product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
Glycine receptor
catalog :
146 011
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
mAb4a
reactivity :
human, mouse, rat, zebrafish
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:500; loading ...; fig 2a
Schaefer N, Berger A, van Brederode J, Zheng F, Zhang Y, Leacock S, et al. Disruption of a Structurally Important Extracellular Element in the Glycine Receptor Leads to Decreased Synaptic Integration and Signaling Resulting in Severe Startle Disease. J Neurosci. 2017;37:7948-7961 pubmed publisher
  • immunocytochemistry; human; 1:500; loading ...; fig 5a
  • western blot; human; loading ...; fig 6a
Langlhofer G, Villmann C. The role of charged residues in independent glycine receptor folding domains for intermolecular interactions and ion channel function. J Neurochem. 2017;142:41-55 pubmed publisher
  • western blot; rat; 1:1000; fig 2h
Nakahata Y, Eto K, Murakoshi H, Watanabe M, Kuriu T, Hirata H, et al. Activation-Dependent Rapid Postsynaptic Clustering of Glycine Receptors in Mature Spinal Cord Neurons. Eneuro. 2017;4: pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1a
  • immunohistochemistry; mouse
Dlugaiczyk J, Hecker D, Neubert C, Buerbank S, Campanelli D, Becker C, et al. Loss of glycine receptors containing the α3 subunit compromises auditory nerve activity, but not outer hair cell function. Hear Res. 2016;337:25-34 pubmed publisher
Ganser L, Yan Q, James V, Kozol R, Topf M, Harvey R, et al. Distinct phenotypes in zebrafish models of human startle disease. Neurobiol Dis. 2013;60:139-51 pubmed publisher
Maas C, Tagnaouti N, Loebrich S, Behrend B, Lappe Siefke C, Kneussel M. Neuronal cotransport of glycine receptor and the scaffold protein gephyrin. J Cell Biol. 2006;172:441-51 pubmed
product information
Cat. Nr. :
146 011
Antigen :
Glycine receptor
Synonyms :
GlyR, Gly-R
Host Species :
mouse
Tpye :
monoclonal
Form :
purified IgG
Cell Line :
mAb4a
Subtype :
IgG1
Immunogen :
Recombinant protein corresponding to AA 1 to 457 from rat Glycine receptor alpha1 (UniProt Id: P07727)
Reactivity :
human, rat, mouse, pig, zebrafish
WB :
y
IP :
y
ICC :
y
IHC :
y
IHC P :
y
ELISA :
y
Quantity :
100 µg
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
www.sysy.com
49-551-50556-0
headquarters: germany