product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
Homer 1
catalog :
160 011
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2G8
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; 1:1000; loading ...; fig 4j
Sloan S, Darmanis S, Huber N, Khan T, Birey F, Caneda C, et al. Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells. Neuron. 2017;95:779-790.e6 pubmed publisher
  • immunocytochemistry; mouse; fig 4
  • western blot; mouse; fig 2
Bodaleo F, Montenegro Venegas C, Henríquez D, Court F, Gonzalez Billault C. Microtubule-associated protein 1B (MAP1B)-deficient neurons show structural presynaptic deficiencies in vitro and altered presynaptic physiology. Sci Rep. 2016;6:30069 pubmed publisher
  • western blot; mouse; fig 7
Frank R, Komiyama N, Ryan T, Zhu F, O Dell T, Grant S. NMDA receptors are selectively partitioned into complexes and supercomplexes during synapse maturation. Nat Commun. 2016;7:11264 pubmed publisher
  • immunohistochemistry; mouse; loading ...; fig 4a
Hong S, Beja Glasser V, Nfonoyim B, Frouin A, Li S, Ramakrishnan S, et al. Complement and microglia mediate early synapse loss in Alzheimer mouse models. Science. 2016;352:712-716 pubmed publisher
  • immunohistochemistry; mouse; fig 1
Gazit N, Vertkin I, Shapira I, Helm M, Slomowitz E, Sheiba M, et al. IGF-1 Receptor Differentially Regulates Spontaneous and Evoked Transmission via Mitochondria at Hippocampal Synapses. Neuron. 2016;89:583-97 pubmed publisher
Finelli M, Aprile D, Castroflorio E, Jeans A, Moschetta M, Chessum L, et al. The epilepsy-associated protein TBC1D24 is required for normal development, survival and vesicle trafficking in mammalian neurons. Hum Mol Genet. 2019;28:584-597 pubmed publisher
Pothayee N, Maric D, Sharer K, Tao Cheng J, Calac A, Bouraoud N, et al. Neural precursor cells form integrated brain-like tissue when implanted into rat cerebrospinal fluid. Commun Biol. 2018;1:114 pubmed publisher
Oh J, Lim C, Yoo K, Park H, Park Y, Kim E, et al. Adenomatous polyposis coli-stimulated GEF 1 (Asef1) is a negative regulator of excitatory synaptic function. J Neurochem. 2018;147:595-608 pubmed publisher
Park S, Kang W, Kwon Y, Shim J, Kim S, Kaang B, et al. Superresolution fluorescence microscopy for 3D reconstruction of thick samples. Mol Brain. 2018;11:17 pubmed publisher
Krencik R, Seo K, van Asperen J, Basu N, Cvetkovic C, Barlas S, et al. Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes. Stem Cell Reports. 2017;9:1745-1753 pubmed publisher
Dunn C, Sarkar P, Bailey E, Farris S, Zhao M, Ward J, et al. Histone Hypervariants H2A.Z.1 and H2A.Z.2 Play Independent and Context-Specific Roles in Neuronal Activity-Induced Transcription of Arc/Arg3.1 and Other Immediate Early Genes. Eneuro. 2017;4: pubmed publisher
Hayashi S, Inoue Y, Hattori S, Kaneko M, Shioi G, Miyakawa T, et al. Loss of X-linked Protocadherin-19 differentially affects the behavior of heterozygous female and hemizygous male mice. Sci Rep. 2017;7:5801 pubmed publisher
Chang J, Chen F, Yoon Y, Jung E, Babcock H, Kang J, et al. Iterative expansion microscopy. Nat Methods. 2017;14:593-599 pubmed publisher
Altmüller F, Pothula S, Annamneedi A, Nakhaei Rad S, Montenegro Venegas C, Pina Fernández E, et al. Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy. PLoS Genet. 2017;13:e1006684 pubmed publisher
Chiacchiaretta M, Latifi S, Bramini M, Fadda M, Fassio A, Benfenati F, et al. Neuronal hyperactivity causes Na+/H+ exchanger-induced extracellular acidification at active synapses. J Cell Sci. 2017;130:1435-1449 pubmed publisher
Tao Cheng J, Azzam R, Crocker V, Winters C, Reese T. Depolarization of Hippocampal Neurons Induces Formation of Nonsynaptic NMDA Receptor Islands Resembling Nascent Postsynaptic Densities. Eneuro. 2015;2: pubmed publisher
Jaudon F, Raynaud F, Wehrlé R, Bellanger J, Doulazmi M, Vodjdani G, et al. The RhoGEF DOCK10 is essential for dendritic spine morphogenesis. Mol Biol Cell. 2015;26:2112-27 pubmed publisher
Ivanova D, Dirks A, Montenegro Venegas C, Schöne C, Altrock W, Marini C, et al. Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo. EMBO J. 2015;34:1056-77 pubmed publisher
Tao Cheng J, Yang Y, Bayer K, Reese T, Dosemeci A. NMDA-induced accumulation of Shank at the postsynaptic density is mediated by CaMKII. Biochem Biophys Res Commun. 2014;450:808-11 pubmed publisher
Tao Cheng J, Thein S, Yang Y, Reese T, Gallant P. Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation. Neuroscience. 2014;266:80-90 pubmed publisher
Lauks J, Klemmer P, Farzana F, Karupothula R, Zalm R, Cooke N, et al. Synapse associated protein 102 (SAP102) binds the C-terminal part of the scaffolding protein neurobeachin. PLoS ONE. 2012;7:e39420 pubmed publisher
product information
Company Name :
Synaptic Systems
Cat. Nr. :
160 011
Antigen :
Homer 1
Synonyms :
VesL 1, Syn47, Homer 1, Homer 1a, Homer1
Host Species :
mouse
Tpye :
monoclonal
Form :
purified IgG
Cell Line :
2G8
Subtype :
IgG1
Immunogen :
Recombinant protein corresponding to AA 1 to 196 from human Homer1 (UniProt Id: Q86YM7)
Reactivity :
human, rat, mouse
WB :
y
IP :
y
ICC :
y
IHC :
no
IHC P :
?
EM :
y
ELISA :
y
Quantity :
100 µg
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany