product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
VGLUT1
catalog :
135 303
quantity :
50 µg
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section, immunohistochemistry - frozen section, immunohistochemistry - free floating section
more info or order :
citations: 79
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:1000; loading ...
Ishii C, Shibano N, Yamazaki M, Arima T, Kato Y, Ishii Y, et al. CAPS1 is involved in hippocampal synaptic plasticity and hippocampus-associated learning. Sci Rep. 2021;11:8656 pubmed publisher
  • western blot; human; loading ...; fig 2a
Yao W, Tambini M, Liu X, D ADAMIO L. Tuning of glutamate, but not GABA, release by an intra-synaptic vesicles APP domain whose function can be modulated by β- or α-secretase cleavage. J Neurosci. 2019;: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:7500; loading ...; fig 2a
Hunter D, Manglapus M, Bachay G, Claudepierre T, Dolan M, Gesuelli K, et al. CNS synapses are stabilized trans-synaptically by laminins and laminin-interacting proteins. J Comp Neurol. 2017;: pubmed publisher
  • western blot; rat; 1:1000; loading ...; fig 5a
Wolfes A, Ahmed S, Awasthi A, Stahlberg M, Rajput A, Magruder D, et al. A novel method for culturing stellate astrocytes reveals spatially distinct Ca2+ signaling and vesicle recycling in astrocytic processes. J Gen Physiol. 2017;149:149-170 pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:500; fig 4
Alvarez Saavedra M, De Repentigny Y, Yang D, O Meara R, Yan K, Hashem L, et al. Voluntary Running Triggers VGF-Mediated Oligodendrogenesis to Prolong the Lifespan of Snf2h-Null Ataxic Mice. Cell Rep. 2016;17:862-875 pubmed publisher
  • immunocytochemistry; human; 1:1000; loading ...; tbl s4
Hansen S, Stummann T, Borland H, Hasholt L, Tumer Z, Nielsen J, et al. Induced pluripotent stem cell - derived neurons for the study of spinocerebellar ataxia type 3. Stem Cell Res. 2016;17:306-317 pubmed publisher
  • western blot; rat; fig 5
Yokoi N, Fukata Y, Sekiya A, Murakami T, Kobayashi K, Fukata M. Identification of PSD-95 Depalmitoylating Enzymes. J Neurosci. 2016;36:6431-44 pubmed publisher
  • immunocytochemistry; human; 1:200; fig 3
Xue Y, Qian H, Hu J, Zhou B, Zhou Y, Hu X, et al. Sequential regulatory loops as key gatekeepers for neuronal reprogramming in human cells. Nat Neurosci. 2016;19:807-15 pubmed publisher
  • immunocytochemistry; rat; 1:1000; loading ...; tbl 3
Bartelt Kirbach B, Moron M, Glomb M, Beck C, Weller M, Golenhofen N. HspB5/?B-crystallin increases dendritic complexity and protects the dendritic arbor during heat shock in cultured rat hippocampal neurons. Cell Mol Life Sci. 2016;73:3761-75 pubmed publisher
  • immunocytochemistry; human; fig s2
Kim E, Jeon C, Lee S, Hwang I, Chung T. Robust Type-specific Hemisynapses Induced by Artificial Dendrites. Sci Rep. 2016;6:24210 pubmed publisher
  • western blot; mouse; fig 2
Hayashi Y, Nishimune H, Hozumi K, Saga Y, Harada A, Yuzaki M, et al. A novel non-canonical Notch signaling regulates expression of synaptic vesicle proteins in excitatory neurons. Sci Rep. 2016;6:23969 pubmed publisher
Mukherjee A, Bajwa N, Lam N, Porrero C, Clascá F, Halassa M. Variation of connectivity across exemplar sensory and associative thalamocortical loops in the mouse. elife. 2020;9: pubmed publisher
Chantranupong L, Saulnier J, Wang W, Jones D, Pacold M, Sabatini B. Rapid purification and metabolomic profiling of synaptic vesicles from mammalian brain. elife. 2020;9: pubmed publisher
Maynard M, Redell J, Kobori N, Underwood E, Fischer T, Hood K, et al. Loss of PTEN-induced kinase 1 (Pink1) reduces hippocampal tyrosine hydroxylase and impairs learning and memory. Exp Neurol. 2020;323:113081 pubmed publisher
Ruiter M, Houy S, Engholm Keller K, Graham M, Sørensen J. SNAP-25 phosphorylation at Ser187 is not involved in Ca2+ or phorbolester-dependent potentiation of synaptic release. Mol Cell Neurosci. 2019;102:103452 pubmed publisher
Ghatak S, Dolatabadi N, Trudler D, Zhang X, Wu Y, Mohata M, et al. Mechanisms of hyperexcitability in Alzheimer's disease hiPSC-derived neurons and cerebral organoids vs isogenic controls. elife. 2019;8: pubmed publisher
Ribeiro P, Castro M, Perez M, Cartarozzi L, Spejo A, Chiarotto G, et al. Toll-like receptor 4 (TLR4) influences the glial reaction in the spinal cord and the neural response to injury following peripheral nerve crush. Brain Res Bull. 2019;155:67-80 pubmed publisher
Bashir A, Abebe Z, McInnes K, Button E, Tatarnikov I, Cheng W, et al. Increased severity of the CHIMERA model induces acute vascular injury, sub-acute deficits in memory recall, and chronic white matter gliosis. Exp Neurol. 2019;324:113116 pubmed publisher
Lindstrom S, Sundberg S, Larsson M, Andersson F, Broman J, Granseth B. VGluT1 Deficiency Impairs Visual Attention and Reduces the Dynamic Range of Short-Term Plasticity at Corticothalamic Synapses. Cereb Cortex. 2019;: pubmed publisher
Moretto E, Longatti A, Murru L, Chamma I, Sessa A, Zapata J, et al. TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering. Cell Rep. 2019;29:1130-1146.e8 pubmed publisher
Kim J, Lana B, Torelli S, Ryan D, Catapano F, Ala P, et al. A new patient-derived iPSC model for dystroglycanopathies validates a compound that increases glycosylation of α-dystroglycan. EMBO Rep. 2019;20:e47967 pubmed publisher
Różycka A, Charzynska A, Misiewicz Z, Maciej Stepniewski T, Sobolewska A, Kossut M, et al. Glutamate, GABA, and Presynaptic Markers Involved in Neurotransmission Are Differently Affected by Age in Distinct Mouse Brain Regions. ACS Chem Neurosci. 2019;10:4449-4461 pubmed publisher
Park H, Kim T, Kim J, Yamamoto Y, Tanaka Yamamoto K. Inputs from Sequentially Developed Parallel Fibers Are Required for Cerebellar Organization. Cell Rep. 2019;28:2939-2954.e5 pubmed publisher
Tambini M, Yao W, D ADAMIO L. Facilitation of glutamate, but not GABA, release in Familial Alzheimer's APP mutant Knock-in rats with increased β-cleavage of APP. Aging Cell. 2019;18:e13033 pubmed publisher
Tullii G, Giona F, Lodola F, Bonfadini S, Bossio C, Varo S, et al. High-Aspect-Ratio Semiconducting Polymer Pillars for 3D Cell Cultures. ACS Appl Mater Interfaces. 2019;11:28125-28137 pubmed publisher
Castro M, Silva M, Chiarotto G, Volpe B, Santana M, Malheiros Luzo A, et al. Reflex arc recovery after spinal cord dorsal root repair with platelet rich plasma (PRP). Brain Res Bull. 2019;152:212-224 pubmed publisher
Jurek B, Chayka M, Kreye J, Lang K, Kraus L, Fidzinski P, et al. Human gestational N-methyl-d-aspartate receptor autoantibodies impair neonatal murine brain function. Ann Neurol. 2019;: pubmed publisher
Sakaguchi H, Ozaki Y, Ashida T, Matsubara T, Oishi N, Kihara S, et al. Self-Organized Synchronous Calcium Transients in a Cultured Human Neural Network Derived from Cerebral Organoids. Stem Cell Reports. 2019;13:458-473 pubmed publisher
Adaikkan C, Middleton S, Marco A, Pao P, Mathys H, Kim D, et al. Gamma Entrainment Binds Higher-Order Brain Regions and Offers Neuroprotection. Neuron. 2019;102:929-943.e8 pubmed publisher
Rotterman T, Akhter E, Lane A, Macpherson K, Garcia V, TANSEY M, et al. Spinal Motor Circuit Synaptic Plasticity after Peripheral Nerve Injury Depends on Microglia Activation and a CCR2 Mechanism. J Neurosci. 2019;39:3412-3433 pubmed publisher
Pai E, Vogt D, Clemente Perez A, McKinsey G, Cho F, Hu J, et al. Mafb and c-Maf Have Prenatal Compensatory and Postnatal Antagonistic Roles in Cortical Interneuron Fate and Function. Cell Rep. 2019;26:1157-1173.e5 pubmed publisher
Park J, Longo F, Park S, Lee S, Bae M, Tyagi R, et al. Inositol polyphosphate multikinase mediates extinction of fear memory. Proc Natl Acad Sci U S A. 2019;116:2707-2712 pubmed publisher
Maynard M, Underwood E, Redell J, Zhao J, Kobori N, Hood K, et al. Carnosic Acid Improves Outcome after Repetitive Mild Traumatic Brain Injury. J Neurotrauma. 2019;: pubmed publisher
Spejo A, Teles C, Zuccoli G, Oliveira A. Synapse preservation and decreased glial reactions following ventral root crush (VRC) and treatment with 4-hydroxy-tempo (TEMPOL). J Neurosci Res. 2019;97:520-534 pubmed publisher
Awasthi A, Ramachandran B, Ahmed S, Benito E, Shinoda Y, Nitzan N, et al. Synaptotagmin-3 drives AMPA receptor endocytosis, depression of synapse strength, and forgetting. Science. 2019;363: pubmed publisher
Finelli M, Aprile D, Castroflorio E, Jeans A, Moschetta M, Chessum L, et al. The epilepsy-associated protein TBC1D24 is required for normal development, survival and vesicle trafficking in mammalian neurons. Hum Mol Genet. 2019;28:584-597 pubmed publisher
McKenzie C, Spanova M, Johnson A, Kainrath S, Zheden V, Sitte H, et al. Isolation of synaptic vesicles from genetically engineered cultured neurons. J Neurosci Methods. 2018;312:114-121 pubmed publisher
Ozek C, Krolewski R, Buchanan S, Rubin L. Growth Differentiation Factor 11 treatment leads to neuronal and vascular improvements in the hippocampus of aged mice. Sci Rep. 2018;8:17293 pubmed publisher
Srikanth P, Lagomarsino V, PEARSE R, Liao M, Ghosh S, Nehme R, et al. Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression. Transl Psychiatry. 2018;8:245 pubmed publisher
Irintchev M, Guntinas Lichius O, Irintchev A. Botulinum Neurotoxin Application to the Severed Femoral Nerve Modulates Spinal Synaptic Responses to Axotomy and Enhances Motor Recovery in Rats. Neural Plast. 2018;2018:7975013 pubmed publisher
Trobiani L, Favaloro F, Di Castro M, Di Mattia M, Cariello M, Miranda E, et al. UPR activation specifically modulates glutamate neurotransmission in the cerebellum of a mouse model of autism. Neurobiol Dis. 2018;120:139-150 pubmed publisher
Tu Y, Duman J, Tolias K. The Adhesion-GPCR BAI1 Promotes Excitatory Synaptogenesis by Coordinating Bidirectional Trans-synaptic Signaling. J Neurosci. 2018;38:8388-8406 pubmed publisher
Zhang P, Lu H, Peixoto R, Pines M, Ge Y, Oku S, et al. Heparan Sulfate Organizes Neuronal Synapses through Neurexin Partnerships. Cell. 2018;174:1450-1464.e23 pubmed publisher
Krishnan V, Shavlakadze T, Grounds M, Hodgetts S, Harvey A. Age-related loss of VGLUT1 excitatory, but not VGAT inhibitory, immunoreactive terminals on motor neurons in spinal cords of old sarcopenic male mice. Biogerontology. 2018;19:385-399 pubmed publisher
Sunamura N, Iwashita S, Enomoto K, Kadoshima T, Isono F. Loss of the fragile X mental retardation protein causes aberrant differentiation in human neural progenitor cells. Sci Rep. 2018;8:11585 pubmed publisher
Song J, Lucaci D, Calangiu I, Brown M, Park J, Kim J, et al. Combining mGRASP and Optogenetics Enables High-Resolution Functional Mapping of Descending Cortical Projections. Cell Rep. 2018;24:1071-1080 pubmed publisher
Cheadle L, Tzeng C, Kalish B, Harmin D, Rivera S, Ling E, et al. Visual Experience-Dependent Expression of Fn14 Is Required for Retinogeniculate Refinement. Neuron. 2018;99:525-539.e10 pubmed publisher
Jhang J, Lee H, Kang M, Lee H, Park H, Han J. Anterior cingulate cortex and its input to the basolateral amygdala control innate fear response. Nat Commun. 2018;9:2744 pubmed publisher
Grillo F, Neves G, Walker A, Vizcay Barrena G, Fleck R, Branco T, et al. A Distance-Dependent Distribution of Presynaptic Boutons Tunes Frequency-Dependent Dendritic Integration. Neuron. 2018;99:275-282.e3 pubmed publisher
Alexander N, Rau A, Jimenez V, Daunais J, Grant K, McCool B. SNARE Complex-Associated Proteins in the Lateral Amygdala of Macaca mulatta Following Long-Term Ethanol Drinking. Alcohol Clin Exp Res. 2018;42:1661-1673 pubmed publisher
Li Y, Kim R, Cho Y, Song W, Kim D, Kim K, et al. Lrfn2-Mutant Mice Display Suppressed Synaptic Plasticity and Inhibitory Synapse Development and Abnormal Social Communication and Startle Response. J Neurosci. 2018;38:5872-5887 pubmed publisher
Cabezas Llobet N, Vidal Sancho L, Masana M, Fournier A, Alberch J, Vaudry D, et al. Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) Enhances Hippocampal Synaptic Plasticity and Improves Memory Performance in Huntington's Disease. Mol Neurobiol. 2018;55:8263-8277 pubmed publisher
Myers B, McKlveen J, Morano R, Ulrich Lai Y, Solomon M, Wilson S, et al. Vesicular Glutamate Transporter 1 Knockdown in Infralimbic Prefrontal Cortex Augments Neuroendocrine Responses to Chronic Stress in Male Rats. Endocrinology. 2017;158:3579-3591 pubmed publisher
Roy D, Kitamura T, Okuyama T, Ogawa S, Sun C, Obata Y, et al. Distinct Neural Circuits for the Formation and Retrieval of Episodic Memories. Cell. 2017;170:1000-1012.e19 pubmed publisher
Sano N, Shimogawa T, Sakaguchi H, Ioroi Y, Miyawaki Y, Morizane A, et al. Enhanced Axonal Extension of Subcortical Projection Neurons Isolated from Murine Embryonic Cortex using Neuropilin-1. Front Cell Neurosci. 2017;11:123 pubmed publisher
Sánchez Mendoza E, Bellver Landete V, Arce C, Doeppner T, Hermann D, Oset Gasque M. Vesicular glutamate transporters play a role in neuronal differentiation of cultured SVZ-derived neural precursor cells. PLoS ONE. 2017;12:e0177069 pubmed publisher
Sando R, Bushong E, Zhu Y, Huang M, Considine C, Phan S, et al. Assembly of Excitatory Synapses in the Absence of Glutamatergic Neurotransmission. Neuron. 2017;94:312-321.e3 pubmed publisher
Altmüller F, Pothula S, Annamneedi A, Nakhaei Rad S, Montenegro Venegas C, Pina Fernández E, et al. Aberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy. PLoS Genet. 2017;13:e1006684 pubmed publisher
Espuny Camacho I, Arranz A, Fiers M, Snellinx A, Ando K, Munck S, et al. Hallmarks of Alzheimer's Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain. Neuron. 2017;93:1066-1081.e8 pubmed publisher
Ripamonti S, Ambrozkiewicz M, Guzzi F, Gravati M, Biella G, Bormuth I, et al. Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons. elife. 2017;6: pubmed publisher
Flynn J, Conn V, Boyle K, Hughes D, Watanabe M, Velasquez T, et al. Anatomical and Molecular Properties of Long Descending Propriospinal Neurons in Mice. Front Neuroanat. 2017;11:5 pubmed publisher
Riessland M, Kaczmarek A, Schneider S, Swoboda K, Löhr H, Bradler C, et al. Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis. Am J Hum Genet. 2017;100:297-315 pubmed publisher
Chen C, Arai I, Satterfield R, Young S, Jonas P. Synaptotagmin 2 Is the Fast Ca2+ Sensor at a Central Inhibitory Synapse. Cell Rep. 2017;18:723-736 pubmed publisher
Kitanishi T, Matsuo N. Organization of the Claustrum-to-Entorhinal Cortical Connection in Mice. J Neurosci. 2017;37:269-280 pubmed publisher
Abraira V, Kuehn E, Chirila A, Springel M, Toliver A, Zimmerman A, et al. The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn. Cell. 2017;168:295-310.e19 pubmed publisher
Bergström P, Agholme L, Nazir F, Satir T, Toombs J, Wellington H, et al. Amyloid precursor protein expression and processing are differentially regulated during cortical neuron differentiation. Sci Rep. 2016;6:29200 pubmed publisher
Imai F, Ladle D, Leslie J, Duan X, Rizvi T, Ciraolo G, et al. Synapse Formation in Monosynaptic Sensory-Motor Connections Is Regulated by Presynaptic Rho GTPase Cdc42. J Neurosci. 2016;36:5724-35 pubmed publisher
You S, Hellström M, Pollett M, LeVaillant C, Moses C, Rigby P, et al. Large-scale reconstitution of a retina-to-brain pathway in adult rats using gene therapy and bridging grafts: An anatomical and behavioral analysis. Exp Neurol. 2016;279:197-211 pubmed publisher
Glebov O, Cox S, Humphreys L, Burrone J. Neuronal activity controls transsynaptic geometry. Sci Rep. 2016;6:22703 pubmed publisher
Sawyer E, Turner E, Kaas J. Somatosensory brainstem, thalamus, and cortex of the California sea lion (Zalophus californianus). J Comp Neurol. 2016;524:1957-75 pubmed publisher
Blosa M, Bursch C, Weigel S, Holzer M, Jäger C, Janke C, et al. Reorganization of Synaptic Connections and Perineuronal Nets in the Deep Cerebellar Nuclei of Purkinje Cell Degeneration Mutant Mice. Neural Plast. 2016;2016:2828536 pubmed publisher
Gessele N, Garcia Pino E, Omerbasic D, Park T, Koch U. Structural Changes and Lack of HCN1 Channels in the Binaural Auditory Brainstem of the Naked Mole-Rat (Heterocephalus glaber). PLoS ONE. 2016;11:e0146428 pubmed publisher
Katsurabayashi S, Kawano H, Ii M, Nakano S, Tatsumi C, Kubota K, et al. Overexpression of Swedish mutant APP in aged astrocytes attenuates excitatory synaptic transmission. Physiol Rep. 2016;4: pubmed publisher
Faralli A, Dagna F, Albera A, Bekku Y, Oohashi T, Albera R, et al. Modifications of perineuronal nets and remodelling of excitatory and inhibitory afferents during vestibular compensation in the adult mouse. Brain Struct Funct. 2016;221:3193-209 pubmed publisher
Vannini E, Restani L, Pietrasanta M, Panarese A, Mazzoni A, Rossetto O, et al. Altered sensory processing and dendritic remodeling in hyperexcitable visual cortical networks. Brain Struct Funct. 2016;221:2919-36 pubmed publisher
Lutz D, Kataria H, Kleene R, Loers G, Chaudhary H, Guseva D, et al. Myelin Basic Protein Cleaves Cell Adhesion Molecule L1 and Improves Regeneration After Injury. Mol Neurobiol. 2016;53:3360-3376 pubmed publisher
Di Prisco G, Huang W, Buffington S, Hsu C, Bonnen P, Placzek A, et al. Translational control of mGluR-dependent long-term depression and object-place learning by eIF2?. Nat Neurosci. 2014;17:1073-82 pubmed publisher
Zeng C, Yang Z, Shreve L, BLEDSOE S, Shore S. Somatosensory projections to cochlear nucleus are upregulated after unilateral deafness. J Neurosci. 2012;32:15791-801 pubmed publisher
Zeng C, Nannapaneni N, Zhou J, Hughes L, Shore S. Cochlear damage changes the distribution of vesicular glutamate transporters associated with auditory and nonauditory inputs to the cochlear nucleus. J Neurosci. 2009;29:4210-7 pubmed publisher
product information
Cat. Nr. :
135 303
Antigen :
VGLUT1
Synonyms :
BNPI, SLC17A7, VGLUT 1
Host Species :
rabbit
Tpye :
polyclonal
Form :
affinity purified
Immunogen :
Recombinant protein corresponding to AA 456 to 560 from rat VGLUT1 (UniProt Id: Q62634)
Reactivity :
human, rat, mouse, cow, goat, sheep, dog
WB :
WB
IP :
IP
ICC :
ICC
IHC :
IHC
IHC P :
IHC-P
EM :
EM
ELISA :
ELISA
KO :
yes
KD :
yes
Quantity :
50 µg
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany