product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
Neurofilament L
catalog :
171 002
quantity :
200 µl
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
clone name :
/
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:500; fig 1
  • western blot; human; 1:500; fig 4
Patzke C, Acuna C, Giam L, Wernig M, Südhof T. Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation. J Exp Med. 2016;213:499-515 pubmed publisher
Koppel N, Friese M, Cardasis H, Neubert T, Burden S. Vezatin is required for the maturation of the neuromuscular synapse. Mol Biol Cell. 2019;30:2571-2583 pubmed publisher
Oury J, Liu Y, Topf A, Todorovic S, Hoedt E, Preethish Kumar V, et al. MACF1 links Rapsyn to microtubule- and actin-binding proteins to maintain neuromuscular synapses. J Cell Biol. 2019;218:1686-1705 pubmed publisher
Schöniger S, Schütze E, Michalski D, Puchta J, Kaiser M, Hartig W. Neuropathological findings suggestive for a stroke in an alpaca (Vicugna pacos). Acta Vet Scand. 2019;61:1 pubmed publisher
Mages B, Aleithe S, Altmann S, Blietz A, Nitzsche B, Barthel H, et al. Impaired Neurofilament Integrity and Neuronal Morphology in Different Models of Focal Cerebral Ischemia and Human Stroke Tissue. Front Cell Neurosci. 2018;12:161 pubmed publisher
Richter K, Revelo N, Seitz K, Helm M, Sarkar D, Saleeb R, et al. Glyoxal as an alternative fixative to formaldehyde in immunostaining and super-resolution microscopy. EMBO J. 2018;37:139-159 pubmed publisher
Edmond M, Hanley O, Philippidou P. Topoisomerase IIβ Selectively Regulates Motor Neuron Identity and Peripheral Connectivity through Hox/Pbx-Dependent Transcriptional Programs. Eneuro. 2017;4: pubmed publisher
Hartig W, Krueger M, Hofmann S, Preißler H, Märkel M, Frydrychowicz C, et al. Up-regulation of neurofilament light chains is associated with diminished immunoreactivities for MAP2 and tau after ischemic stroke in rodents and in a human case. J Chem Neuroanat. 2016;78:140-148 pubmed publisher
product information
Cat. Nr. :
171 002
Antigen :
Neurofilament L
Synonyms :
NF-L, NF68, NFL, NeurofilamentH
Host Species :
rabbit
Tpye :
polyclonal
Form :
antiserum
Immunogen :
Recombinant protein corresponding to AA 1 to 376 from human Neurofilament L (UniProt Id: P07196) with AA 200-292 missing. Immunogen corresponds to AA 1 to 284 in NBCI: AAH66952.1
Reactivity :
human, rat, mouse
WB :
WB
IP :
IP
ICC :
ICC
IHC :
IHC
IHC P :
IHC-P
Quantity :
200 µl
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany