product summary
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company name :
Synaptic Systems
product type :
antibody
product name :
Neuroligin 2
catalog :
129 511
quantity :
100 µg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5,00E+06
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
citations: 12
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:1000; loading ...; fig 3d
Duan J, Pandey S, Li T, Castellano D, Gu X, Li J, et al. Genetic Deletion of GABAA Receptors Reveals Distinct Requirements of Neurotransmitter Receptors for GABAergic and Glutamatergic Synapse Development. Front Cell Neurosci. 2019;13:217 pubmed publisher
  • western blot; mouse; 1:1000; fig 2c
Chmielewska J, Kuzniewska B, Milek J, Urbanska K, Dziembowska M. Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage. Mol Neurobiol. 2019;56:2741-2759 pubmed publisher
  • western blot; mouse; 1:3000; loading ...; fig 4c
Tanabe Y, Naito Y, Vasuta C, Lee A, Soumounou Y, Linhoff M, et al. IgSF21 promotes differentiation of inhibitory synapses via binding to neurexin2?. Nat Commun. 2017;8:408 pubmed publisher
  • western blot; rat; 1 ug/ml; loading ...; tbl 1
Burch A, Tao Cheng J, Dosemeci A. A novel synaptic junction preparation for the identification and characterization of cleft proteins. PLoS ONE. 2017;12:e0174895 pubmed publisher
Garcia J, Gookin S, Crosby K, Schwartz S, Tiemeier E, Kennedy M, et al. Stepwise disassembly of GABAergic synapses during pathogenic excitotoxicity. Cell Rep. 2021;37:110142 pubmed publisher
Paskus J, Tian C, Fingleton E, Shen C, Chen X, Li Y, et al. Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action. Cell Rep. 2019;29:2944-2952.e5 pubmed publisher
Binda C, Nakamura Y, Henley J, Wilkinson K. Sorting nexin 27 rescues neuroligin 2 from lysosomal degradation to control inhibitory synapse number. Biochem J. 2019;: pubmed publisher
Babaev O, Cruces Solis H, Piletti Chatain C, Hammer M, Wenger S, Ali H, et al. IgSF9b regulates anxiety behaviors through effects on centromedial amygdala inhibitory synapses. Nat Commun. 2018;9:5400 pubmed publisher
Li J, Han W, Pelkey K, Duan J, Mao X, Wang Y, et al. Molecular Dissection of Neuroligin 2 and Slitrk3 Reveals an Essential Framework for GABAergic Synapse Development. Neuron. 2017;96:808-826.e8 pubmed publisher
Chanda S, Hale W, Zhang B, Wernig M, Sudhof T. Unique versus Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties. J Neurosci. 2017;37:6816-6836 pubmed publisher
Han K, Woo D, Kim S, Choii G, Jeon S, Won S, et al. Neurotrophin-3 Regulates Synapse Development by Modulating TrkC-PTP? Synaptic Adhesion and Intracellular Signaling Pathways. J Neurosci. 2016;36:4816-31 pubmed publisher
Rathgeber L, Gromova K, Schaefer I, Breiden P, Lohr C, Kneussel M. GSK3 and KIF5 regulate activity-dependent sorting of gephyrin between axons and dendrites. Eur J Cell Biol. 2015;94:173-8 pubmed publisher
product information
Cat. Nr. :
129 511
Antigen :
Neuroligin 2
Synonyms :
Neuroligin2, Nlgn2
Host Species :
mouse
Tpye :
monoclonal
Form :
purified IgG
Cell Line :
5,00E+06
Subtype :
IgG1
Immunogen :
Synthetic peptide corresponding to AA 750 to 767 from rat Neuroligin2 (UniProt Id: Q62888)
Reactivity :
human, rat, mouse
WB :
WB
IP :
IP
ICC :
ICC
IHC :
IHC
KO :
yes
Quantity :
100 µg
more info or order :
company information
Synaptic Systems
Rudolf-Wissell-Str. 28
37079 Goettingen
lab@sysy.com
http://www.sysy.com
49-551-50556-0
headquarters: germany