Neurosci. 2017;37:11127-11139 pubmed publisher
Chang J, Chen F, Yoon Y, Jung E, Babcock H, Kang J, et al. Iterative expansion microscopy. Nat Methods. 2017;14:593-599 pubmed publisher
Saito A, Taniguchi Y, Rannals M, Merfeld E, Ballinger M, Koga M, et al. Early postnatal GABAA receptor modulation reverses deficits in neuronal maturation in a conditional neurodevelopmental mouse model of DISC1. Mol Psychiatry. 2016;21:1449-59 pubmed publisher
product information
Cat. Nr. :
224 103
Antigen :
GABA-A receptor alpha2
Host Species :
rabbit
Tpye :
polyclonal
Form :
affinity purified
Immunogen :
Synthetic peptide corresponding to AA 29 to 37 from rat GABA-A receptor alpha2 (UniProt Id: P23576)
Reactivity :
human, rat, mouse
IP :
IP
ICC :
ICC
IHC :
IHC
EM :
EM
KO :
yes
Quantity :
50 µg
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany