product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
Rab 27 B
catalog :
168 103
quantity :
50 µg
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
clone name :
/
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
Synaptic Systems product webpage
citations: 7
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 5-10 ug/ml; loading ...; fig 3a
Woo S, James D, Martin T. Munc13-4 functions as a Ca2+ sensor for homotypic secretory granule fusion to generate endosomal exocytic vacuoles. Mol Biol Cell. 2017;28:792-808 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:4000
  • immunocytochemistry; mouse; 1:4000
  • western blot; mouse; 1:4000
Hou Y, Ernst S, Stuenkel E, Lentz S, Williams J. Rab27A Is Present in Mouse Pancreatic Acinar Cells and Is Required for Digestive Enzyme Secretion. PLoS ONE. 2015;10:e0125596 pubmed publisher
Yoon S, Kovalenko A, Bogdanov K, Wallach D. MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation. Immunity. 2017;47:51-65.e7 pubmed publisher
Shen Y, Gu Y, Su W, Zhong J, Jin Z, Gu X, et al. Rab27b is Involved in Lysosomal Exocytosis and Proteolipid Protein Trafficking in Oligodendrocytes. Neurosci Bull. 2016;32:331-40 pubmed publisher
Hou Y, Ernst S, Lentz S, Williams J. Genetic deletion of Rab27B in pancreatic acinar cells affects granules size and has inhibitory effects on amylase secretion. Biochem Biophys Res Commun. 2016;471:610-5 pubmed publisher
Hou Y, Chen X, Tolmachova T, Ernst S, Williams J. EPI64B acts as a GTPase-activating protein for Rab27B in pancreatic acinar cells. J Biol Chem. 2013;288:19548-57 pubmed publisher
Pavlos N, Gr Nborg M, Riedel D, Chua J, Boyken J, Kloepper T, et al. Quantitative analysis of synaptic vesicle Rabs uncovers distinct yet overlapping roles for Rab3a and Rab27b in Ca2+-triggered exocytosis. J Neurosci. 2010;30:13441-53 pubmed publisher
product information
Company Name :
Synaptic Systems
Cat. Nr. :
168 103
Antigen :
Rab 27 B
Synonyms :
Rab 27A, Rab 27B, rab27, rab27a
Host Species :
rabbit
Tpye :
polyclonal
Form :
affinity purified 3
Immunogen :
Recombinant protein corresponding to AA 1 to 217 from rat Rab27B (UniProt Id: Q99P74)
Reactivity :
rat, mouse, human
WB :
y
IP :
y
ICC :
y
IHC :
y
IHC P :
y
KO :
1
KD :
1
Quantity :
50 µg
more info or order :
Synaptic Systems product webpage
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany