product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
P2X7
catalog :
177 003
quantity :
50 µg
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
/
reactivity :
human, mouse
application :
western blot, immunohistochemistry - frozen section
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - frozen section; mouse; fig 1
  • western blot; mouse; fig 1
Sinadinos A, Young C, Al Khalidi R, Teti A, Kalinski P, Mohamad S, et al. P2RX7 purinoceptor: a therapeutic target for ameliorating the symptoms of duchenne muscular dystrophy. PLoS Med. 2015;12:e1001888 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 4c
  • western blot; mouse; 1:1000; loading ...; fig 3a
Young C, Sinadinos A, Lefebvre A, Chan P, Arkle S, Vaudry D, et al. A novel mechanism of autophagic cell death in dystrophic muscle regulated by P2RX7 receptor large-pore formation and HSP90. Autophagy. 2015;11:113-30 pubmed publisher
Kaczmarek Hájek K, Zhang J, Kopp R, Grosche A, Rissiek B, Saul A, et al. Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody. elife. 2018;7: pubmed publisher
Young C, Chira N, Róg J, Al Khalidi R, Benard M, Galas L, et al. Sustained activation of P2X7 induces MMP-2-evoked cleavage and functional purinoceptor inhibition. J Mol Cell Biol. 2018;10:229-242 pubmed publisher
Masin M, Young C, Lim K, Barnes S, Xu X, Marschall V, et al. Expression, assembly and function of novel C-terminal truncated variants of the mouse P2X7 receptor: re-evaluation of P2X7 knockouts. Br J Pharmacol. 2012;165:978-93 pubmed publisher
Young C, Brutkowski W, Lien C, Arkle S, Lochm ller H, Zab ocki K, et al. P2X7 purinoceptor alterations in dystrophic mdx mouse muscles: relationship to pathology and potential target for treatment. J Cell Mol Med. 2012;16:1026-37 pubmed publisher
product information
Company Name :
Synaptic Systems
Cat. Nr. :
177 003
Antigen :
P2X7
Host Species :
rabbit
Tpye :
polyclonal
Form :
affinity purified
Immunogen :
Recombinant protein corresponding to AA 363 to 595 from mouse P2X7 (UniProt Id: Q9Z1M0)
Reactivity :
rat, mouse
WB :
y
IP :
?
ICC :
?
IHC :
?
IHC P :
?
KO :
1
Quantity :
50 µg
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany