product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
VGLUT1
catalog :
135 304
quantity :
100 µl
clonality :
polyclonal
host :
guinea-pigs
conjugate :
nonconjugated
clone name :
/
reactivity :
mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, FACS, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
more info or order :
citations: 88
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:5000; loading ...; fig 3d1
McCabe M, Cullen E, Barrows C, Shore A, Tooke K, Laprade K, et al. Genetic inactivation of mTORC1 or mTORC2 in neurons reveals distinct functions in glutamatergic synaptic transmission. elife. 2020;9: pubmed publisher
  • immunohistochemistry - free floating section; rat; 1:500; loading ...; fig 7k
Linker K, Elabd M, Tawadrous P, Cano M, Green K, Wood M, et al. Microglial activation increases cocaine self-administration following adolescent nicotine exposure. Nat Commun. 2020;11:306 pubmed publisher
  • immunohistochemistry; mouse; 1:600; loading ...; fig 4a
Dorgans K, Demais V, Bailly Y, Poulain B, Isope P, Doussau F. Short-term plasticity at cerebellar granule cell to molecular layer interneuron synapses expands information processing. elife. 2019;8: pubmed publisher
  • immunohistochemistry; mouse; 1:4000; loading ...; fig f7s1a
Quade B, Camacho M, Zhao X, Orlando M, Trimbuch T, Xu J, et al. Membrane bridging by Munc13-1 is crucial for neurotransmitter release. elife. 2019;8: pubmed publisher
  • immunohistochemistry; mouse; 1:2000; loading ...; fig 7c
Shepard A, Scheffel J, Yu W. Relationships between neuronal birthdates and tonotopic positions in the mouse cochlear nucleus. J Comp Neurol. 2019;527:999-1011 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig ev2f
Fossati G, Pozzi D, Canzi A, Mirabella F, Valentino S, Morini R, et al. Pentraxin 3 regulates synaptic function by inducing AMPA receptor clustering via ECM remodeling and β1-integrin. EMBO J. 2019;38: pubmed publisher
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 2a
Muller T, Braud S, Jüttner R, Voigt B, Paulick K, Sheean M, et al. Neuregulin 3 promotes excitatory synapse formation on hippocampal interneurons. EMBO J. 2018;37: pubmed publisher
  • immunohistochemistry; mouse; fig s7c
Liu C, Kershberg L, Wang J, Schneeberger S, Kaeser P. Dopamine Secretion Is Mediated by Sparse Active Zone-like Release Sites. Cell. 2018;172:706-718.e15 pubmed publisher
  • western blot; mouse; loading ...; fig 1a
Richter K, Schmutz I, Darna M, Zander J, Chavan R, Albrecht U, et al. VGLUT1 Binding to Endophilin or Intersectin1 and Dynamin Phosphorylation in a Diurnal Context. Neuroscience. 2018;371:29-37 pubmed publisher
  • immunocytochemistry; mouse; 1:400; loading ...; fig 7b
Zhao Y, Tian J, Sui S, Yuan X, Chen H, Qu C, et al. Loss of succinyl-CoA synthase ADP-forming β subunit disrupts mtDNA stability and mitochondrial dynamics in neurons. Sci Rep. 2017;7:7169 pubmed publisher
  • immunocytochemistry; mouse; 1:4000; loading ...; fig s5a
Redmond S, Mei F, Eshed Eisenbach Y, Osso L, Leshkowitz D, Shen Y, et al. Somatodendritic Expression of JAM2 Inhibits Oligodendrocyte Myelination. Neuron. 2016;91:824-836 pubmed publisher
  • immunocytochemistry; mouse; 1:2000; fig 7
Schmitt D, Funk N, Blum R, Asan E, Andersen L, Rülicke T, et al. Initial characterization of a Syap1 knock-out mouse and distribution of Syap1 in mouse brain and cultured motoneurons. Histochem Cell Biol. 2016;146:489-512 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:300; fig s3
Vasek M, Garber C, Dorsey D, Durrant D, Bollman B, Soung A, et al. A complement-microglial axis drives synapse loss during virus-induced memory impairment. Nature. 2016;534:538-43 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; fig s4
Heise C, Schroeder J, Schoen M, Halbedl S, Reim D, Woelfle S, et al. Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus. Front Cell Neurosci. 2016;10:106 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig s1A-1
He J, Zhou R, Wu Z, Carrasco M, Kurshan P, Farley J, et al. Prevalent presence of periodic actin-spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species. Proc Natl Acad Sci U S A. 2016;113:6029-34 pubmed publisher
  • immunocytochemistry; mouse; 1:400; fig 3
Beck S, Guo L, Phensy A, Tian J, Wang L, Tandon N, et al. Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer's disease. Nat Commun. 2016;7:11483 pubmed publisher
  • immunohistochemistry; mouse; 1:500; fig s2
Jackman S, Turecek J, Belinsky J, Regehr W. The calcium sensor synaptotagmin 7 is required for synaptic facilitation. Nature. 2016;529:88-91 pubmed publisher
  • immunocytochemistry; rat; fig 2
Tagliatti E, Fadda M, Falace A, Benfenati F, Fassio A. Arf6 regulates the cycling and the readily releasable pool of synaptic vesicles at hippocampal synapse. elife. 2016;5: pubmed publisher
Deng S, Li J, He Q, Zhang X, Zhu J, Li L, et al. Regulation of Recurrent Inhibition by Asynchronous Glutamate Release in Neocortex. Neuron. 2019;: pubmed publisher
Sun W, Larson M, Kiyoshi C, Annett A, Stalker W, Peng J, et al. Gabapentinoid treatment promotes corticospinal plasticity and regeneration following murine spinal cord injury. J Clin Invest. 2019;: pubmed publisher
Esposito A, Falace A, Wagner M, Gal M, Mei D, Conti V, et al. Biallelic DMXL2 mutations impair autophagy and cause Ohtahara syndrome with progressive course. Brain. 2019;142:3876-3891 pubmed publisher
Handara G, Kroger S. Alternative Splicing and the Intracellular Domain Mediate TM-agrin's Ability to Differentially Regulate the Density of Excitatory and Inhibitory Synapse-like Specializations in Developing CNS Neurons. Neuroscience. 2019;419:60-71 pubmed publisher
Itoh K, Murata D, Kato T, Yamada T, Araki Y, Saito A, et al. Brain-specific Drp1 regulates postsynaptic endocytosis and dendrite formation independently of mitochondrial division. elife. 2019;8: pubmed publisher
Gottschling C, Wegrzyn D, Denecke B, Faissner A. Elimination of the four extracellular matrix molecules tenascin-C, tenascin-R, brevican and neurocan alters the ratio of excitatory and inhibitory synapses. Sci Rep. 2019;9:13939 pubmed publisher
Ge Y, Tian M, Liu L, Wong T, Gong B, Wu D, et al. p97 regulates GluA1 homomeric AMPA receptor formation and plasma membrane expression. Nat Commun. 2019;10:4089 pubmed publisher
Yang Q, Huang Z, Luo Y, Zheng F, Hu Y, Liu H, et al. Inhibition of Nwd1 activity attenuates neuronal hyperexcitability and GluN2B phosphorylation in the hippocampus. EBioMedicine. 2019;47:470-483 pubmed publisher
Kono R, Kim G, Nagata H, Ikegaya Y, Koyama R. Induced neuronal activity does not attenuate amyloid beta-induced synaptic loss in vitro. Neuropsychopharmacol Rep. 2019;: pubmed publisher
Lin S, Xie R. Principal Neurons in the Anteroventral Cochlear Nucleus Express Cell-Type Specific Glycine Receptor α Subunits. Neuroscience. 2019;415:77-88 pubmed publisher
Rajaram E, Kaltenbach C, Fischl M, Mrowka L, Alexandrova O, Grothe B, et al. Slow NMDA-Mediated Excitation Accelerates Offset-Response Latencies Generated via a Post-Inhibitory Rebound Mechanism. Eneuro. 2019;6: pubmed publisher
Hobson B, Sims P. Critical Analysis of Particle Detection Artifacts in Synaptosome Flow Cytometry. Eneuro. 2019;6: pubmed publisher
Hwang S, Kim J, Kim S. Heterogeneity of GRIM-19 Expression in the Adult Mouse Brain. Cell Mol Neurobiol. 2019;: pubmed publisher
Pfeiffer F, Frommer Kaestle G, Fallier Becker P. Structural adaption of axons during de- and remyelination in the Cuprizone mouse model. Brain Pathol. 2019;: pubmed publisher
Ackermann F, Schink K, Bruns C, Izsvák Z, Hamra F, Rosenmund C, et al. Critical role for Piccolo in synaptic vesicle retrieval. elife. 2019;8: pubmed publisher
Pernice H, Schieweck R, Jafari M, Straub T, Bilban M, Kiebler M, et al. Altered Glutamate Receptor Ionotropic Delta Subunit 2 Expression in Stau2-Deficient Cerebellar Purkinje Cells in the Adult Brain. Int J Mol Sci. 2019;20: pubmed publisher
Paraskevopoulou F, Herman M, Rosenmund C. Glutamatergic Innervation onto Striatal Neurons Potentiates GABAergic Synaptic Output. J Neurosci. 2019;39:4448-4460 pubmed publisher
Naskar S, Narducci R, Balzani E, Cwetsch A, Tucci V, Cancedda L. The development of synaptic transmission is time-locked to early social behaviors in rats. Nat Commun. 2019;10:1195 pubmed publisher
WADHWANI A, Affaneh A, Van Gulden S, Kessler J. Neuronal apolipoprotein E4 increases cell death and phosphorylated tau release in alzheimer disease. Ann Neurol. 2019;85:726-739 pubmed publisher
Rotterman T, Akhter E, Lane A, Macpherson K, Garcia V, TANSEY M, et al. Spinal Motor Circuit Synaptic Plasticity after Peripheral Nerve Injury Depends on Microglia Activation and a CCR2 Mechanism. J Neurosci. 2019;39:3412-3433 pubmed publisher
Davenport E, Szulc B, Drew J, Taylor J, Morgan T, Higgs N, et al. Autism and Schizophrenia-Associated CYFIP1 Regulates the Balance of Synaptic Excitation and Inhibition. Cell Rep. 2019;26:2037-2051.e6 pubmed publisher
Larsson M, Broman J. Synaptic Organization of VGLUT3 Expressing Low-Threshold Mechanosensitive C Fiber Terminals in the Rodent Spinal Cord. Eneuro. 2019;6: pubmed publisher
Ruiz Reig N, Rakotobe M, Bethus I, Le Menn G, Huditz H, Marie H, et al. Developmental Requirement of Homeoprotein Otx2 for Specific Habenulo-Interpeduncular Subcircuits. J Neurosci. 2019;39:1005-1019 pubmed publisher
Kubo A, Misonou H, Matsuyama M, Nomori A, Wada Kakuda S, Takashima A, et al. Distribution of endogenous normal tau in the mouse brain. J Comp Neurol. 2019;527:985-998 pubmed publisher
Handara G, Hetsch F, Jüttner R, Schick A, Haupt C, Rathjen F, et al. The role of agrin, Lrp4 and MuSK during dendritic arborization and synaptogenesis in cultured embryonic CNS neurons. Dev Biol. 2019;445:54-67 pubmed publisher
Medrano Fernandez A, Delgado Garcia J, Del Blanco B, Llinares M, Sánchez Campusano R, Olivares R, et al. The Epigenetic Factor CBP Is Required for the Differentiation and Function of Medial Ganglionic Eminence-Derived Interneurons. Mol Neurobiol. 2019;56:4440-4454 pubmed publisher
Valente P, Romei A, Fadda M, Sterlini B, Lonardoni D, Forte N, et al. Constitutive Inactivation of the PRRT2 Gene Alters Short-Term Synaptic Plasticity and Promotes Network Hyperexcitability in Hippocampal Neurons. Cereb Cortex. 2019;29:2010-2033 pubmed publisher
Herman M, Trimbuch T, Rosenmund C. Differential pH Dynamics in Synaptic Vesicles From Intact Glutamatergic and GABAergic Synapses. Front Synaptic Neurosci. 2018;10:44 pubmed publisher
Wouterlood F, van Oort S, Bloemhard L, Flierman N, Spijkerman J, Wright C, et al. Neurochemical fingerprinting of amygdalostriatal and intra-amygdaloid projections: a tracing-immunofluorescence study in the rat. J Chem Neuroanat. 2018;94:154-172 pubmed publisher
Scarnati M, Kataria R, Biswas M, Paradiso K. Active presynaptic ribosomes in the mammalian brain, and altered transmitter release after protein synthesis inhibition. elife. 2018;7: pubmed publisher
Edamatsu M, Miyano R, Fujikawa A, Fujii F, Hori T, Sakaba T, et al. Hapln4/Bral2 is a selective regulator for formation and transmission of GABAergic synapses between Purkinje and deep cerebellar nuclei neurons. J Neurochem. 2018;147:748-763 pubmed publisher
Carter B, Sullivan B, Landers J, Kadam S. Dose-dependent reversal of KCC2 hypofunction and phenobarbital-resistant neonatal seizures by ANA12. Sci Rep. 2018;8:11987 pubmed publisher
Wang F, Yang Y, Yang N, Chen X, Huang N, Zhang J, et al. Enhancing Oligodendrocyte Myelination Rescues Synaptic Loss and Improves Functional Recovery after Chronic Hypoxia. Neuron. 2018;99:689-701.e5 pubmed publisher
Wallrafen R, Dresbach T. The Presynaptic Protein Mover Is Differentially Expressed Across Brain Areas and Synapse Types. Front Neuroanat. 2018;12:58 pubmed publisher
Yang Q, Zheng F, Hu Y, Yang Y, Li Y, Chen G, et al. ZDHHC8 critically regulates seizure susceptibility in epilepsy. Cell Death Dis. 2018;9:795 pubmed publisher
Dong W, Radulović T, Goral R, Thomas C, Suarez Montesinos M, Guerrero Given D, et al. CAST/ELKS Proteins Control Voltage-Gated Ca2+ Channel Density and Synaptic Release Probability at a Mammalian Central Synapse. Cell Rep. 2018;24:284-293.e6 pubmed publisher
Hayani H, Song I, Dityatev A. Increased Excitability and Reduced Excitatory Synaptic Input Into Fast-Spiking CA2 Interneurons After Enzymatic Attenuation of Extracellular Matrix. Front Cell Neurosci. 2018;12:149 pubmed publisher
Silva A, Lemos C, Gonçalves F, Pliássova A, Machado N, Silva H, et al. Blockade of adenosine A2A receptors recovers early deficits of memory and plasticity in the triple transgenic mouse model of Alzheimer's disease. Neurobiol Dis. 2018;117:72-81 pubmed publisher
Cerveró C, Blasco A, Tarabal O, Casanovas A, Piedrafita L, Navarro X, et al. Glial Activation and Central Synapse Loss, but Not Motoneuron Degeneration, Are Prevented by the Sigma-1 Receptor Agonist PRE-084 in the Smn2B/- Mouse Model of Spinal Muscular Atrophy. J Neuropathol Exp Neurol. 2018;77:577-597 pubmed publisher
Filipello F, Morini R, Corradini I, Zerbi V, Canzi A, Michalski B, et al. The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity. Immunity. 2018;48:979-991.e8 pubmed publisher
Kim Y, Kim S, Lee J, Ko S, Bae Y. Expression of vesicular glutamate transporters in transient receptor potential ankyrin 1 (TRPA1)-positive neurons in the rat trigeminal ganglion. Brain Res. 2018;1690:31-39 pubmed publisher
Turecek J, Regehr W. Synaptotagmin 7 Mediates Both Facilitation and Asynchronous Release at Granule Cell Synapses. J Neurosci. 2018;38:3240-3251 pubmed publisher
He Y, Jia K, Li L, Wang Q, Zhang S, Du J, et al. Salvianolic acid B attenuates mitochondrial stress against Aβ toxicity in primary cultured mouse neurons. Biochem Biophys Res Commun. 2018;498:1066-1072 pubmed publisher
Guo N, Soden M, Herber C, Kim M, Besnard A, Lin P, et al. Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization. Nat Med. 2018;24:438-449 pubmed publisher
Park S, Ko S, Paik S, Rah J, Lee K, Bae Y. Vesicular glutamate transporter 1 (VGLUT1)- and VGLUT2-immunopositive axon terminals on the rat jaw-closing and jaw-opening motoneurons. Brain Struct Funct. 2018;223:2323-2334 pubmed publisher
Simões A, Silva C, Marques J, Pochmann D, Porciúncula L, Ferreira S, et al. Glutamate-induced and NMDA receptor-mediated neurodegeneration entails P2Y1 receptor activation. Cell Death Dis. 2018;9:297 pubmed publisher
Wang Y, Ji T, Nelson A, Glanowska K, Murphy G, Jenkins P, et al. Critical roles of αII spectrin in brain development and epileptic encephalopathy. J Clin Invest. 2018;128:760-773 pubmed publisher
Hoshino A, Ratnapriya R, Brooks M, Chaitankar V, Wilken M, Zhang C, et al. Molecular Anatomy of the Developing Human Retina. Dev Cell. 2017;43:763-779.e4 pubmed publisher
Li P, Fu X, Smith N, Ziobro J, Curiel J, Tenga M, et al. Loss of CLOCK Results in Dysfunction of Brain Circuits Underlying Focal Epilepsy. Neuron. 2017;96:387-401.e6 pubmed publisher
Dzyubenko E, Juckel G, Faissner A. The antipsychotic drugs olanzapine and haloperidol modify network connectivity and spontaneous activity of neural networks in vitro. Sci Rep. 2017;7:11609 pubmed publisher
Chu H, McIver E, Kovaleski R, Atherton J, Bevan M. Loss of Hyperdirect Pathway Cortico-Subthalamic Inputs Following Degeneration of Midbrain Dopamine Neurons. Neuron. 2017;95:1306-1318.e5 pubmed publisher
Liu Y, Wang X, Li W, Zhang Q, Li Y, Zhang Z, et al. A Sensitized IGF1 Treatment Restores Corticospinal Axon-Dependent Functions. Neuron. 2017;95:817-833.e4 pubmed publisher
Vincent J, Gabriel H, Deardorff A, Nardelli P, Fyffe R, BURKHOLDER T, et al. Muscle proprioceptors in adult rat: mechanosensory signaling and synapse distribution in spinal cord. J Neurophysiol. 2017;118:2687-2701 pubmed publisher
Stein L, Zorumski C, Izumi Y. Hippocampal slice preparation in rats acutely suppresses immunoreactivity of microtubule-associated protein (Map2) and glycogen levels without affecting numbers of glia or levels of the glutamate transporter VGlut1. Brain Behav. 2017;7:e00736 pubmed publisher
Tomasoni R, Morini R, Lopez Atalaya J, Corradini I, Canzi A, Rasile M, et al. Lack of IL-1R8 in neurons causes hyperactivation of IL-1 receptor pathway and induces MECP2-dependent synaptic defects. elife. 2017;6: pubmed publisher
Chiacchiaretta M, Latifi S, Bramini M, Fadda M, Fassio A, Benfenati F, et al. Neuronal hyperactivity causes Na+/H+ exchanger-induced extracellular acidification at active synapses. J Cell Sci. 2017;130:1435-1449 pubmed publisher
Casanovas A, Salvany S, Lahoz V, Tarabal O, Piedrafita L, Sabater R, et al. Neuregulin 1-ErbB module in C-bouton synapses on somatic motor neurons: molecular compartmentation and response to peripheral nerve injury. Sci Rep. 2017;7:40155 pubmed publisher
Hayano Y, Takasu K, Koyama Y, Yamada M, Ogawa K, Minami K, et al. Dorsal horn interneuron-derived Netrin-4 contributes to spinal sensitization in chronic pain via Unc5B. J Exp Med. 2016;213:2949-2966 pubmed
Bott J, Héraud C, Cosquer B, Herbeaux K, Aubert J, Sartori M, et al. APOE-Sensitive Cholinergic Sprouting Compensates for Hippocampal Dysfunctions Due to Reduced Entorhinal Input. J Neurosci. 2016;36:10472-10486 pubmed
Früh S, Romanos J, Panzanelli P, Bürgisser D, Tyagarajan S, Campbell K, et al. Neuronal Dystroglycan Is Necessary for Formation and Maintenance of Functional CCK-Positive Basket Cell Terminals on Pyramidal Cells. J Neurosci. 2016;36:10296-10313 pubmed
Fischl M, Burger R, Schmidt Pauly M, Alexandrova O, Sinclair J, Grothe B, et al. Physiology and anatomy of neurons in the medial superior olive of the mouse. J Neurophysiol. 2016;116:2676-2688 pubmed publisher
Wei H, Ma Y, Ding C, Jin G, Liu J, Chang Q, et al. Reduced Glutamate Release in Adult BTBR Mouse Model of Autism Spectrum Disorder. Neurochem Res. 2016;41:3129-3137 pubmed
Bagga P, Crescenzi R, Krishnamoorthy G, Verma G, Nanga R, Reddy D, et al. Mapping the alterations in glutamate with GluCEST MRI in a mouse model of dopamine deficiency. J Neurochem. 2016;139:432-439 pubmed publisher
Wei H, Ma Y, Liu J, Ding C, Jin G, Wang Y, et al. Inhibition of IL-6 trans-signaling in the brain increases sociability in the BTBR mouse model of autism. Biochim Biophys Acta. 2016;1862:1918-25 pubmed publisher
Gödde K, Gschwend O, Puchkov D, Pfeffer C, Carleton A, Jentsch T. Disruption of Kcc2-dependent inhibition of olfactory bulb output neurons suggests its importance in odour discrimination. Nat Commun. 2016;7:12043 pubmed publisher
Etxeberria A, Hokanson K, Dao D, Mayoral S, Mei F, Redmond S, et al. Dynamic Modulation of Myelination in Response to Visual Stimuli Alters Optic Nerve Conduction Velocity. J Neurosci. 2016;36:6937-48 pubmed publisher
Held R, Liu C, Kaeser P. ELKS controls the pool of readily releasable vesicles at excitatory synapses through its N-terminal coiled-coil domains. elife. 2016;5: pubmed publisher
Amin H, Maccione A, Marinaro F, Zordan S, Nieus T, Berdondini L. Electrical Responses and Spontaneous Activity of Human iPS-Derived Neuronal Networks Characterized for 3-month Culture with 4096-Electrode Arrays. Front Neurosci. 2016;10:121 pubmed publisher
Valente P, Castroflorio E, Rossi P, Fadda M, Sterlini B, Cervigni R, et al. PRRT2 Is a Key Component of the Ca(2+)-Dependent Neurotransmitter Release Machinery. Cell Rep. 2016;15:117-131 pubmed publisher
Takahashi D, Gu F, Parada I, Vyas S, Prince D. Aberrant excitatory rewiring of layer V pyramidal neurons early after neocortical trauma. Neurobiol Dis. 2016;91:166-81 pubmed publisher
product information
Cat. Nr. :
135 304
Antigen :
VGLUT1
Synonyms :
BNPI, SLC17A7, VGLUT 1
Host Species :
Guinea pig
Tpye :
polyclonal
Form :
antiserum
Immunogen :
Recombinant protein corresponding to AA 456 to 560 from rat VGLUT1 (UniProt Id: Q62634)
Reactivity :
rat, mouse, human, cow
WB :
WB
IP :
IP
ICC :
ICC
IHC :
IHC
IHC P :
IHC-P
EM :
EM
FACS :
FACS
KO :
yes
Quantity :
100 µl
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany