product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
m6A
catalog :
202 003
quantity :
50 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
/
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, dot blot, other
more info or order :
citations: 110
Published Application/Species/Sample/DilutionReference
  • other; mouse; loading ...; fig 1a
Liu Y, You Y, Lu Z, Yang J, Li P, Liu L, et al. N6-methyladenosine RNA modification-mediated cellular metabolism rewiring inhibits viral replication. Science. 2019;365:1171-1176 pubmed publisher
  • western blot; human; fig 5b
Su R, Dong L, Li C, Nachtergaele S, Wunderlich M, Qing Y, et al. R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling. Cell. 2018;172:90-105.e23 pubmed publisher
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 2c
Yu J, Chen M, Huang H, Zhu J, Song H, Zhu J, et al. Dynamic m6A modification regulates local translation of mRNA in axons. Nucleic Acids Res. 2018;46:1412-1423 pubmed publisher
  • immunocytochemistry; human; loading ...; fig s2j
  • western blot; human; loading ...; fig s2c
Xiang Y, Laurent B, Hsu C, Nachtergaele S, Lu Z, Sheng W, et al. RNA m6A methylation regulates the ultraviolet-induced DNA damage response. Nature. 2017;543:573-576 pubmed publisher
Su H, Wang G, Wu L, Ma X, Ying K, Zhang R. Transcriptome-wide map of m6A circRNAs identified in a rat model of hypoxia mediated pulmonary hypertension. BMC Genomics. 2020;21:39 pubmed publisher
Zou D, Dong L, Li C, Yin Z, Rao S, Zhou Q. The m6A eraser FTO facilitates proliferation and migration of human cervical cancer cells. Cancer Cell Int. 2019;19:321 pubmed publisher
Koh C, Goh Y, Goh W. Atlas of quantitative single-base-resolution N6-methyl-adenine methylomes. Nat Commun. 2019;10:5636 pubmed publisher
Kotsarenko K, Věchtová P, Hammerová Z, Langova N, Malinovská L, Wimmerova M, et al. Newly identified DNA methyltransferases of Ixodes ricinus ticks. Ticks Tick Borne Dis. 2019;:101348 pubmed publisher
Hsu P, Shi H, Zhu A, Lu Z, Miller N, Edens B, et al. The RNA-binding protein FMRP facilitates the nuclear export of N6-methyladenosine-containing mRNAs. J Biol Chem. 2019;: pubmed publisher
Jia R, Chai P, Wang S, Sun B, Xu Y, Yang Y, et al. m6A modification suppresses ocular melanoma through modulating HINT2 mRNA translation. Mol Cancer. 2019;18:161 pubmed publisher
Wang Y, Sheng Y, Liu Y, Zhang W, Cheng T, Duan L, et al. A distinct class of eukaryotic MT-A70 methyltransferases maintain symmetric DNA N6-adenine methylation at the ApT dinucleotides as an epigenetic mark associated with transcription. Nucleic Acids Res. 2019;47:11771-11789 pubmed publisher
Shi Y, Fan S, Wu M, Zuo Z, Li X, Jiang L, et al. YTHDF1 links hypoxia adaptation and non-small cell lung cancer progression. Nat Commun. 2019;10:4892 pubmed publisher
Yu J, Shen L, Liu Y, Ming H, Zhu X, Chu M, et al. The m6A methyltransferase METTL3 cooperates with demethylase ALKBH5 to regulate osteogenic differentiation through NF-κB signaling. Mol Cell Biochem. 2019;: pubmed publisher
Wang Y, Wang R, Yao B, Hu T, Li Z, Liu Y, et al. TNF-α suppresses sweat gland differentiation of MSCs by reducing FTO-mediated m6A-demethylation of Nanog mRNA. Sci China Life Sci. 2019;: pubmed publisher
Chen R, Chen X, Xia L, Zhang J, Pan Z, Ma X, et al. N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis. Nat Commun. 2019;10:4695 pubmed publisher
Matsuzawa S, Wakata Y, Ebi F, Isobe M, Kurosawa N. Development and validation of monoclonal antibodies against N6-methyladenosine for the detection of RNA modifications. PLoS ONE. 2019;14:e0223197 pubmed publisher
Chen Y, Chen R, Ahmad S, Verma R, Kasturi S, Amaya L, et al. N6-Methyladenosine Modification Controls Circular RNA Immunity. Mol Cell. 2019;: pubmed publisher
Konno M, Koseki J, Asai A, Yamagata A, Shimamura T, Motooka D, et al. Distinct methylation levels of mature microRNAs in gastrointestinal cancers. Nat Commun. 2019;10:3888 pubmed publisher
Chokkalla A, Mehta S, Kim T, Chelluboina B, Kim J, Vemuganti R. Transient Focal Ischemia Significantly Alters the m6A Epitranscriptomic Tagging of RNAs in the Brain. Stroke. 2019;50:2912-2921 pubmed publisher
Miao Z, Zhang T, Qi Y, Song J, Han Z, Ma C. Evolution of the RNA N6-methyladenosine methylome mediated by genomic duplication. Plant Physiol. 2019;: pubmed publisher
Jin H, Ying X, Que B, Wang X, Chao Y, Zhang H, et al. N6-methyladenosine modification of ITGA6 mRNA promotes the development and progression of bladder cancer. EBioMedicine. 2019;47:195-207 pubmed publisher
Zhou L, Tian S, Qin G. RNA methylomes reveal the m6A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening. Genome Biol. 2019;20:156 pubmed publisher
Bushkin G, Pincus D, Morgan J, Richardson K, Lewis C, Chan S, et al. m6A modification of a 3' UTR site reduces RME1 mRNA levels to promote meiosis. Nat Commun. 2019;10:3414 pubmed publisher
Huang T, Guo J, Lv Y, Zheng Y, Feng T, Gao Q, et al. Meclofenamic acid represses spermatogonial proliferation through modulating m6A RNA modification. J Anim Sci Biotechnol. 2019;10:63 pubmed publisher
Garcia Campos M, Edelheit S, Toth U, Safra M, Shachar R, Viukov S, et al. Deciphering the "m6A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019;: pubmed publisher
Yang S, Wei J, Cui Y, Park G, Shah P, Deng Y, et al. m6A mRNA demethylase FTO regulates melanoma tumorigenicity and response to anti-PD-1 blockade. Nat Commun. 2019;10:2782 pubmed publisher
Li T, Hu P, Zuo Z, Lin J, Li X, Wu Q, et al. METTL3 facilitates tumor progression via an m6A-IGF2BP2-dependent mechanism in colorectal carcinoma. Mol Cancer. 2019;18:112 pubmed publisher
Kwon J, Jo Y, Namgoong S, Kim N. Functional roles of hnRNPA2/B1 regulated by METTL3 in mammalian embryonic development. Sci Rep. 2019;9:8640 pubmed publisher
Fan Y, Zhang C, Zhu G. Profiling of RNA N6-methyladenosine methylation during follicle selection in chicken ovary. Poult Sci. 2019;: pubmed publisher
Pontier D, Picart C, El Baidouri M, Roudier F, Xu T, Lahmy S, et al. The m6A pathway protects the transcriptome integrity by restricting RNA chimera formation in plants. Life Sci Alliance. 2019;2: pubmed publisher
Zhao J, Lee E, Kim J, Yang R, Chamseddin B, Ni C, et al. Transforming activity of an oncoprotein-encoding circular RNA from human papillomavirus. Nat Commun. 2019;10:2300 pubmed publisher
Zhang F, Zhang Y, Liao J, Yu Y, Zhou Y, Feng Y, et al. The subunit of RNA N6-methyladenosine methyltransferase OsFIP regulates early degeneration of microspores in rice. PLoS Genet. 2019;15:e1008120 pubmed publisher
Beh L, Debelouchina G, Clay D, Thompson R, Lindblad K, Hutton E, et al. Identification of a DNA N6-Adenine Methyltransferase Complex and Its Impact on Chromatin Organization. Cell. 2019;: pubmed publisher
Huang T, Chen W, Liu J, Gu N, Zhang R. Genome-wide identification of mRNA 5-methylcytosine in mammals. Nat Struct Mol Biol. 2019;: pubmed publisher
Wang H, Hu X, Huang M, Liu J, Gu Y, Ma L, et al. Mettl3-mediated mRNA m6A methylation promotes dendritic cell activation. Nat Commun. 2019;10:1898 pubmed publisher
Zhang J, Bai R, Li M, Ye H, Wu C, Wang C, et al. Excessive miR-25-3p maturation via N6-methyladenosine stimulated by cigarette smoke promotes pancreatic cancer progression. Nat Commun. 2019;10:1858 pubmed publisher
Huang Y, Su R, Sheng Y, Dong L, Dong Z, Xu H, et al. Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia. Cancer Cell. 2019;35:677-691.e10 pubmed publisher
Selberg S, Blokhina D, Aatonen M, Koivisto P, Siltanen A, Mervaala E, et al. Discovery of Small Molecules that Activate RNA Methylation through Cooperative Binding to the METTL3-14-WTAP Complex Active Site. Cell Rep. 2019;26:3762-3771.e5 pubmed publisher
Wang Y, Mao J, Wang X, Lin Y, Hou G, Zhu J, et al. Genome-wide screening of altered m6A-tagged transcript profiles in the hippocampus after traumatic brain injury in mice. Epigenomics. 2019;11:805-819 pubmed publisher
Song H, Feng X, Zhang H, Luo Y, Huang J, Lin M, et al. METTL3 and ALKBH5 oppositely regulate m6A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes. Autophagy. 2019;: pubmed publisher
Zhuang M, Li X, Zhu J, Zhang J, Niu F, Liang F, et al. The m6A reader YTHDF1 regulates axon guidance through translational control of Robo3.1 expression. Nucleic Acids Res. 2019;47:4765-4777 pubmed publisher
Mauer J, Sindelar M, Despic V, Guez T, Hawley B, Vasseur J, et al. FTO controls reversible m6Am RNA methylation during snRNA biogenesis. Nat Chem Biol. 2019;15:340-347 pubmed publisher
McIntyre A, Alexander N, Grigorev K, Bezdan D, Sichtig H, Chiu C, et al. Single-molecule sequencing detection of N6-methyladenine in microbial reference materials. Nat Commun. 2019;10:579 pubmed publisher
Cheng M, Sheng L, Gao Q, Xiong Q, Zhang H, Wu M, et al. The m6A methyltransferase METTL3 promotes bladder cancer progression via AFF4/NF-κB/MYC signaling network. Oncogene. 2019;38:3667-3680 pubmed publisher
Tirumuru N, Wu L. HIV-1 envelope proteins up-regulate N 6-methyladenosine levels of cellular RNA independently of viral replication. J Biol Chem. 2019;294:3249-3260 pubmed publisher
Mishima E, Abe T. Immuno-Northern Blotting: Detection of Modified RNA Using Gel Separation and Antibodies to Modified Nucleosides. Methods Mol Biol. 2019;1870:179-187 pubmed publisher
Jiang Q, Sun B, Liu Q, Cai M, Wu R, Wang F, et al. MTCH2 promotes adipogenesis in intramuscular preadipocytes via an m6A-YTHDF1-dependent mechanism. FASEB J. 2019;33:2971-2981 pubmed publisher
Boileau E, Dieterich C. RNA Modification Level Estimation with pulseR. Genes (Basel). 2018;9: pubmed publisher
Zhang P, He Q, Lei Y, Li Y, Wen X, Hong M, et al. m6A-mediated ZNF750 repression facilitates nasopharyngeal carcinoma progression. Cell Death Dis. 2018;9:1169 pubmed publisher
Sobecki M, Souaid C, Boulay J, Guerineau V, Noordermeer D, Crabbe L. MadID, a Versatile Approach to Map Protein-DNA Interactions, Highlights Telomere-Nuclear Envelope Contact Sites in Human Cells. Cell Rep. 2018;25:2891-2903.e5 pubmed publisher
Luo G, Hao Z, Luo L, Shen M, Sparvoli D, Zheng Y, et al. N6-methyldeoxyadenosine directs nucleosome positioning in Tetrahymena DNA. Genome Biol. 2018;19:200 pubmed publisher
Wu Y, Xie L, Wang M, Xiong Q, Guo Y, Liang Y, et al. Mettl3-mediated m6A RNA methylation regulates the fate of bone marrow mesenchymal stem cells and osteoporosis. Nat Commun. 2018;9:4772 pubmed publisher
Zhong X, Yu J, Frazier K, Weng X, Li Y, Cham C, et al. Circadian Clock Regulation of Hepatic Lipid Metabolism by Modulation of m6A mRNA Methylation. Cell Rep. 2018;25:1816-1828.e4 pubmed publisher
Koh C, Goh Y, Toh J, Neo S, Ng S, Gunaratne J, et al. Single-nucleotide-resolution sequencing of human N6-methyldeoxyadenosine reveals strand-asymmetric clusters associated with SSBP1 on the mitochondrial genome. Nucleic Acids Res. 2018;46:11659-11670 pubmed publisher
Shi H, Zhang X, Weng Y, Lu Z, Liu Y, Lu Z, et al. m6A facilitates hippocampus-dependent learning and memory through YTHDF1. Nature. 2018;563:249-253 pubmed publisher
Xie Q, Wu T, Gimple R, Li Z, Prager B, Wu Q, et al. N6-methyladenine DNA Modification in Glioblastoma. Cell. 2018;175:1228-1243.e20 pubmed publisher
Anderson S, Kramer M, Gosai S, Yu X, Vandivier L, Nelson A, et al. N6-Methyladenosine Inhibits Local Ribonucleolytic Cleavage to Stabilize mRNAs in Arabidopsis. Cell Rep. 2018;25:1146-1157.e3 pubmed publisher
Yan F, Al Kali A, Zhang Z, Liu J, Pang J, Zhao N, et al. A dynamic N6-methyladenosine methylome regulates intrinsic and acquired resistance to tyrosine kinase inhibitors. Cell Res. 2018;28:1062-1076 pubmed publisher
Choe J, Lin S, Zhang W, Liu Q, Wang L, Ramírez Moya J, et al. mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis. Nature. 2018;561:556-560 pubmed publisher
Zeng Y, Wang S, Gao S, Soares F, Ahmed M, Guo H, et al. Refined RIP-seq protocol for epitranscriptome analysis with low input materials. PLoS Biol. 2018;16:e2006092 pubmed publisher
Mendel M, Chen K, Homolka D, Gos P, Pandey R, McCarthy A, et al. Methylation of Structured RNA by the m6A Writer METTL16 Is Essential for Mouse Embryonic Development. Mol Cell. 2018;71:986-1000.e11 pubmed publisher
Yao B, Li Y, Wang Z, Chen L, Poidevin M, Zhang C, et al. Active N6-Methyladenine Demethylation by DMAD Regulates Gene Expression by Coordinating with Polycomb Protein in Neurons. Mol Cell. 2018;71:848-857.e6 pubmed publisher
Li Z, Qian P, Shao W, Shi H, He X, Gogol M, et al. Suppression of m6A reader Ythdf2 promotes hematopoietic stem cell expansion. Cell Res. 2018;28:904-917 pubmed publisher
Zhou C, Wang C, Liu H, Zhou Q, Liu Q, Guo Y, et al. Identification and analysis of adenine N6-methylation sites in the rice genome. Nat Plants. 2018;4:554-563 pubmed publisher
Koranda J, Dore L, Shi H, Patel M, Vaasjo L, Rao M, et al. Mettl14 Is Essential for Epitranscriptomic Regulation of Striatal Function and Learning. Neuron. 2018;99:283-292.e5 pubmed publisher
Engel M, Eggert C, Kaplick P, Eder M, Röh S, Tietze L, et al. The Role of m6A/m-RNA Methylation in Stress Response Regulation. Neuron. 2018;99:389-403.e9 pubmed publisher
Liu B, Merriman D, Choi S, Schumacher M, Plangger R, Kreutz C, et al. A potentially abundant junctional RNA motif stabilized by m6A and Mg2. Nat Commun. 2018;9:2761 pubmed publisher
Xiao C, Zhu S, He M, Chen D, Zhang Q, Chen Y, et al. N6-Methyladenine DNA Modification in the Human Genome. Mol Cell. 2018;71:306-318.e7 pubmed publisher
Merkurjev D, Hong W, Iida K, Oomoto I, Goldie B, Yamaguti H, et al. Synaptic N6-methyladenosine (m6A) epitranscriptome reveals functional partitioning of localized transcripts. Nat Neurosci. 2018;21:1004-1014 pubmed publisher
Martin Carli J, LeDuc C, Zhang Y, Stratigopoulos G, Leibel R. FTO mediates cell-autonomous effects on adipogenesis and adipocyte lipid content by regulating gene expression via 6mA DNA modifications. J Lipid Res. 2018;59:1446-1460 pubmed publisher
Wang C, Cui G, Liu X, Xu K, Wang M, Zhang X, et al. METTL3-mediated m6A modification is required for cerebellar development. PLoS Biol. 2018;16:e2004880 pubmed publisher
Liang Z, Shen L, Cui X, Bao S, Geng Y, Yu G, et al. DNA N6-Adenine Methylation in Arabidopsis thaliana. Dev Cell. 2018;45:406-416.e3 pubmed publisher
Min K, Zealy R, Davila S, Fomin M, Cummings J, Makowsky D, et al. Profiling of m6A RNA modifications identified an age-associated regulation of AGO2 mRNA stability. Aging Cell. 2018;17:e12753 pubmed publisher
Wen J, Lv R, Ma H, Shen H, He C, Wang J, et al. Zc3h13 Regulates Nuclear RNA m6A Methylation and Mouse Embryonic Stem Cell Self-Renewal. Mol Cell. 2018;69:1028-1038.e6 pubmed publisher
Knuckles P, Lence T, Haussmann I, Jacob D, Kreim N, Carl S, et al. Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m6A machinery component Wtap/Fl(2)d. Genes Dev. 2018;32:415-429 pubmed publisher
Yang D, Qiao J, Wang G, Lan Y, Li G, Guo X, et al. N6-Methyladenosine modification of lincRNA 1281 is critically required for mESC differentiation potential. Nucleic Acids Res. 2018;46:3906-3920 pubmed publisher
Du Y, Hou G, Zhang H, Dou J, He J, Guo Y, et al. SUMOylation of the m6A-RNA methyltransferase METTL3 modulates its function. Nucleic Acids Res. 2018;46:5195-5208 pubmed publisher
Bertero A, Brown S, Madrigal P, Osnato A, Ortmann D, Yiangou L, et al. The SMAD2/3 interactome reveals that TGFβ controls m6A mRNA methylation in pluripotency. Nature. 2018;555:256-259 pubmed publisher
Wang X, Sun B, Jiang Q, Wu R, Cai M, Yao Y, et al. mRNA m6A plays opposite role in regulating UCP2 and PNPLA2 protein expression in adipocytes. Int J Obes (Lond). 2018;42:1912-1924 pubmed publisher
Huang H, Weng H, Sun W, Qin X, Shi H, Wu H, et al. Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nat Cell Biol. 2018;20:285-295 pubmed publisher
Tsai K, Courtney D, Cullen B. Addition of m6A to SV40 late mRNAs enhances viral structural gene expression and replication. PLoS Pathog. 2018;14:e1006919 pubmed publisher
Zhou J, Wan J, Shu X, Mao Y, Liu X, Yuan X, et al. N6-Methyladenosine Guides mRNA Alternative Translation during Integrated Stress Response. Mol Cell. 2018;69:636-647.e7 pubmed publisher
Li J, Meng S, Xu M, Wang S, He L, Xu X, et al. Downregulation of N6-methyladenosine binding YTHDF2 protein mediated by miR-493-3p suppresses prostate cancer by elevating N6-methyladenosine levels. Oncotarget. 2018;9:3752-3764 pubmed publisher
Ni T, Elman J, Jin D, Gupta P, Kuperwasser C. Premature polyadenylation of MAGI3 is associated with diminished N6-methyladenosine in its large internal exon. Sci Rep. 2018;8:1415 pubmed publisher
Weng Y, Wang X, An R, Cassin J, Vissers C, Liu Y, et al. Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System. Neuron. 2018;97:313-325.e6 pubmed publisher
Wang Y, Li Y, Yue M, Wang J, Kumar S, Wechsler Reya R, et al. N6-methyladenosine RNA modification regulates embryonic neural stem cell self-renewal through histone modifications. Nat Neurosci. 2018;21:195-206 pubmed publisher
Weng H, Huang H, Wu H, Qin X, Zhao B, Dong L, et al. METTL14 Inhibits Hematopoietic Stem/Progenitor Differentiation and Promotes Leukemogenesis via mRNA m6A Modification. Cell Stem Cell. 2018;22:191-205.e9 pubmed publisher
Tan B, Liu H, Zhang S, da Silva S, Zhang L, Meng J, et al. Viral and cellular N6-methyladenosine and N6,2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018;3:108-120 pubmed publisher
Wang X, Li Z, Kong B, Song C, Cong J, Hou J, et al. Reduced m6A mRNA methylation is correlated with the progression of human cervical cancer. Oncotarget. 2017;8:98918-98930 pubmed publisher
Wang Y, Chen X, Sheng Y, Liu Y, Gao S. N6-adenine DNA methylation is associated with the linker DNA of H2A.Z-containing well-positioned nucleosomes in Pol II-transcribed genes in Tetrahymena. Nucleic Acids Res. 2017;45:11594-11606 pubmed publisher
Yoon K, Ringeling F, Vissers C, Jacob F, Pokrass M, Jimenez Cyrus D, et al. Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation. Cell. 2017;171:877-889.e17 pubmed publisher
Martínez Pérez M, Aparicio F, Lopez Gresa M, Bellés J, Sánchez Navarro J, Pallas V. Arabidopsis m6A demethylase activity modulates viral infection of a plant virus and the m6A abundance in its genomic RNAs. Proc Natl Acad Sci U S A. 2017;114:10755-10760 pubmed publisher
Kudou K, Komatsu T, Nogami J, Maehara K, Harada A, Saeki H, et al. The requirement of Mettl3-promoted MyoD mRNA maintenance in proliferative myoblasts for skeletal muscle differentiation. Open Biol. 2017;7: pubmed publisher
Zhou C, Molinie B, Daneshvar K, Pondick J, Wang J, Van Wittenberghe N, et al. Genome-Wide Maps of m6A circRNAs Identify Widespread and Cell-Type-Specific Methylation Patterns that Are Distinct from mRNAs. Cell Rep. 2017;20:2262-2276 pubmed publisher
Pendleton K, Chen B, Liu K, Hunter O, Xie Y, Tu B, et al. The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention. Cell. 2017;169:824-835.e14 pubmed publisher
Tao X, Chen J, Jiang Y, Wei Y, Chen Y, Xu H, et al. Transcriptome-wide N 6 -methyladenosine methylome profiling of porcine muscle and adipose tissues reveals a potential mechanism for transcriptional regulation and differential methylation pattern. BMC Genomics. 2017;18:336 pubmed publisher
Legnini I, Di Timoteo G, Rossi F, Morlando M, Briganti F, Sthandier O, et al. Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis. Mol Cell. 2017;66:22-37.e9 pubmed publisher
Zhang S, Zhao B, Zhou A, Lin K, Zheng S, Lu Z, et al. m6A Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program. Cancer Cell. 2017;31:591-606.e6 pubmed publisher
Cui Q, Shi H, Ye P, Li L, Qu Q, Sun G, et al. m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells. Cell Rep. 2017;18:2622-2634 pubmed publisher
Zhao B, Wang X, Beadell A, Lu Z, Shi H, Kuuspalu A, et al. m6A-dependent maternal mRNA clearance facilitates zebrafish maternal-to-zygotic transition. Nature. 2017;542:475-478 pubmed publisher
Koziol M, Bradshaw C, Allen G, Costa A, Frezza C. Identification of Methylated Deoxyadenosines in Genomic DNA by dA6m DNA Immunoprecipitation. Bio Protoc. 2016;6: pubmed publisher
Zhou C, Liu Y, Li X, Zou J, Zou S. DNA N6-methyladenine demethylase ALKBH1 enhances osteogenic differentiation of human MSCs. Bone Res. 2016;4:16033 pubmed
Liu J, Zhu Y, Luo G, Wang X, Yue Y, Wang X, et al. Abundant DNA 6mA methylation during early embryogenesis of zebrafish and pig. Nat Commun. 2016;7:13052 pubmed publisher
Zhang C, Zhi W, Lu H, Samanta D, Chen I, Gabrielson E, et al. Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells. Oncotarget. 2016;7:64527-64542 pubmed publisher
Du H, Zhao Y, He J, Zhang Y, Xi H, Liu M, et al. YTHDF2 destabilizes m(6)A-containing RNA through direct recruitment of the CCR4-NOT deadenylase complex. Nat Commun. 2016;7:12626 pubmed publisher
Li X, Yang J, Zhu Y, Liu Y, Shi X, Yang G. Mouse Maternal High-Fat Intake Dynamically Programmed mRNA m?A Modifications in Adipose and Skeletal Muscle Tissues in Offspring. Int J Mol Sci. 2016;17: pubmed publisher
Molinie B, Wang J, Lim K, Hillebrand R, Lu Z, Van Wittenberghe N, et al. m(6)A-LAIC-seq reveals the census and complexity of the m(6)A epitranscriptome. Nat Methods. 2016;13:692-8 pubmed publisher
Tirumuru N, Zhao B, Lu W, Lu Z, He C, Wu L. N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression. elife. 2016;5: pubmed publisher
Lin S, Choe J, Du P, Triboulet R, Gregory R. The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells. Mol Cell. 2016;62:335-345 pubmed publisher
Koziol M, Bradshaw C, Allen G, Costa A, Frezza C, Gurdon J. Identification of methylated deoxyadenosines in vertebrates reveals diversity in DNA modifications. Nat Struct Mol Biol. 2016;23:24-30 pubmed publisher
product information
Cat. Nr. :
202 003
Antigen :
m6A
Synonyms :
N6-methyladenosine, Adenosine
Host Species :
rabbit
Tpye :
polyclonal
Form :
affinity purified
Immunogen :
N6-methyladenosine fused to BSA.
Reactivity :
human, rat, mouse, eukaryotes, prokaryotes
WB :
WB
IP :
IP
ICC :
ICC
IHC P :
IHC-P
ELISA :
ELISA
Quantity :
50 µg
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany