product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
Gephyrin
catalog :
147 011
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
mAb7a
reactivity :
human, mouse, rat, zebrafish
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - frozen section, immunohistochemistry - free floating section
more info or order :
citations: 119
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; loading ...; fig 1d
Mukherjee A, Carvalho F, Eliez S, Caroni P. Long-Lasting Rescue of Network and Cognitive Dysfunction in a Genetic Schizophrenia Model. Cell. 2019;178:1387-1402.e14 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig s1h
Awasthi A, Ramachandran B, Ahmed S, Benito E, Shinoda Y, Nitzan N, et al. Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting. Science. 2019;363: pubmed publisher
  • immunohistochemistry; rat; 1:500; loading ...; fig 2b
Wigerius M, Quinn D, Diab A, Clattenburg L, Kolar A, Qi J, et al. The polarity protein Angiomotin p130 controls dendritic spine maturation. J Cell Biol. 2018;217:715-730 pubmed publisher
  • immunohistochemistry - frozen section; zebrafish ; 1:500; loading ...; tbl 1
Yan Q, Zhai L, Zhang B, Dallman J. Spatial patterning of excitatory and inhibitory neuropil territories during spinal circuit development. J Comp Neurol. 2017;525:1649-1667 pubmed publisher
  • immunohistochemistry - frozen section; rat; 1:500; loading ...; fig 8
Oh Y, Karube F, Takahashi S, Kobayashi K, Takada M, Uchigashima M, et al. Using a novel PV-Cre rat model to characterize pallidonigral cells and their terminations. Brain Struct Funct. 2017;222:2359-2378 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:5000; loading ...; fig 8a2
  • immunohistochemistry; mouse; 1:5000
Matsuno T, Kiyokage E, Toida K. Synaptic distribution of individually labeled mitral cells in the external plexiform layer of the mouse olfactory bulb. J Comp Neurol. 2017;525:1633-1648 pubmed publisher
  • immunocytochemistry; human; loading ...
Nguyen T, Schreiner D, Xiao L, Traunmüller L, Bornmann C, Scheiffele P. An alternative splicing switch shapes neurexin repertoires in principal neurons versus interneurons in the mouse hippocampus. elife. 2016;5: pubmed publisher
  • immunohistochemistry; mouse; 1:2000; fig 1f
Kilpatrick C, Murakami S, Feng M, Wu X, Lal R, Chen G, et al. Dissociation of Golgi-associated DHHC-type Zinc Finger Protein (GODZ)- and Sertoli Cell Gene with a Zinc Finger Domain-? (SERZ-?)-mediated Palmitoylation by Loss of Function Analyses in Knock-out Mice. J Biol Chem. 2016;291:27371-27386 pubmed publisher
  • immunocytochemistry; rat; 1:1000; loading ...; fig 1e
  • immunohistochemistry; mouse; 1:1000; loading ...; fig s1b
Cai Y, Yang L, Hu G, Chen X, Niu F, Yuan L, et al. Regulation of morphine-induced synaptic alterations: Role of oxidative stress, ER stress, and autophagy. J Cell Biol. 2016;215:245-258 pubmed
  • western blot; mouse; 1:1000; fig s2
Sun X, Li L, Liu F, Huang Z, Bean J, Jiao H, et al. Lrp4 in astrocytes modulates glutamatergic transmission. Nat Neurosci. 2016;19:1010-8 pubmed publisher
  • immunohistochemistry; rat; loading ...; fig 5e
  • western blot; rat; loading ...; fig 2b
Um J, Choii G, Park D, Kim D, Jeon S, Kang H, et al. IQ Motif and SEC7 Domain-containing Protein 3 (IQSEC3) Interacts with Gephyrin to Promote Inhibitory Synapse Formation. J Biol Chem. 2016;291:10119-30 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:300; fig 7
Gao Y, Heldt S. Enrichment of GABAA Receptor α-Subunits on the Axonal Initial Segment Shows Regional Differences. Front Cell Neurosci. 2016;10:39 pubmed publisher
  • immunocytochemistry; rat; 1:500; fig 2
Schoen M, Reichel J, Demestre M, Putz S, Deshpande D, Proepper C, et al. Super-Resolution Microscopy Reveals Presynaptic Localization of the ALS/FTD Related Protein FUS in Hippocampal Neurons. Front Cell Neurosci. 2015;9:496 pubmed publisher
  • immunocytochemistry; rat; 1:500; fig 1
Brigidi G, Santyr B, Shimell J, Jovellar B, Bamji S. Activity-regulated trafficking of the palmitoyl-acyl transferase DHHC5. Nat Commun. 2015;6:8200 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; fig s6
He Q, Duguid I, Clark B, Panzanelli P, Patel B, Thomas P, et al. Interneuron- and GABA(A) receptor-specific inhibitory synaptic plasticity in cerebellar Purkinje cells. Nat Commun. 2015;6:7364 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:700; fig 6
Schwarz L, Miyamichi K, Gao X, BEIER K, Weissbourd B, DeLoach K, et al. Viral-genetic tracing of the input-output organization of a central noradrenaline circuit. Nature. 2015;524:88-92 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:1000; loading ...; fig 3,4
  • immunocytochemistry; rat; 1:500; loading ...; fig 6
Kang Y, Ge Y, Cassidy R, Lam V, Luo L, Moon K, et al. A combined transgenic proteomic analysis and regulated trafficking of neuroligin-2. J Biol Chem. 2014;289:29350-64 pubmed publisher
  • immunocytochemistry; human; 1:300
Brady M, Moon C, Jacob T. Using an ?-bungarotoxin binding site tag to study GABA A receptor membrane localization and trafficking. J Vis Exp. 2014;: pubmed publisher
Halff E, Szulc B, Lesept F, Kittler J. SNX27-Mediated Recycling of Neuroligin-2 Regulates Inhibitory Signaling. Cell Rep. 2019;29:2599-2607.e6 pubmed publisher
Shimell J, Shah B, Cain S, Thouta S, Kuhlmann N, Tatarnikov I, et al. The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation. Cell Rep. 2019;29:2422-2437.e8 pubmed publisher
Fossati M, Assendorp N, Gemin O, Colasse S, Dingli F, Arras G, et al. Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons. Neuron. 2019;: pubmed publisher
Esposito A, Falace A, Wagner M, Gal M, Mei D, Conti V, et al. Biallelic DMXL2 mutations impair autophagy and cause Ohtahara syndrome with progressive course. Brain. 2019;142:3876-3891 pubmed publisher
Gottschling C, Wegrzyn D, Denecke B, Faissner A. Elimination of the four extracellular matrix molecules tenascin-C, tenascin-R, brevican and neurocan alters the ratio of excitatory and inhibitory synapses. Sci Rep. 2019;9:13939 pubmed publisher
Gao X, Grendel J, Muhia M, Castro Gomez S, Süsens U, Isbrandt D, et al. Disturbed prefrontal cortex activity in the absence of schizophrenia-like behavioral dysfunction in Arc/Arg3.1 deficient mice. J Neurosci. 2019;: pubmed publisher
Hu G, Niu F, Liao K, Periyasamy P, Sil S, Liu J, et al. HIV-1 Tat-Induced Astrocytic Extracellular Vesicle miR-7 Impairs Synaptic Architecture. J Neuroimmune Pharmacol. 2019;: pubmed publisher
Acton D, Ren X, Di Costanzo S, Dalet A, Bourane S, Bertocchi I, et al. Spinal Neuropeptide Y1 Receptor-Expressing Neurons Form an Essential Excitatory Pathway for Mechanical Itch. Cell Rep. 2019;28:625-639.e6 pubmed publisher
Kwon Y, Lee S, Lee E, Kim D, Park D. βPix heterozygous mice have defects in neuronal morphology and social interaction. Biochem Biophys Res Commun. 2019;516:1204-1210 pubmed publisher
Marro S, Chanda S, Yang N, Janas J, Valperga G, Trotter J, et al. Neuroligin-4 Regulates Excitatory Synaptic Transmission in Human Neurons. Neuron. 2019;: pubmed publisher
Shah B, Shimell J, Bamji S. Regulation of dendrite morphology and excitatory synapse formation by zDHHC15. J Cell Sci. 2019;: pubmed publisher
Lorenz Guertin J, Bambino M, Das S, Weintraub S, Jacob T. Diazepam Accelerates GABAAR Synaptic Exchange and Alters Intracellular Trafficking. Front Cell Neurosci. 2019;13:163 pubmed publisher
Hu H, Kruijssen D, Frias C, Rozsa B, Hoogenraad C, Wierenga C. Endocannabinoid Signaling Mediates Local Dendritic Coordination between Excitatory and Inhibitory Synapses. Cell Rep. 2019;27:666-675.e5 pubmed publisher
Kroon T, van Hugte E, van Linge L, Mansvelder H, Meredith R. Early postnatal development of pyramidal neurons across layers of the mouse medial prefrontal cortex. Sci Rep. 2019;9:5037 pubmed publisher
Crosby K, Gookin S, Garcia J, Hahm K, Dell Acqua M, Smith K. Nanoscale Subsynaptic Domains Underlie the Organization of the Inhibitory Synapse. Cell Rep. 2019;26:3284-3297.e3 pubmed publisher
Tai Y, Gallo N, Wang M, Yu J, Van Aelst L. Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM. Neuron. 2019;102:358-372.e9 pubmed publisher
Davenport E, Szulc B, Drew J, Taylor J, Morgan T, Higgs N, et al. Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition. Cell Rep. 2019;26:2037-2051.e6 pubmed publisher
Shao Z, Noh H, Bin Kim W, Ni P, Nguyen C, Cote S, et al. Dysregulated protocadherin-pathway activity as an intrinsic defect in induced pluripotent stem cell-derived cortical interneurons from subjects with schizophrenia. Nat Neurosci. 2019;22:229-242 pubmed publisher
Hollnagel J, Elzoheiry S, Gorgas K, Kins S, Beretta C, Kirsch J, et al. Early alterations in hippocampal perisomatic GABAergic synapses and network oscillations in a mouse model of Alzheimer's disease amyloidosis. PLoS ONE. 2019;14:e0209228 pubmed publisher
Dhar M, Hantman A, Nishiyama H. Developmental pattern and structural factors of dendritic survival in cerebellar granule cells in vivo. Sci Rep. 2018;8:17561 pubmed publisher
Dejanovic B, Huntley M, De Mazière A, Meilandt W, Wu T, Srinivasan K, et al. Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies. Neuron. 2018;100:1322-1336.e7 pubmed publisher
Wamsley B, Jaglin X, Favuzzi E, Quattrocolo G, Nigro M, Yusuf N, et al. Rbfox1 Mediates Cell-type-Specific Splicing in Cortical Interneurons. Neuron. 2018;100:846-859.e7 pubmed publisher
Fang C, Wu B, Le N, Imberdis T, Mercer R, Harris D. Prions activate a p38 MAPK synaptotoxic signaling pathway. PLoS Pathog. 2018;14:e1007283 pubmed publisher
Wang X, Zorio D, Schecterson L, Lu Y, Wang Y. Postsynaptic FMRP Regulates Synaptogenesis In Vivo in the Developing Cochlear Nucleus. J Neurosci. 2018;38:6445-6460 pubmed publisher
Jiang D, Wu Z, Forsyth C, Hu Y, Yee S, Chen G. GABAergic deficits and schizophrenia-like behaviors in a mouse model carrying patient-derived neuroligin-2 R215H mutation. Mol Brain. 2018;11:31 pubmed publisher
Lin T, Tan Z, Barik A, Yin D, Brudvik E, Wang H, et al. Regulation of Synapse Development by Vgat Deletion from ErbB4-Positive Interneurons. J Neurosci. 2018;38:2533-2550 pubmed publisher
Ge Y, Kang Y, Cassidy R, Moon K, Lewis R, Wong R, et al. Clptm1 Limits Forward Trafficking of GABAA Receptors to Scale Inhibitory Synaptic Strength. Neuron. 2018;97:596-610.e8 pubmed publisher
Brady M, Pilli J, Lorenz Guertin J, Das S, Moon C, Graff N, et al. Depolarizing, inhibitory GABA type A receptor activity regulates GABAergic synapse plasticity via ERK and BDNF signaling. Neuropharmacology. 2018;128:324-339 pubmed publisher
Skilbeck K, Johnston G, Hinton T. Long-lasting effects of early-life intervention in mice on adulthood behaviour, GABAA receptor subunit expression and synaptic clustering. Pharmacol Res. 2018;128:179-189 pubmed publisher
Liu J, Sanes J. Cellular and Molecular Analysis of Dendritic Morphogenesis in a Retinal Cell Type That Senses Color Contrast and Ventral Motion. J Neurosci. 2017;37:12247-12262 pubmed publisher
de Groot C, Floriou Servou A, Tsai Y, Früh S, Kohler M, Parkin G, et al. RhoGEF9 splice isoforms influence neuronal maturation and synapse formation downstream of ?2 GABAA receptors. PLoS Genet. 2017;13:e1007073 pubmed publisher
Dzyubenko E, Juckel G, Faissner A. The antipsychotic drugs olanzapine and haloperidol modify network connectivity and spontaneous activity of neural networks in vitro. Sci Rep. 2017;7:11609 pubmed publisher
Patrizio A, Renner M, Pizzarelli R, Triller A, Specht C. Alpha subunit-dependent glycine receptor clustering and regulation of synaptic receptor numbers. Sci Rep. 2017;7:10899 pubmed publisher
Heine J, Reuss M, Harke B, D Este E, Sahl S, Hell S. Adaptive-illumination STED nanoscopy. Proc Natl Acad Sci U S A. 2017;114:9797-9802 pubmed publisher
Cantaut Belarif Y, Antri M, Pizzarelli R, Colasse S, Vaccari I, Soares S, et al. Microglia control the glycinergic but not the GABAergic synapses via prostaglandin E2 in the spinal cord. J Cell Biol. 2017;216:2979-2989 pubmed publisher
Favuzzi E, Marques Smith A, Deogracias R, Winterflood C, Sánchez Aguilera A, Mantoan L, et al. Activity-Dependent Gating of Parvalbumin Interneuron Function by the Perineuronal Net Protein Brevican. Neuron. 2017;95:639-655.e10 pubmed publisher
Laperchia C, Imperatore R, Azeez I, Del Gallo F, Bertini G, Grassi Zucconi G, et al. The excitatory/inhibitory input to orexin/hypocretin neuron soma undergoes day/night reorganization. Brain Struct Funct. 2017;222:3847-3859 pubmed publisher
Panzanelli P, Früh S, Fritschy J. Differential role of GABAA receptors and neuroligin 2 for perisomatic GABAergic synapse formation in the hippocampus. Brain Struct Funct. 2017;222:4149-4161 pubmed publisher
Chang J, Chen F, Yoon Y, Jung E, Babcock H, Kang J, et al. Iterative expansion microscopy. Nat Methods. 2017;14:593-599 pubmed publisher
Yamasaki T, Hoyos Ramirez E, Martenson J, Morimoto Tomita M, Tomita S. GARLH Family Proteins Stabilize GABAA Receptors at Synapses. Neuron. 2017;93:1138-1152.e6 pubmed publisher
Pennacchietti F, Vascon S, Nieus T, Rosillo C, Das S, Tyagarajan S, et al. Nanoscale Molecular Reorganization of the Inhibitory Postsynaptic Density Is a Determinant of GABAergic Synaptic Potentiation. J Neurosci. 2017;37:1747-1756 pubmed publisher
Fuchs T, Jefferson S, Hooper A, Yee P, Maguire J, Luscher B. Disinhibition of somatostatin-positive GABAergic interneurons results in an anxiolytic and antidepressant-like brain state. Mol Psychiatry. 2017;22:920-930 pubmed publisher
Dondzillo A, Thompson J, Klug A. Recurrent Inhibition to the Medial Nucleus of the Trapezoid Body in the Mongolian Gerbil (Meriones Unguiculatus). PLoS ONE. 2016;11:e0160241 pubmed publisher
Lenz M, Galanis C, Müller Dahlhaus F, Opitz A, Wierenga C, Szabó G, et al. Repetitive magnetic stimulation induces plasticity of inhibitory synapses. Nat Commun. 2016;7:10020 pubmed publisher
Marshak D, Chuang A, Dolino D, JACOBY R, Liu W, Long Y, et al. Synaptic connections of amacrine cells containing vesicular glutamate transporter 3 in baboon retinas. Vis Neurosci. 2015;32:E006 pubmed publisher
Vullhorst D, Mitchell R, Keating C, Roychowdhury S, Karavanova I, Tao Cheng J, et al. A negative feedback loop controls NMDA receptor function in cortical interneurons via neuregulin 2/ErbB4 signalling. Nat Commun. 2015;6:7222 pubmed publisher
Laht P, Tammaru E, Otsus M, Rohtla J, Tiismus L, Veske A. Plexin-B3 suppresses excitatory and promotes inhibitory synapse formation in rat hippocampal neurons. Exp Cell Res. 2015;335:269-78 pubmed publisher
Varea O, Martín de Saavedra M, Kopeikina K, Schürmann B, Fleming H, Fawcett Patel J, et al. Synaptic abnormalities and cytoplasmic glutamate receptor aggregates in contactin associated protein-like 2/Caspr2 knockout neurons. Proc Natl Acad Sci U S A. 2015;112:6176-81 pubmed publisher
Hausrat T, Muhia M, Gerrow K, Thomas P, Hirdes W, Tsukita S, et al. Radixin regulates synaptic GABAA receptor density and is essential for reversal learning and short-term memory. Nat Commun. 2015;6:6872 pubmed publisher
Deprez F, Pallotto M, Vogt F, Grabiec M, Virtanen M, Tyagarajan S, et al. Postsynaptic gephyrin clustering controls the development of adult-born granule cells in the olfactory bulb. J Comp Neurol. 2015;523:1998-2016 pubmed publisher
Rathgeber L, Gromova K, Schaefer I, Breiden P, Lohr C, Kneussel M. GSK3 and KIF5 regulate activity-dependent sorting of gephyrin between axons and dendrites. Eur J Cell Biol. 2015;94:173-8 pubmed publisher
Papadopoulos T, Schemm R, Grubmüller H, Brose N. Lipid binding defects and perturbed synaptogenic activity of a Collybistin R290H mutant that causes epilepsy and intellectual disability. J Biol Chem. 2015;290:8256-70 pubmed publisher
Bartel D, Rela L, Hsieh L, Greer C. Dendrodendritic synapses in the mouse olfactory bulb external plexiform layer. J Comp Neurol. 2015;523:1145-61 pubmed publisher
Antonelli R, Pizzarelli R, Pedroni A, Fritschy J, Del Sal G, Cherubini E, et al. Pin1-dependent signalling negatively affects GABAergic transmission by modulating neuroligin2/gephyrin interaction. Nat Commun. 2014;5:5066 pubmed publisher
Wang S, Celic I, Choi S, Riccomagno M, Wang Q, Sun L, et al. Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization. J Neurosci. 2014;34:12745-61 pubmed publisher
Lorenzo L, Godin A, Wang F, St Louis M, Carbonetto S, Wiseman P, et al. Gephyrin clusters are absent from small diameter primary afferent terminals despite the presence of GABA(A) receptors. J Neurosci. 2014;34:8300-17 pubmed publisher
Petrini E, Ravasenga T, Hausrat T, Iurilli G, Olcese U, Racine V, et al. Synaptic recruitment of gephyrin regulates surface GABAA receptor dynamics for the expression of inhibitory LTP. Nat Commun. 2014;5:3921 pubmed publisher
Karayannis T, Au E, Patel J, Kruglikov I, Markx S, Delorme R, et al. Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission. Nature. 2014;511:236-40 pubmed
Seifi M, Corteen N, van der Want J, Metzger F, Swinny J. Localization of NG2 immunoreactive neuroglia cells in the rat locus coeruleus and their plasticity in response to stress. Front Neuroanat. 2014;8:31 pubmed publisher
Mishra A, Traut M, Becker L, Klopstock T, Stein V, Klein R. Genetic evidence for the adhesion protein IgSF9/Dasm1 to regulate inhibitory synapse development independent of its intracellular domain. J Neurosci. 2014;34:4187-99 pubmed publisher
Nieland T, Logan D, Saulnier J, Lam D, Johnson C, Root D, et al. High content image analysis identifies novel regulators of synaptogenesis in a high-throughput RNAi screen of primary neurons. PLoS ONE. 2014;9:e91744 pubmed publisher
del Pino I, Koch D, Schemm R, Qualmann B, Betz H, Paarmann I. Proteomic analysis of glycine receptor ? subunit (GlyR?)-interacting proteins: evidence for syndapin I regulating synaptic glycine receptors. J Biol Chem. 2014;289:11396-409 pubmed publisher
King A, Manning C, Trimmer J. A unique ion channel clustering domain on the axon initial segment of mammalian neurons. J Comp Neurol. 2014;522:2594-608 pubmed publisher
Pribiag H, Stellwagen D. TNF-? downregulates inhibitory neurotransmission through protein phosphatase 1-dependent trafficking of GABA(A) receptors. J Neurosci. 2013;33:15879-93 pubmed publisher
Ganser L, Yan Q, James V, Kozol R, Topf M, Harvey R, et al. Distinct phenotypes in zebrafish models of human startle disease. Neurobiol Dis. 2013;60:139-51 pubmed publisher
Bleckert A, Parker E, Kang Y, Pancaroglu R, Soto F, Lewis R, et al. Spatial relationships between GABAergic and glutamatergic synapses on the dendrites of distinct types of mouse retinal ganglion cells across development. PLoS ONE. 2013;8:e69612 pubmed publisher
Specht C, Izeddin I, Rodriguez P, El Beheiry M, Rostaing P, Darzacq X, et al. Quantitative nanoscopy of inhibitory synapses: counting gephyrin molecules and receptor binding sites. Neuron. 2013;79:308-21 pubmed publisher
Hennekinne L, Colasse S, Triller A, Renner M. Differential control of thrombospondin over synaptic glycine and AMPA receptors in spinal cord neurons. J Neurosci. 2013;33:11432-9 pubmed publisher
Tyagarajan S, Ghosh H, Yevenes G, Imanishi S, Zeilhofer H, Gerrits B, et al. Extracellular signal-regulated kinase and glycogen synthase kinase 3? regulate gephyrin postsynaptic aggregation and GABAergic synaptic function in a calpain-dependent mechanism. J Biol Chem. 2013;288:9634-47 pubmed publisher
Pettem K, Yokomaku D, Takahashi H, Ge Y, Craig A. Interaction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse development. J Cell Biol. 2013;200:321-36 pubmed publisher
Hughes D, Boyle K, Kinnon C, Bilsland C, Quayle J, Callister R, et al. HCN4 subunit expression in fast-spiking interneurons of the rat spinal cord and hippocampus. Neuroscience. 2013;237:7-18 pubmed publisher
Hruskova B, Trojanova J, Kulik A, Kralikova M, Pysanenko K, Bures Z, et al. Differential distribution of glycine receptor subtypes at the rat calyx of Held synapse. J Neurosci. 2012;32:17012-24 pubmed publisher
Garcia I, Huang L, Ung K, Arenkiel B. Tracing synaptic connectivity onto embryonic stem cell-derived neurons. Stem Cells. 2012;30:2140-51 pubmed publisher
Toossi H, Del Cid Pellitero E, Stroh T, Jones B. Somatostatin varicosities contain the vesicular GABA transporter and contact orexin neurons in the hypothalamus. Eur J Neurosci. 2012;36:3388-95 pubmed publisher
Körber C, Richter A, Kaiser M, Schlicksupp A, Mükusch S, Kuner T, et al. Effects of distinct collybistin isoforms on the formation of GABAergic synapses in hippocampal neurons. Mol Cell Neurosci. 2012;50:250-9 pubmed publisher
Li Z, Ge S, Zhang F, Zhang T, Mizuno N, Hioki H, et al. Distribution of gephyrin-immunoreactivity in the trigeminal motor nucleus: an immunohistochemical study in rats. Anat Rec (Hoboken). 2012;295:641-51 pubmed publisher
Hildebrandt H, Hoffmann N, Illing R. Synaptic reorganization in the adult rat's ventral cochlear nucleus following its total sensory deafferentation. PLoS ONE. 2011;6:e23686 pubmed publisher
Tretter V, Kerschner B, Milenkovic I, Ramsden S, Ramerstorfer J, Saiepour L, et al. Molecular basis of the γ-aminobutyric acid A receptor α3 subunit interaction with the clustering protein gephyrin. J Biol Chem. 2011;286:37702-11 pubmed publisher
Soto F, Bleckert A, Lewis R, Kang Y, Kerschensteiner D, Craig A, et al. Coordinated increase in inhibitory and excitatory synapses onto retinal ganglion cells during development. Neural Dev. 2011;6:31 pubmed publisher
Panzanelli P, Gunn B, Schlatter M, Benke D, Tyagarajan S, Scheiffele P, et al. Distinct mechanisms regulate GABAA receptor and gephyrin clustering at perisomatic and axo-axonic synapses on CA1 pyramidal cells. J Physiol. 2011;589:4959-80 pubmed publisher
Sardella T, Polgár E, Watanabe M, Todd A. A quantitative study of neuronal nitric oxide synthase expression in laminae I-III of the rat spinal dorsal horn. Neuroscience. 2011;192:708-20 pubmed publisher
Polgár E, Sardella T, Watanabe M, Todd A. Quantitative study of NPY-expressing GABAergic neurons and axons in rat spinal dorsal horn. J Comp Neurol. 2011;519:1007-23 pubmed publisher
Förstera B, Belaidi A, Jüttner R, Bernert C, Tsokos M, Lehmann T, et al. Irregular RNA splicing curtails postsynaptic gephyrin in the cornu ammonis of patients with epilepsy. Brain. 2010;133:3778-94 pubmed publisher
Dufour A, Tell F, Kessler J, Baude A. Mixed GABA-glycine synapses delineate a specific topography in the nucleus tractus solitarii of adult rat. J Physiol. 2010;588:1097-115 pubmed publisher
Suh Y, Terashima A, Petralia R, Wenthold R, Isaac J, Roche K, et al. A neuronal role for SNAP-23 in postsynaptic glutamate receptor trafficking. Nat Neurosci. 2010;13:338-43 pubmed publisher
Hughes E, Elmariah S, Balice Gordon R. Astrocyte secreted proteins selectively increase hippocampal GABAergic axon length, branching, and synaptogenesis. Mol Cell Neurosci. 2010;43:136-45 pubmed publisher
Belichenko P, Kleschevnikov A, Masliah E, Wu C, Takimoto Kimura R, Salehi A, et al. Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of Down syndrome. J Comp Neurol. 2009;512:453-66 pubmed publisher
Peden D, Petitjean C, Herd M, Durakoglugil M, Rosahl T, Wafford K, et al. Developmental maturation of synaptic and extrasynaptic GABAA receptors in mouse thalamic ventrobasal neurones. J Physiol. 2008;586:965-87 pubmed
Kang Y, Zhang X, Dobie F, Wu H, Craig A. Induction of GABAergic postsynaptic differentiation by alpha-neurexins. J Biol Chem. 2008;283:2323-34 pubmed
Aloy E, Weinmann O, Pot C, Kasper H, Dodd D, Rülicke T, et al. Synaptic destabilization by neuronal Nogo-A. Brain Cell Biol. 2006;35:137-56 pubmed
Tabuchi K, Blundell J, Etherton M, Hammer R, Liu X, Powell C, et al. A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice. Science. 2007;318:71-6 pubmed
Schneider Gasser E, Straub C, Panzanelli P, Weinmann O, Sassoè Pognetto M, Fritschy J. Immunofluorescence in brain sections: simultaneous detection of presynaptic and postsynaptic proteins in identified neurons. Nat Protoc. 2006;1:1887-97 pubmed
Graf E, Kang Y, Hauner A, Craig A. Structure function and splice site analysis of the synaptogenic activity of the neurexin-1 beta LNS domain. J Neurosci. 2006;26:4256-65 pubmed
Hartman K, Pal S, Burrone J, Murthy V. Activity-dependent regulation of inhibitory synaptic transmission in hippocampal neurons. Nat Neurosci. 2006;9:642-9 pubmed
Grady R, Wozniak D, Ohlemiller K, Sanes J. Cerebellar synaptic defects and abnormal motor behavior in mice lacking alpha- and beta-dystrobrevin. J Neurosci. 2006;26:2841-51 pubmed
Kralic J, Sidler C, Parpan F, Homanics G, Morrow A, Fritschy J. Compensatory alteration of inhibitory synaptic circuits in cerebellum and thalamus of gamma-aminobutyric acid type A receptor alpha1 subunit knockout mice. J Comp Neurol. 2006;495:408-21 pubmed
Maas C, Tagnaouti N, Loebrich S, Behrend B, Lappe Siefke C, Kneussel M. Neuronal cotransport of glycine receptor and the scaffold protein gephyrin. J Cell Biol. 2006;172:441-51 pubmed
Jacob T, Bogdanov Y, Magnus C, Saliba R, Kittler J, Haydon P, et al. Gephyrin regulates the cell surface dynamics of synaptic GABAA receptors. J Neurosci. 2005;25:10469-78 pubmed
Meier J, Grantyn R. A gephyrin-related mechanism restraining glycine receptor anchoring at GABAergic synapses. J Neurosci. 2004;24:1398-405 pubmed
Yazulla S, Studholme K. Neurochemical anatomy of the zebrafish retina as determined by immunocytochemistry. J Neurocytol. 2001;30:551-92 pubmed
Oleskevich S, Alvarez F, Walmsley B. Glycinergic miniature synaptic currents and receptor cluster sizes differ between spinal cord interneurons. J Neurophysiol. 1999;82:312-9 pubmed
product information
Cat. Nr. :
147 011
Antigen :
Gephyrin
Synonyms :
Gphn
Host Species :
mouse
Tpye :
monoclonal
Form :
purified IgG
Cell Line :
mAb7a
Subtype :
IgG1
Immunogen :
Native Protein corresponding to AA 1 to 768 from rat Gephyrin (UniProt Id: Q03555)
Reactivity :
human, rat, mouse, pig, goldfish, zebrafish, chicken
ICC :
ICC
IHC :
IHC
EM :
EM
KO :
yes
Quantity :
100 µg
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany